subject area of
- Neat1 is a p53-inducible lincRNA essential for transformation suppression Journal Article
- Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 Journal Article
- A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX Journal Article
- A Genetic Screen Identifies TCF3/E2A and TRIAP1 as Pathway-Specific Regulators of the Cellular Response to p53 Activation Journal Article
- A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response Journal Article
- A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response Journal Article
- A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint Journal Article
- ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels Journal Article
- Allosteric drugs: thinking outside the active-site box. Journal Article
- BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death Journal Article
- Back to Bases: How a Nucleotide Biosynthetic Enzyme Controls p53 Activation Journal Article
- CDK8 is a stimulus-specific positive coregulator of p53 target genes Journal Article
- Cells with loss-of-heterozygosity after exposure to ionizing radiation inDrosophilaare culled by p53-dependent and p53-independent mechanisms Journal Article
- Cellular zinc status alters chromatin accessibility and binding of p53 to DNA. Journal Article
- Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells Journal Article
- Configurational Preferences of Arylamide alpha-Helix Mimetics via Alchemical Free Energy Calculations of Relative Binding Affinities Journal Article
- Delta Np63 alpha represses anti-proliferative genes via H2A.Z deposition Journal Article
- Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes Journal Article
- E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila Journal Article
- Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function Journal Article
- Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding Journal Article
- Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program Journal Article
- Genome-Wide Expression Analysis Identifies a Modulator of Ionizing Radiation-Induced p53-Independent Apoptosis in Drosophila melanogaster Journal Article
- Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms Journal Article
- Hot-spot mutants of p53 core domain evince characteristic local structural changes. Journal Article
- How does Delta Np63 alpha drive cancer? Journal Article
- Identification of PARN nuclease activity inhibitors by computational-based docking and high-throughput screening Journal Article
- Identification of proteins binding coding and non-coding human RNAs using protein microarrays Journal Article
- In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements Journal Article
- Integrated genomics approaches identify transcriptional mediators and epigenetic responses to Afghan desert particulate matter in small airway epithelial cells Journal Article
- Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage Journal Article
- Ionizing radiation induces caspase-dependent but Chk2-and p53-independent cell death in Drosophila melanogaster Journal Article
- Loss of p53 expression in cancer cells alters cell cycle response after inhibition o f exportin-1 but does not prevent cell death Journal Article
- Mechanisms of regulatory diversity within the p53 transcriptional network Journal Article
- Mediator and post-recruitment regulation of RNA polymerase II. Journal Article
- Mitochondrial activity, embryogenesis, and the dialogue between the big and little brains of the cell Journal Article
- Modeling of Arylamide Helix Mimetics in the p53 Peptide Binding Site of hDM2 Suggests Parallel and Anti-Parallel Conformations Are Both Stable Journal Article
- Modulation of ionizing radiation-induced apoptosis by bantam microRNA in Drosophila Journal Article
- Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation Journal Article
- Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction Journal Article
- Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity Journal Article
- Repression of p53-mediated transcription by MDM2: a dual mechanism Journal Article
- Single molecule studies characterize the kinetic mechanism of tetrameric p53 binding to different native response elements Journal Article
- Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites Journal Article
- Stability of p53 Homologs Journal Article
- Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding Journal Article
- Stem cell quiescence acts as a tumour suppressor in squamous tumours Journal Article
- Stimulus-specific transcriptional regulation within the p53 network Journal Article
- Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation". Journal Article
- Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide Journal Article
- TRANSLATIONAL ONCOLOGY A signature for success Journal Article
- Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis Journal Article
- The RNase PARN Controls the Levels of Specific miRNAs that Contribute to p53 Regulation Journal Article
- The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p Journal Article
- The human ΔNp53 isoform triggers metabolic and gene expression changes that activate mTOR and alter mitochondrial function. Journal Article
- The impact of post-transcriptional regulation in the p53 network Journal Article
- The p53 circuit board Journal Article
- The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation Journal Article
- Thermodynamic stability of wild-type and mutant p53 core domain. Journal Article
- To repress or not to repress: This is the guardian's question Journal Article
- Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant Journal Article
- Transcription factor enrichment analysis (TFEA) quantifies the activity of multiple transcription factors from a single experiment Journal Article
- Tumor Suppression by p53: Is Apoptosis Important or Not? Journal Article
- Using electrophoretic mobility shift assays to measure equilibrium dissociation constants: GAL4-p53 binding DNA as a model system Journal Article
- Visual, base-specific detection of nucleic acid hybridization using polymerization-based amplification Journal Article
- Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation Journal Article
- p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer Journal Article
- p53 activates transcription by directing structural shifts in Mediator Journal Article
- p53 regulates enhancer accessibility and activity in response to DNA damage Journal Article
- p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress Journal Article
- p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress Journal Article
- ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells Journal Article