BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death
Journal Article
Overview
publication date
- July 1, 2008
has subject area
- Amides - Sulfonamides
- Apoptosis
- Biochemical Phenomena - Down-Regulation
- Biphenyl Compounds
- Carrier Proteins - Tumor Suppressor Protein p53
- Cell Cycle
- Cell Cycle Proteins
- Cell Line - Cell Line, Tumor
- DNA-Binding Proteins - Tumor Suppressor Protein p53
- Gene Expression Regulation - Down-Regulation
- Humans
- Imidazoles
- Nitro Compounds - Nitrophenols
- Nuclear Proteins
- Nuclear Proteins - Tumor Suppressor Protein p53
- Peptides - Proto-Oncogene Proteins c-bcl-2
- Peptides - bcl-2 Homologous Antagonist-Killer Protein
- Peptides - bcl-2-Associated X Protein
- Pharmacological Phenomena - Down-Regulation
- Phenols - Nitrophenols
- Phosphoproteins - Tumor Suppressor Protein p53
- Piperazines
- Proteins - Proto-Oncogene Proteins c-bcl-2
- Proteins - bcl-2 Homologous Antagonist-Killer Protein
- Proteins - bcl-2-Associated X Protein
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins - Proto-Oncogene Proteins c-bcl-2
- Sulfones - Sulfonamides
- Tumor Cells, Cultured - Cell Line, Tumor
- Tumor Suppressor Proteins - Tumor Suppressor Protein p53
has restriction
- bronze
Date in CU Experts
- September 9, 2013 10:33 AM
Full Author List
- Wade M; Rodewald LW; Espinosa JM; Wahl GM
author count
- 4
citation count
- 43
published in
- Cell Cycle Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1538-4101
Digital Object Identifier (DOI)
Additional Document Info
start page
- 1973
end page
- 1982
volume
- 7
issue
- 13