Biochemical Phenomena - Signal Transduction
PubMed MeSh Term
Overview
subject area of
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(+)-Naloxone, an Opioid-Inactive Toll-Like Receptor 4 Signaling Inhibitor, Reverses Multiple Models of Chronic Neuropathic Pain in Rats Journal Article
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(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes Journal Article
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25 years after age-1: Genes, interventions and the revolution in aging research Journal Article
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ALC ((a)under-bardjacent to (L)under-barMX1 in (c)under-barhick) is a novel dorsal limb mesenchyme marker Journal Article
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Dlx genes integrate positive and negative signals during feather bud development Journal Article
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Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster Journal Article
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A G-protein signaling network mediated by an RGS protein Journal Article
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A Genetic Screen Identifies TCF3/E2A and TRIAP1 as Pathway-Specific Regulators of the Cellular Response to p53 Activation Journal Article
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A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response Journal Article
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A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme Journal Article
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A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages Journal Article
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A POSITIVE FEEDBACK LOOP COORDINATES GROWTH AND PATTERNING IN THE VERTEBRATE LIMB Journal Article
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A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction Journal Article
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A REQUIREMENT FOR FIBROBLAST GROWTH-FACTOR IN REGULATION OF SKELETAL-MUSCLE GROWTH AND DIFFERENTIATION CANNOT BE REPLACED BY ACTIVATION OF PLATELET-DERIVED GROWTH-FACTOR SIGNALING PATHWAYS Journal Article
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A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans Journal Article
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A comparative evaluation of β-catenin and plakoglobin signaling activity Journal Article
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A cuticle collagen encoded by the lon-3 gene may be a target of TGF-β signaling in determining Caenorhabditis elegans body shape Journal Article
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A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation Journal Article
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A hypomorphic allele reveals an important role of inturned in mouse skeletal development Journal Article
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A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4 Journal Article
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A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling Journal Article
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A new role for Notch and Delta in cell fate decisions: patterning the feather array Journal Article
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A novel mechanism for regulating transforming growth factor β (TGF-β) signaling -: Functional modulation of type III TGF-β receptor expression through interaction with the PDZ domain protein, GIPC Journal Article
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A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans Journal Article
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A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint Journal Article
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A role for calreticulin in the adult heart? Journal Article
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A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165 Journal Article
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A vitamin-B2-sensing mechanism that regulates gut protease activity to impact animal's food behavior and growth Journal Article
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A β1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction Journal Article
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ACTIVATING AND INHIBITORY HEPARIN SEQUENCES FOR FGF-2 (BASIC FGF) - DISTINCT REQUIREMENTS FOR FGF-1, FGF-2, AND FGF-4 Journal Article
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AMPK-FOXO-IP3R signaling pathway mediates neurological and developmental defects caused by mitochondrial DNA mutations. Journal Article
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AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila. Journal Article
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Abnormal hypothalamic oxytocin system in fibroblast growth factor 8-deficient mice Journal Article
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Activating and inhibiting connections in biological network dynamics Journal Article
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Activation of Akt as a potential mediator of adaptations that reduce muscle injury Journal Article
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Activation of DNA damage repair pathways by murine polyomavirus Journal Article
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Activation of FAK and Src are receptor-proximal events required for netrin signaling Journal Article
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Activation of Mps1 promotes transforming growth factor-β-independent Smad signaling Journal Article
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Activation of Notch Signaling During Ex Vivo Expansion Maintains Donor Muscle Cell Engraftment Journal Article
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Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy Journal Article
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Activation of the Unfolded Protein Response in Vascular Endothelial Cells of Nondiabetic Obese Adults Journal Article
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Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain Journal Article
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Acute induction of conserved synaptic signaling pathways in Drosophila melanogaster. Journal Article
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Adrenergic receptors mediate stress-induced elevations in extracellular Hsp72 Journal Article
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Aging Is Associated with a Proapoptotic Endothelial Progenitor Cell Phenotype Journal Article
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Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: Pharmacological and signal transduction mechanisms Journal Article
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Alcohol-induced sedation and synergistic interactions between alcohol and morphine: A key mechanistic role for Toll-like receptors and MyD88-dependent signaling Journal Article
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Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models Journal Article
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Alterations in myocardial signal transduction due to aging and chronic dynamic exercise Journal Article
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Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome. Journal Article
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Analysis of Ligand-Dependent Nuclear Accumulation of Smads in TGF-beta Signaling Journal Article
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Analysis of human cGAS activity and structure Chapter
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Anatomic demarcation by positional variation in fibroblast gene expression programs Journal Article
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Ancient and Recent Adaptive Evolution of Primate Non-Homologous End Joining Genes Journal Article
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Ancient evolutionary origin of the neural crest gene regulatory network Journal Article
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Antioxidants in photosynthesis and human nutrition Journal Article
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Antipsychotics activate mTORC1-dependent translation to enhance neuronal morphological complexity. Journal Article
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Apical and basolateral endosomes of MDCK cells are interconnected and contain a polarized sorting mechanism Journal Article
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Applications of mass spectrometry to signal transduction Journal Article
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Applying proteomics to signaling networks Journal Article
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Architecture and signal transduction mechanism of the bacterial chemosensory array: Progress, controversies, and challenges Journal Article
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Association between the oral microbiome and brain resting state connectivity in smokers Journal Article
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Association of v-ErbA with Smad4 Disrupts TGF-beta Signaling Journal Article
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Attenuation of age-related declines in glucagon-mediated signal transduction in rat liver by exercise training Journal Article
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Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment Journal Article
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Attractant regulation of the aspartate receptor-kinase complex: Limited cooperative interactions between receptors and effects of the receptor modification state Journal Article
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Automated discovery of functional generality of human gene expression programs. Journal Article
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Axin and GSK3-β control Smad3 protein stability and modulate TGF-β signaling Journal Article
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BLAST-1995 - INTERNATIONAL-CONFERENCE ON BACTERIAL LOCOMOTION AND SIGNAL-TRANSDUCTION Journal Article
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BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb Journal Article
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BMP signaling and vertebrate limb development Conference Proceeding
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BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors Journal Article
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BMPs negatively regulate structure and function of the limb apical ectodermal ridge Journal Article
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Bacterial chemoreceptors: high-performance signaling in networked arrays Journal Article
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Bone morphogenetic protein signalling and vertebrate nervous system development Journal Article
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Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons Journal Article
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C2cd3 is required for cilia formation and Hedgehog signaling in mouse Journal Article
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CBASS Immunity Uses CARF-Related Effectors to Sense 3′-5′- and 2′-5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection Journal Article
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CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response Journal Article
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CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans Journal Article
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CREB binds to multiple loci on human chromosome 22 Journal Article
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CYTOKINE-TO-BRAIN COMMUNICATION - A REVIEW AND ANALYSIS OF ALTERNATIVE MECHANISMS Journal Article
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Ca2+-signaling cycle of a membrane-docking C2 domain Journal Article
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Cadherins and catenins, Wnts and SOXs: Embryonic patterning in Xenopus Journal Article
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Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction Journal Article
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Calcineurin activates interleukin-6 transcription in mouse skeletal muscle in vivo and in C2C12 myotubes in vitro Journal Article
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Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland Journal Article
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Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension Journal Article
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Cardiac valve cells and their microenvironment-insights from in vitro studies Journal Article
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Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway Journal Article
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Cell corpse engulfment mediated by C-elegans phosphatidylserine receptor through CED-5 and CED-12 Journal Article
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Cell polarity pathways converge and extend to regulate neural tube closure Journal Article
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Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes Journal Article
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Cellular delivery of TGF beta(1) promotes osteoinductive signalling for bone regeneration Journal Article
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Cellular mechanisms of cardiomyopathy Journal Article
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Cellular responses to DNA damage: One signal, multiple choices Journal Article
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Changes in Mouse Thymus and Spleen after Return from the STS-135 Mission in Space Journal Article
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Characterization of the DNA-binding property of Smad5 Journal Article
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CheA kinase of bacterial chemotaxis: Chemical mapping of four essential docking sites Journal Article
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Chemokine Signaling and the Regulation of Bidirectional Leukocyte Migration in Interstitial Tissues Journal Article
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Chemotaxis receptor complexes: From signaling to assembly Journal Article
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Chemotaxis receptors and signaling Journal Article
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Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs Journal Article
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Clinical Neuroscience of Addiction: Similarities and Differences Between Alcohol and Other Drugs Journal Article
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Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Journal Article
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Commensal Bacteria and MAMPs Are Necessary for Stress-Induced Increases in IL-1β and IL-18 but Not IL-6, IL-10 or MCP-1 Journal Article
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Compound Deficiencies in Multiple Fibroblast Growth Factor Signalling Components Differentially Impact the Murine Gonadotrophin-Releasing Hormone System Journal Article
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Concise Review: Mechanisms of Quiescent Hair Follicle Stem Cell Regulation Journal Article
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Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice Journal Article
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Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching Journal Article
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Constitutive activation of extracellular signal-regulated kinase 2 by synergistic point mutations Journal Article
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Control and integration of cell signaling pathways during C-elegans vulval development Journal Article
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Control of cell cycle-dependent degradation of c-Ski proto-oncoprotein by Cdc34 Journal Article
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Coordinate regulation of neural tube patterning and proliferation by TGFβ and WNT activity Journal Article
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Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development Journal Article
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Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins Journal Article
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Crosstalk between nuclear and mitochondrial genomes Journal Article
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Cryoprotectant toxicity in Caenorhabditis elegans Journal Article
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Cycling through development in Drosophila and other metazoa Journal Article
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Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor Journal Article
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Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans Journal Article
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Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus Journal Article
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DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling Journal Article
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DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans Journal Article
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DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats. Journal Article
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Danger Signals and Inflammasomes: Stress-Evoked Sterile Inflammation in Mood Disorders Journal Article
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Decoding the quantitative nature of TGF-β/Smad signaling Journal Article
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Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics Journal Article
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Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice Journal Article
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Decreased insulin-receptor signaling promotes the autophagic degradation of β-amyloid peptide in C-elegans Journal Article
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Decrements in nuclear glucocorticoid receptor (GR) protein levels and DNA binding in aged rat hippocampus Journal Article
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Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation Journal Article
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Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling Journal Article
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Defining a Key Receptor-CheA Kinase Contact and Elucidating Its Function in the Membrane-Bound Bacterial Chemosensory Array: A Disulfide Mapping and TAM-IDS Study Journal Article
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Defining the Cardiac Fibroblast Secretome in a Fibrotic Microenvironment Journal Article
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Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin Journal Article
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Dengue virus non-structural protein 1 activates the p38 MAPK pathway to decrease barrier integrity in primary human endothelial cells Journal Article
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Detection of a conserved alpha-helix in the kinase-docking region of the aspartate receptor by cysteine and disulfide scanning Journal Article
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Development of bat flight: Morphologic and molecular evolution of bat wing digits Journal Article
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Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes Journal Article
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Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice Journal Article
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Developmental regulation of gonadotropin-releasing hormone neurons by fibroblast growth factor signaling Journal Article
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Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling Journal Article
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Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms Journal Article
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Dimensionality and spreading influence MSC YAP/TAZ signaling in hydrogel environments Journal Article
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Discovery of a Novel Site of Opioid Action at the Innate Immune Pattern-Recognition Receptor TLR4 and its Role in Addiction Journal Article
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Discovery of a ZIP7 inhibitor from a Notch pathway screen Journal Article
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Dissociated Hippocampal Neurons Exhibit Distinct Zn2+ Dynamics in a Stimulation-Method-Dependent Manner Journal Article
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Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior Journal Article
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Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis Journal Article
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Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage Journal Article
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Diurnal variation in nicotine sensitivity in mice: Role of genetic background and melatonin Journal Article
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Downregulation of MicroRNA miR-526a by Enterovirus Inhibits RIG-I-Dependent Innate Immune Response Journal Article
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Drosophila Polypyrimidine Tract-Binding Protein (DmPTB) Regulates Dorso-Ventral Patterning Genes in Embryos Journal Article
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Dynamic loading stimulates chondrocyte biosynthesis when encapsulated in charged hydrogels prepared from poly(ethylene glycol) and chondroitin sulfate Journal Article
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Dynamic mechanical loading and growth factors influence chondrogenesis of induced pluripotent mesenchymal progenitor cells in a cartilage-mimetic hydrogel Journal Article
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Dynamic regulation of the proinflammatory cytokine, interleukin-1 beta: Molecular biology for non-molecular biologists Journal Article
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Dynamics of TGF-β/Smad signaling Journal Article
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Dysregulation of mTOR signaling in fragile X syndrome. Journal Article
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Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease. Journal Article
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EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway Journal Article
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EGF signaling patterns the feather array by promoting the interbud fate Journal Article
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EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism Journal Article
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EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF Journal Article
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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals Journal Article
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ER stress signaling by regulated proteolysis of ATF6 Journal Article
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ERK1/2 activation is a therapeutic target in age-related macular degeneration Journal Article
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EVIDENCE FOR A ROLE OF HEAT SHOCK PROTEIN-90 IN TOLL LIKE RECEPTOR 4 MEDIATED PAIN ENHANCEMENT IN RATS Journal Article
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EVIDENCE THAT TRICYCLIC SMALL MOLECULES MAY POSSESS TOLL-LIKE RECEPTOR AND MYELOID DIFFERENTIATION PROTEIN 2 ACTIVITY Journal Article
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Effects of adenosine A2A receptor stimulation on cocaine-seeking behavior in rats Journal Article
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Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast - Evidence for a signaling pathway from the mitochondrial genome to the nucleus Journal Article
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Effects of transmembrane and juxtamembrane domains on proliferative ability of TSLP receptor Journal Article
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Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer. Journal Article
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Endoplasmic reticulum-mitochondria contacts: function of the junction Journal Article
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Endothelial SUR-8 Acts in an ERK-Independent Pathway During Atrioventricular Cushion Development Journal Article
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Engineered Culture Models for Studies of Tumor-Microenvironment Interactions Journal Article
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Engineered Socket Study of Signaling through a Four-Helix Bundle: Evidence for a Yin-Yang Mechanism in the Kinase Control Module of the Aspartate Receptor Journal Article
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Engineering synthetic hydrogel microenvironments to instruct stem cells Journal Article
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Enhancement of beta-globin locus control region-mediated transactivation by mitogen-activated protein kinases through stochastic and graded mechanisms Journal Article
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Ephrin signalling controls brain size by regulating apoptosis of neural progenitors Journal Article
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Epithelial-mesenchymal crosstalk influences cellular behavior in a 3D alveolus-fibroblast model system Journal Article
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Estrogen receptor profiling and activity in cardiac myocytes Journal Article
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Evidence that both ligand binding and covalent adaptation drive a two-state equilibrium in the aspartate receptor signaling complex Journal Article
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Evidence that opioids may have toll-like receptor 4 and MD-2 effects Journal Article
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Evolution of the endothelin pathway drove neural crest cell diversification Journal Article
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Evolution of the new vertebrate head by co-option of an ancient chordate skeletal tissue Journal Article
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Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy Journal Article
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Exosomes: An emerging factor in stress-induced immunomodulation Journal Article
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Exploring the Neuroimmunopharmacology of Opioids: An Integrative Review of Mechanisms of Central Immune Signaling and Their Implications for Opioid Analgesia Journal Article
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Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP:TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of COVID-19 Journal Article
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Expression of a dominant negative FGF receptor in developing GNRH1 neurons disrupts axon outgrowth and targeting to the median eminence Journal Article
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Extracellular Metabolism Sets the Table for Microbial Cross-Feeding Journal Article
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Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling Journal Article
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FGF-4 AND BMP-2 HAVE OPPOSITE EFFECTS ON LIMB GROWTH Journal Article
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Fgf signaling is required for zebrafish tooth development Journal Article
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Fibroblast Growth Factor Signaling Deficiencies Impact Female Reproduction and Kisspeptin Neurons in Mice Journal Article
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Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons Journal Article
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Fibroblast growth factor represses Smad-mediated myofibroblast activation in aortic valvular interstitial cells Journal Article
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Fibroblast growth factor signaling in the developing neuroendocrine hypothalamus Journal Article
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Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles Journal Article
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Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling Journal Article
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Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Journal Article
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Functional Analysis of Neuronal MicroRNAs in Caenorhabditis elegans Dauer Formation by Combinational Genetics and Neuronal miRISC Immunoprecipitation Journal Article
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Functional genomic analysis of apoptotic DNA degradation in C-elegans Journal Article
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Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling Journal Article
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G alpha 12 and G alpha 13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells Journal Article
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GCN5 acetylation is required for craniofacial chondrocyte maturation Journal Article
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Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons Journal Article
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Gene-regulatory interactions in neural crest evolution and development Journal Article
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Genes That Escape X Chromosome Inactivation Modulate Sex Differences in Valve Myofibroblasts Journal Article
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Genetic and Apoptotic Changes in Lungs of Mice Flown on the STS-135 Mission in Space Journal Article
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Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C-elegans development Journal Article
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Genetics of RAS signaling in C-elegans Journal Article
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Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus Journal Article
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Get off my back! Rapid receptor internalization through circular dorsal ruffles Journal Article
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Get on the exosome bus with ALIX Journal Article
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Getting signals crossed in C-elegans Journal Article
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Glia as the "bad guys": Implications for improving clinical pain control and the clinical utility of opioids Journal Article
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Glial TLR4 signaling does not contribute to opioid-induced depression of respiration Journal Article
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Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses Journal Article
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Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain Journal Article
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Growth of limb muscle is dependent on skeletal-derived Indian hedgehog Journal Article
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Gut reaction to Wnt signaling in worms Journal Article
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HEB and E2A function as SMAD/FOXH1 cofactors Journal Article
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HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia Journal Article
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Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model Journal Article
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Hedgehog signaling is required at multiple stages of zebrafish tooth development Journal Article
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Hedgehog signalling controls eye degeneration in blind cavefish Journal Article
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Hedgehog signalling in the mouse requires intraflagellar transport proteins Journal Article
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Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans Journal Article
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Heterogeneous dopamine signals support distinct features of motivated actions: implications for learning and addiction Journal Article
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Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization Journal Article
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High-fat diet, microbiome-gut-brain axis signaling, and anxiety-like behavior in male rats Journal Article
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Hopeful monsters and morphogens at the beach Journal Article
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Hormesis and aging in Caenorhabditis elegans Journal Article
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How to initiate tissue regeneration by generating mutually exclusive cell states Journal Article
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Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells Journal Article
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Human Papillomavirus 16 oncoprotein E7 retards mitotic progression by blocking Mps1-MAP4 signaling cascade Journal Article
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Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway Journal Article
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INHIBITION OF A SIGNALING PATHWAY IN CARDIAC-MUSCLE-CELLS BY ACTIVE MITOGEN-ACTIVATED PROTEIN-KINASE KINASE Journal Article
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INTERACTION BETWEEN THE SIGNALING MOLECULES WNT7A AND SHH DURING VERTEBRATE LIMB DEVELOPMENT - DORSAL SIGNALS REGULATE ANTEROPOSTERIOR PATTERNING Journal Article
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Identification of G2/M targets for the MAP kinase pathway by functional proteomics Journal Article
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Identification of Tyrosine-9 of MAVS as Critical Target for Inducible Phosphorylation That Determines Activation Journal Article
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Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry Journal Article
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Identifying Recent Adaptations in Large-Scale Genomic Data Journal Article
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Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling Journal Article
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Immune-to-central nervous system communication and its role in modulating pain and cognition: Implications for cancer and cancer treatment Journal Article
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Impaired endothelium-dependent vasodilation in overweight and obese adult humans is not limited to muscarinic receptor agonists Journal Article
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In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements Journal Article
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Increasing and Decreasing the Ultrastability of Bacterial Chemotaxis Core Signaling Complexes by Modifying Protein-Protein Contacts Journal Article
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Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis Journal Article
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Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo Journal Article
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Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts Journal Article
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Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly(ethylene glycol) hydrogels Journal Article
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Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice Journal Article
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Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis Journal Article
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Inhibition of c-Kit signaling is associated with reduced heat and cold pain sensitivity in humans Journal Article
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Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis Journal Article
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Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking Journal Article
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Insulin Signaling and Heart Failure Journal Article
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Insulin-like Signaling Determines Survival during Stress via Posttranscriptional Mechanisms in C. elegans Journal Article
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Integrated analysis of directly captured microRNA targets reveals the impact of microRNAs on mammalian transcriptome Journal Article
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Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling Journal Article
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Interleukin-1 beta: a potential link between stress and the development of visceral obesity. Journal Article
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Interleukin-1 induces c-Fos immunoreactivity in primary afferent neurons of the vagus nerve Journal Article
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Interplay between the molecular signals that control vertebrate limb development Journal Article
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Interventions to Slow Aging in Humans: Are We Ready? Journal Article
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Intracellular Zn2+ transients modulate global gene expression in dissociated rat hippocampal neurons Journal Article
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Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling Journal Article
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Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development Journal Article
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Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects? Journal Article
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Isolated Bacterial Chemosensory Array Possesses Quasi- and Ultrastable Components: Functional Links between Array Stability, Cooperativity, and Order Journal Article
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Jagged1 immobilization to an osteoconductive polymer activates the Notch signaling pathway and induces osteogenesis Journal Article
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KINETIC CONTROL OF CA(II) SIGNALING - TUNING THE ION DISSOCIATION RATES OF EF-HAND CA(II) BINDING-SITES Journal Article
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Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization Journal Article
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LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer Journal Article
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LOCK ON OFF DISULFIDES IDENTIFY THE TRANSMEMBRANE SIGNALING HELIX OF THE ASPARTATE RECEPTOR Journal Article
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Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk Journal Article
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Lessons on transcriptional control from the serum response network Journal Article
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Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans Journal Article
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Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans Journal Article
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Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-β signaling Journal Article
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Loaded wheel running and muscle adaptation in the mouse Journal Article
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Local nascent protein deposition and remodelling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels Journal Article
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Localizing the adhesive and signaling functions of plakoglobin Journal Article
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Loss of FGF receptor 1 signaling reduces skeletal muscle mass and disrupts myofiber organization in the developing limb Journal Article
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Loss of neurotrophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation Journal Article
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Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain Journal Article
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Lung epithelial cells release ATP during ozone exposure: Signaling for cell survival Journal Article
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MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3 Journal Article
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MEK-2, A CAENORHABDITIS-ELEGANS MAP KINASE KINASE, FUNCTIONS IN RAS-MEDIATED VULVAR INDUCTION AND OTHER DEVELOPMENTAL EVENTS Journal Article
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MITOGEN-ACTIVATED PROTEIN (MAP) KINASE PHOSPHORYLATION OF MAP KINASE KINASE - DETERMINATION OF PHOSPHORYLATION SITES BY MASS-SPECTROMETRY AND SITE-DIRECTED MUTAGENESIS Journal Article
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Mitochondrial Cell Death Pathways in Caenorhabiditis elegans Journal Article
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Molecular functions of the TLE tetramerization domain in Wnt target gene repression Journal Article
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Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors Journal Article
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Mps1 kinase regulates tumor cell viability via its novel role in mitochondria Journal Article
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Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation Journal Article
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Multiple pathways of mitochondrial-nuclear communication in yeast: Intergenomic signaling involves ABF1 and affects a different set of genes than retrograde regulation Journal Article
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Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection Journal Article
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Muscle atrophy in transgenic mice expressing a human TSC1 transgene Journal Article
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Muscle stem cells on the edge Journal Article
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Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice Journal Article
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Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression Journal Article
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Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling Journal Article
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Nitroxidative Signaling Mechanisms in Pathological Pain Journal Article
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Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis Journal Article
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Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4) Journal Article
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Noncoding RNAs: biology and applications-a Keystone Symposia report Journal Article
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Nongenetic Bioconjugation Strategies for Modifying Cell Membranes and Membrane Proteins: A Review Journal Article
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Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation Journal Article
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Notch mRNA Expression in Drosophila Embryos Is Negatively Regulated at the Level of mRNA 3 ' Processing Journal Article
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Notch signaling protects animals from nucleotide deficiency Journal Article
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Nuclear envelope wrinkling predicts mesenchymal progenitor cell mechano-response in 2D and 3D microenvironments Journal Article
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Nuclear localization of mitogen-activated protein kinase kinase 1 (MKK1) is promoted by serum stimulation and G2-M progression - Requirement for phosphorylation at the activation lip and signaling downstream of MKK Journal Article
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Nucleic acid-protein condensates in innate immune signaling Journal Article
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Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans Journal Article
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Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling Journal Article
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Oncogenes and tumor angiogenesis:: Differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts Journal Article
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Oncogenic Ras-induced proliferation requires autocrine fibroblast growth factor 2 signaling in skeletal muscle cells Journal Article
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Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy Journal Article
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Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement Journal Article
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Opioid Self-Administration is Attenuated by Early-Life Experience and Gene Therapy for Anti-Inflammatory IL-10 in the Nucleus Accumbens of Male Rats Journal Article
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Opioid-Induced Central Immune Signaling: Implications for Opioid Analgesia Journal Article
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Opposite-sex housing reactivates the declining GnRH system in aged transgenic male mice with FGF signaling deficiency Journal Article
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Optogenetic interrogation and control of cell signaling Journal Article
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Oxygen sensing and molecular adaptation to hypoxia Journal Article
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Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling Journal Article
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PDK1:PKCa heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane Journal Article
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PHOSPHORYLATION OF THE C-TERMINAL DOMAIN OF RNA-POLYMERASE-II BY THE EXTRACELLULAR-SIGNAL-REGULATED PROTEIN-KINASE ERK2 Journal Article
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PORE-ing over ERK substrates Journal Article
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Pathological and protective roles of glia in chronic pain Journal Article
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Pathological pain and the neuroimmune interface Journal Article
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Pathway- and expression level-dependent effects of oncogenic N-Ras:: p27Kip1 mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling Journal Article
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Pathways Underlying Afferent Signaling of Bronchopulmonary Immune Activation to the Central Nervous System Journal Article
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Pattern Formation in the Longevity-Related Expression of Heat Shock Protein-16.2 in Caenorhabditis elegans Journal Article
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Peroxisome proliferator-activated receptor γ inhibits transforming growth factor β-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3 Journal Article
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Perspectives in innate and acquired cardioprotection: cardioprotection acquired through exercise Journal Article
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Phactr4 A new integrin modulator required for directional migration of enteric neural crest cells Journal Article
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Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity Journal Article
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Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR Journal Article
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Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions Journal Article
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Phosphoinositide signaling and the regulation of membrane trafficking in yeast Journal Article
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Phosphorylation of I kappa B-alpha inhibits its cleavage by caspase CPP32 in vitro Journal Article
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Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells Journal Article
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Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay Journal Article
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Pregnancy as a cardiac stress model Journal Article
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Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB Journal Article
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Programmed Cell Death During Caenorhabditis elegans Development Journal Article
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Programmed cell clearance: From nematodes to humans Journal Article
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Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor Journal Article
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Proteomic Analysis of Mouse Brain Subjected to Spaceflight Journal Article
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways Journal Article
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Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: Development of a heterogeneous two-state model Journal Article
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Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics Journal Article
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Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals Journal Article
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Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice. Journal Article
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RAS FARNESYLTRANSFERASE INHIBITORS SUPPRESS THE PHENOTYPE RESULTING FROM AN ACTIVATED RAS MUTATION IN CAENORHABDITIS-ELEGANS Journal Article
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REGULATION BY HEPARAN-SULFATE IN FIBROBLAST GROWTH-FACTOR SIGNALING Book
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RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling Journal Article
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ROLE OF A RAF PROTOONCOGENE DURING CAENORHABDITIS-ELEGANS VULVAR DEVELOPMENT Journal Article
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ROLE OF FGFS IN SKELETAL-MUSCLE AND LIMB DEVELOPMENT Journal Article
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ROLE OF THE SYK AUTOPHOSPHORYLATION SITE AND SH2 DOMAINS IN B-CELL ANTIGEN RECEPTOR SIGNALING Journal Article
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RSG1 is required for cilia-dependent neural tube closure Journal Article
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Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye Journal Article
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Ras proteins in developmental pattern formation in Caenorhabditis elegans and Drosophila. Journal Article
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Ras signaling mechanisms: New insights from single-molecule biophysics. Journal Article
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Receptor downregulation and multivesicular-body sorting Journal Article
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Reducing Tumour Hypoxia via Oral Administration of Oxygen Nanobubbles Journal Article
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Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus specific Journal Article
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Regression of postprandial cardiac hypertrophy in burmese pythons is mediated by FoxO1. Journal Article
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Regulation of Kinetochore Recruitment of Two Essential Mitotic Spindle Checkpoint Proteins by Mps1 Phosphorylation Journal Article
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Regulation of Nucleotide Metabolism and Germline Proliferation in Response to Nucleotide Imbalance and Genotoxic Stresses by EndoU Nuclease Journal Article
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Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway Journal Article
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Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification Journal Article
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Regulation of Wnt signaling by sox proteins:: XSox17α/β and XSox3 physically interact with β-catenin Journal Article
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Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module Journal Article
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Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis-toxin-sensitive G proteins Journal Article
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Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors Journal Article
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Regulation of skeletal muscle stem cells by fibroblast growth factors Journal Article
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Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb Journal Article
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Releasing signals, secretory pathways, and immune function of endogenous extracellular heat shock protein 72 Journal Article
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Repeated Morphine Prolongs Postoperative Pain in Male Rats Journal Article
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Repositioning Antimicrobial Agent Pentamidine as a Disruptor of the Lateral Interactions of Transmembrane Domain 5 of EBV Latent Membrane Protein 1 Journal Article
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Requirement for BMP signaling in interdigital apoptosis and scale formation Journal Article
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Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain Journal Article
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Role of Fibroblast Growth Factor Signaling in Gonadotropin-Releasing Hormone Neuronal System Development Journal Article
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Role of light and jasmonic acid signaling in regulating foliar phloem cell wall ingrowth development Journal Article
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Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells Journal Article
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Role of the dorsomedial hypothalamus in glucocorticoid-mediated feedback inhibition of the hypothalamic-pituitary-adrenal axis Journal Article
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Roles for FGF in lamprey pharyngeal pouch formation and skeletogenesis highlight ancestral functions in the vertebrate head Journal Article
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SBML Level 3 package: Hierarchical Model Composition, Version 1 Release 3 Journal Article
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SKR-1, a homolog of Skp1 and a member of the SCFSEL-10 complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans Journal Article
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SUPPRESSION OF ACTIVATED LET-60 RAS PROTEIN DEFINES A ROLE OF CAENORHABDITIS-ELEGANS SUR-1 MAP KINASE IN VULVAR DIFFERENTIATION Journal Article
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SUR-2, A NOVEL GENE, FUNCTIONS LATE IN THE LET-60 RAS-MEDIATED SIGNALING PATHWAY DURING CAENORHABDITIS-ELEGANS VULVAR INDUCTION Journal Article
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SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C-elegans Journal Article
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Secreted Factors From Proinflammatory Macrophages Promote an Osteoblast-Like Phenotype in Valvular Interstitial Cells Journal Article
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Sexually Dimorphic BDNF Signaling Directs Sensory Innervation of the Mammary Gland Journal Article
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Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor Journal Article
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Signal transduction through MAP kinase cascades Journal Article
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Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles Journal Article
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Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update Journal Article
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Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: Cysteine and disulfide scanning studies Journal Article
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Single Cell Imaging to Probe Mesenchymal Stem Cell N-Cadherin Mediated Signaling within Hydrogels Journal Article
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Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin Journal Article
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Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling Journal Article
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Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC Journal Article
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Ski/Sno and TGF-β signaling Journal Article
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SnoN and Ski protooncoproteins ave rapidly degraded in response to transforming growth factor β signaling Journal Article
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Spatiotemporal Control of TGF-β Signaling with Light Journal Article
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Spatiotemporal Dynamics of Complement C5a Production within Bacterial Extracellular Polymeric Substance Journal Article
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Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells Journal Article
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Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways Journal Article
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Stability analysis of the GAL regulatory network in Saccharomyces cerevisiae and Kluyveromyces lactis Journal Article
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Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans Journal Article
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Stem cell quiescence acts as a tumour suppressor in squamous tumours Journal Article
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Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling Journal Article
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Strategies to reduce dendritic cell activation through functional biomaterial design Journal Article
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Stress-evoked sterile inflammation, danger associated molecular patterns (DAMPs), microbial associated molecular patterns (MAMPs) and the inflammasome Journal Article
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Stress-induced glucocorticoids as a neuroendocrine alarm signal of danger Journal Article
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Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA Journal Article
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Superoxide signaling in perivascular adipose tissue promotes age-related artery stiffness Journal Article
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Temperature Control of Fimbriation Circuit Switch in Uropathogenic Escherichia coli: Quantitative Analysis via Automated Model Abstraction Journal Article
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Temporal Metabolite, Ion, and Enzyme Activity Profiling Using Fluorescence Microscopy and Genetically Encoded Biosensors Journal Article
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Temporal integration of mitogen history in mother cells controls proliferation of daughter cells Journal Article
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The Ptch1(DL) Mouse: A New Model to Study Lambdoid Craniosynostosis and Basal Cell Nevus Syndrome-Associated Skeletal Defects Journal Article
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The Superfast Human Extraocular Myosin Is Kinetically Distinct from the Fast Skeletal IIa, IIb, and IId Isoforms Journal Article
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The fatty acid synthase fasn-1 acts upstream of WNK and Ste20/GCK-VI kinases to modulate antimicrobial peptide expression in C. elegans epidermis Journal Article
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The impact of acute-stressor exposure on splenic innate immunity: A gene expression analysis Journal Article
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The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf Journal Article
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The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring Journal Article
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The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis Journal Article
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The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis Journal Article
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The two-component signaling pathway of bacterial chemotaxis: A molecular view of signal transduction by receptors, kinases, and adaptation enzymes Journal Article
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Three-Dimensional Mechanical Loading Modulates the Osteogenic Response of Mesenchymal Stem Cells to Tumor-Derived Soluble Signals Journal Article
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Toll-like receptors and their role in persistent pain Journal Article
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Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation Journal Article
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Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions Journal Article
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Transmembrane Peptides Used to Investigate the Homo-Oligomeric Interface and Binding Hotspot of Latent Membrane Protein 1 Journal Article
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p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice Journal Article
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β-Amyloid disruption of LTP/LTD balance is mediated by AKAP150-anchored PKA and Calcineurin regulation of Ca2+-permeable AMPA receptors Journal Article
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