A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint
Journal Article
Overview
publication date
- June 1, 2009
has subject area
- Alkaloids - Caffeine
- Aminoglycosides - Daunorubicin
- Biochemical Phenomena - DNA Replication
- Biochemical Phenomena - Promoter Regions, Genetic
- Biochemical Phenomena - S Phase
- Biochemical Phenomena - Signal Transduction
- Carrier Proteins - Ataxia Telangiectasia Mutated Proteins
- Carrier Proteins - Cyclin-Dependent Kinase Inhibitor p21
- Carrier Proteins - Tumor Suppressor Protein p53
- Cell Cycle Proteins
- Cell Cycle Proteins - Cyclin-Dependent Kinase Inhibitor p21
- Cell Line - HCT116 Cells
- Cell Physiological Phenomena - Signal Transduction
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- DNA-Binding Proteins - Tumor Suppressor Protein p53
- Gene Expression Regulation, Neoplastic
- Genetic Phenomena - DNA Replication
- Genetic Phenomena - S Phase
- Genetic Structures - Promoter Regions, Genetic
- Humans
- Hydrocarbons, Aromatic - Daunorubicin
- Hydroxyurea
- Interphase - S Phase
- Nuclear Proteins - Ataxia Telangiectasia Mutated Proteins
- Nuclear Proteins - Cyclin-Dependent Kinase Inhibitor p21
- Nuclear Proteins - Tumor Suppressor Protein p53
- Nucleic Acid Synthesis Inhibitors
- Peptides - Cyclin-Dependent Kinase Inhibitor p21
- Phosphoproteins - Tumor Suppressor Protein p53
- Polycyclic Compounds - Daunorubicin
- Protein Kinases
- Protein-Serine-Threonine Kinases
- Protein-Serine-Threonine Kinases - Ataxia Telangiectasia Mutated Proteins
- Proteins - Cyclin-Dependent Kinase Inhibitor p21
- Purinones - Caffeine
- RNA, Messenger
- Regulatory Elements, Transcriptional - Promoter Regions, Genetic
- Transcription Factors
- Tumor Cells, Cultured - HCT116 Cells
- Tumor Suppressor Proteins - Cyclin-Dependent Kinase Inhibitor p21
- Tumor Suppressor Proteins - Tumor Suppressor Protein p53
has restriction
- gold
Date in CU Experts
- September 9, 2013 10:33 AM
Full Author List
- Beckerman R; Donner AJ; Mattia M; Peart MJ; Manley JL; Espinosa JM; Prives C
author count
- 7
citation count
- 49
published in
- Genes and Development Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0890-9369
Electronic International Standard Serial Number (EISSN)
- 1549-5477
Digital Object Identifier (DOI)
Additional Document Info
start page
- 1364
end page
- 1377
volume
- 23
issue
- 11