Cell Line - Cell Line, Tumor
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15-Deoxy-12,14-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2 and activates the integrated stress response Journal Article
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TERT promoter mutations and telomerase reactivation in urothelial cancer Journal Article
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A Cell-Cycle "Safe Space" for Surviving Chemotherapy Journal Article
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A Genetic Screen Identifies TCF3/E2A and TRIAP1 as Pathway-Specific Regulators of the Cellular Response to p53 Activation Journal Article
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A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme Journal Article
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A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells Journal Article
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A Quantitative Comparison of Human HT-1080 Fibrosarcoma Cells and Primary Human Dermal Fibroblasts Identifies a 3D Migration Mechanism with Properties Unique to the Transformed Phenotype Journal Article
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A Selective Inhibitor and Probe of the Cellular Functions of Jumonji C Domain-Containing Histone Demethylases Journal Article
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A Simulated MS/MS Library for Spectrum-to-spectrum Searching in Large Scale Identification of Proteins Journal Article
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A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model Journal Article
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A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics Journal Article
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A concise total synthesis of largazole, solution structure, and some preliminary structure activity relationships Journal Article
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A dual parameter FRET probe for measuring PKC and PKA activity in living cells Journal Article
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A microfluidic system for cell type classification based on cellular size-independent electrical properties Journal Article
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A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells Journal Article
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A photoclickable peptide microarray platform for facile and rapid screening of 3-D tissue microenvironments Journal Article
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A putative N-terminal nuclear export sequence is sufficient for Mps1 nuclear exclusion during interphase Journal Article
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A reconfigurable microscale assay enables insights into cancer-associated fibroblast modulation of immune cell recruitment Journal Article
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A synthetic modular approach for modeling the role of the 3D microenvironment in tumor progression Journal Article
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A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer Journal Article
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ATF6-Mediated Signaling Contributes to PARP Inhibitor Resistance in Ovarian Cancer Journal Article
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ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure Journal Article
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Absence of mutations in DICE1/DDX26 gene in human cancer cell lines with frequent 13q14 deletions Journal Article
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Activation of Mps1 promotes transforming growth factor-β-independent Smad signaling Journal Article
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Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes Journal Article
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Allele-specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates withTERTexpression in multiple cancers Journal Article
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Alternative CHRNB4 3'-UTRs Mediate the Allelic Effects of SNP rs1948 on Gene Expression Journal Article
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An endogenous retrovirus regulates tumor-specific expression of the immune transcriptional regulator SP140 Journal Article
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Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics Journal Article
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Anti-EGFR Affibodies with Site-Specific Photo-Cross-Linker Incorporation Show Both Directed Target-Specific Photoconjugation and Increased Retention in Tumors Journal Article
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Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells. Journal Article
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Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma Journal Article
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Autophagy Controls the Kinetics and Extent of Mitochondrial Apoptosis by Regulating PUMA Levels Journal Article
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BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death Journal Article
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Bouvardin is a Radiation Modulator with a Novel Mechanism of Action Journal Article
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CDK8 is a positive regulator of transcriptional elongation within the serum response network. Journal Article
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CDK8 is a stimulus-specific positive coregulator of p53 target genes Journal Article
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Cancer-linked satellite 2 DNA hypomethylation does not regulate Sat2 non-coding RNA expression and is initiated by heat shock pathway activation Journal Article
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Cationic gold nanoparticles elicit mitochondrial dysfunction: a multi-omics study Journal Article
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Cell death when the SAC is out of commission Journal Article
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Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing β-cell function Journal Article
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Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes Journal Article
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Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules Journal Article
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Chandipura viral glycoprotein (CNV-G) promotes Gectosome generation and enables delivery of intracellular therapeutics. Journal Article
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Characterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATp. Journal Article
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Click Nucleic Acid Mediated Loading of Prodrug Activating Enzymes in PEG-PLGA Nanoparticles for Combination Chemotherapy Journal Article
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Combined EGFR1 and PARP1 Inhibition Enhances the Effect of Radiation in Head and Neck Squamous Cell Carcinoma Models Journal Article
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Combined sonodynamic and antimetabolite therapy for the improved treatment of pancreatic cancer using oxygen loaded microbubbles as a delivery vehicle Journal Article
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Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins Journal Article
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Computational and Functional Analysis of the Virus-Receptor Interface Reveals Host Range Trade-Offs in New World Arenaviruses Journal Article
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Control of the Restriction Point by Rb and p21 Journal Article
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Controlling cellular packing and hypoxia in 3D tumor spheroids via DNA interactions. Journal Article
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DDX6 modulates P-body and stress granule assembly, composition, and docking. Journal Article
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DNA repair in response to anthracycline-DNA adducts: A role for both homologous recombination and nucleotide excision repair Journal Article
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DNA-Assembled Core-Satellite Upconverting-Metal-Organic Framework Nanoparticle Superstructures for Efficient Photodynamic Therapy Journal Article
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Deep in vivo two-photon imaging of blood vessels with a new dye encapsulated in pluronic nanomicelles Journal Article
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Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling Journal Article
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Design principles of drug combinations for chemotherapy Journal Article
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Design, synthesis, and biological evaluation of doxorubicin - Formaldehyde conjugates targeted to breast cancer cells Journal Article
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Design, synthesis, and preliminary evaluation of doxazolidine carbamates as prodrugs activated by carboxylesterases Journal Article
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Detecting Differential Transcription Factor Activity from ATAC-Seq Data Journal Article
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Differential Effects of Procaspase-3 Activating Compounds in the Induction of Cancer Cell Death Journal Article
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Dimensionality and Size Scaling of Coordinated Ca2+ Dynamics in MIN6 beta-cell Clusters Journal Article
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Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes Journal Article
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Distinct stages in stress granule assembly and disassembly Journal Article
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Does protein structure influence trypsin miscleavage? Journal Article
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Dosage and Temporal Thresholds in microRNA Proteomics Journal Article
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Doxazolidine induction of apoptosis by a topoisomerase II independent mechanism Journal Article
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Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA Journal Article
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EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism Journal Article
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Effect of covalent photoconjugation of affibodies to epidermal growth factor receptor (EGFR) on cellular quiescence Journal Article
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Effects of caffeine on the human circadian clock in vivo and in vitro Journal Article
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Efficient cellular uptake of click nucleic acid modified proteins Journal Article
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Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer Journal Article
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Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer. Journal Article
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Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature Journal Article
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Enzymatically degradable poly(ethylene glycol) hydrogels for the 3D culture and release of human embryonic stem cell derived pancreatic precursor cell aggregates Journal Article
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Enzyme Prodrug Therapy with Photo-Cross-Linkable Anti-EGFR Affibodies Conjugated to Upconverting Nanoparticles Journal Article
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Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling Journal Article
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Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling Journal Article
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Fully reduced granulin-B is intrinsically disordered and displays concentration-dependent dynamics Journal Article
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Functional PEG-peptide hydrogels to modulate local inflammation induced by the pro-inflammatory cytokine TNFα Journal Article
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Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma Journal Article
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Functional proteomic analysis of melanoma progression. Journal Article
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Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling Journal Article
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Functionalized Gold Nanorods for Thermal Ablation Treatment of Bladder Cancer Journal Article
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Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs Journal Article
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HIF1A Employs CDK8-Mediator to Stimulate RNAPII Elongation in Response to Hypoxia Journal Article
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Histone Deacetylase Inhibition Sensitizes PD1 Blockade-Resistant B-cell Lymphomas Journal Article
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Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model. Journal Article
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Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells Journal Article
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Hyaluronic Acid Hydrogels for Biomedical Applications Journal Article
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Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor Journal Article
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Identification of human intestinal carboxylesterase as the primary enzyme for activation of a doxazolidine carbamate prodrug Journal Article
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Improving reproducibility and sensitivity in identifying human proteins by shotgun proteomics Journal Article
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In Vivo Tibial Compression Decreases Osteolysis and Tumor Formation in a Human Metastatic Breast Cancer Model Journal Article
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Incorporating expression data in metabolic modeling: A case study of lactate dehydrogenase Journal Article
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Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma Journal Article
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Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells Journal Article
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Inhomogeneous background magnetic field in biological incubators is a potential confounder for experimental variability and reproducibility Journal Article
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Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo Journal Article
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Intermittent treatment of BRAFV600E melanoma cells delays resistance by adaptive resensitization to drug rechallenge Journal Article
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Irreversible APCCdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry Journal Article
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Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits Journal Article
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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis Journal Article
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Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor Journal Article
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Loss of p53 expression in cancer cells alters cell cycle response after inhibition o f exportin-1 but does not prevent cell death Journal Article
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Lung epithelial cells release ATP during ozone exposure: Signaling for cell survival Journal Article
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Mediator kinase inhibition further activates super-enhancer-associated genes in AML Journal Article
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Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling Journal Article
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Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers Journal Article
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Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness Journal Article
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Mps1 kinase regulates tumor cell viability via its novel role in mitochondria Journal Article
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Multicolour single-molecule tracking of mRNA interactions with RNP granules Journal Article
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Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition Journal Article
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Multifunctional nanoclusters of NaYF4:Yb3+,Er3+ upconversion nanoparticle and gold nanorod for simultaneous imaging and targeted chemotherapy of bladder cancer Journal Article
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Multiple cancers escape from multiple MAPK pathway inhibitors and use DNA replication stress signaling to tolerate aberrant cell cycles Journal Article
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Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis Journal Article
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Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers Journal Article
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NPEPPS Is a Druggable Driver of Platinum Resistance Journal Article
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Nanoparticle-Mediated Acoustic Cavitation Enables High Intensity Focused Ultrasound Ablation Without Tissue Heating Journal Article
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Nanoparticles Formed by Acoustic Destruction of Microbubbles and Their Utilization for Imaging and Effects on Therapy by High Intensity Focused Ultrasound Journal Article
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Negative Regulation of MAVS-Mediated Innate Immune Response by PSMA7 Journal Article
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Neurotoxic effects of TDP-43 overexpression in C-elegans Journal Article
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Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention Journal Article
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Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs Journal Article
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Overexpression of Mps1 in colon cancer cells attenuates the spindle assembly checkpoint and increases aneuploidy Journal Article
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PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells. Journal Article
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PEG-peptide hydrogels reveal differential effects of matrix microenvironmental cues on melanoma drug sensitivity Journal Article
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Pattern recognition receptors mediate pro-inflammatory effects of extracellular mitochondrial transcription factor A (TFAM) Journal Article
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Perfusion-guided sonopermeation of neuroblastoma: a novel strategy for monitoring and predicting liposomal doxorubicin uptake in vivo Journal Article
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Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties Journal Article
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Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells Journal Article
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Polycomb Repressive Complex 2 and H3K27me3 Cooperate with H3K9 Methylation To Maintain Heterochromatin Protein 1α at Chromatin Journal Article
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Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors Journal Article
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Potent and selective pyrazole-based inhibitors of B-Raf kinase Journal Article
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Preclinical Efficacy of a Carboxylesterase 2-Activated Prodrug of Doxazolidine Journal Article
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Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors Journal Article
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Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination Journal Article
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Programmed Cell Death Protein 5 Interacts with the Cytosolic Chaperonin Containing Tailless Complex Polypeptide 1 (CCT) to Regulate beta-Tubulin Folding Journal Article
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Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction Journal Article
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Prospects for the Use of Upconverting Nanoparticles as a Contrast Agent for Enumeration of Circulating Cells in vivo Journal Article
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Quantifying the Impact of Chimera MS/MS Spectra on Peptide Identification in Large-Scale Proteomics Studies Journal Article
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Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate Journal Article
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Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS Journal Article
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RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis Journal Article
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RNA partitioning into stress granules is based on the summation of multiple interactions Journal Article
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Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy Journal Article
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Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1 Journal Article
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Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells Journal Article
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Rational Design of Novel Allosteric EYA2 Inhibitors as Potential Therapeutics for Multiple Brain Cancers. Journal Article
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Reducing Tumour Hypoxia via Oral Administration of Oxygen Nanobubbles Journal Article
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Reduction of the Earth's Magnetic Field Inhibits Growth Rates of Model Cancer Cell Lines Journal Article
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Repositioning Antimicrobial Agent Pentamidine as a Disruptor of the Lateral Interactions of Transmembrane Domain 5 of EBV Latent Membrane Protein 1 Journal Article
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Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites. Journal Article
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RhoC promotes human melanoma invasion in a PI3K/Akt-dependent pathway Journal Article
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STAT3 Regulates Lytic Activation of Kaposi's Sarcoma-Associated Herpesvirus Journal Article
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Side Population Cells from Human Melanoma Tumors Reveal Diverse Mechanisms for Chemoresistance Journal Article
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Single cell analysis reveals multiple requirements for zinc in the mammalian Cell cycle Journal Article
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Single gold-bridged nanoprobes for identification of single point DNA mutations Journal Article
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Single-Agent Inhibition of Chk1 Is Antiproliferative in Human Cancer Cell Lines In Vitro and Inhibits Tumor Xenograft Growth In Vivo Journal Article
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Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines Journal Article
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Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells Journal Article
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Structural determinants for generating centromeric chromatin Journal Article
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Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion Journal Article
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Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells Journal Article
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Synthesis and Biological Activities of Azalamellarins Journal Article
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Synthesis and Biological Characterization of Protease-Activated Prodrugs of Doxazolidine Journal Article
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TRIM28 is a transcriptional activator of the mutant TERT in human bladder cancer Journal Article
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TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release Journal Article
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Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α Journal Article
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The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors Journal Article
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The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator Journal Article
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The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p Journal Article
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The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules Journal Article
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The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA Journal Article
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The photoreceptor protector zeaxanthin induces cell death in neuroblastoma cells Journal Article
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The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption Journal Article
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Three-Dimensional Mechanical Loading Modulates the Osteogenic Response of Mesenchymal Stem Cells to Tumor-Derived Soluble Signals Journal Article
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TiO2-Capped Gold Nanorods for Plasmon-Enhanced Production of Reactive Oxygen Species and Photothermal Delivery of Chemotherapeutic Agents Journal Article
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Transcription Factor Ets1 Cooperates with Estrogen Receptor alpha to Stimulate Estradiol-Dependent Growth in Breast Cancer Cells and Tumors Journal Article
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Transcriptome-Wide Comparison of Stress Granules and P-Bodies Reveals that Translation Plays a Major Role in RNA Partitioning Journal Article
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Tumor cell characterization and classification based on cellular specific membrane capacitance and cytoplasm conductivity Journal Article
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Two LXXLL motifs in the N terminus of Mps1 are required for Mps1 nuclear import during G(2)/M transition and sustained spindle checkpoint responses Journal Article
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Two-dimensional gel electrophoresis for the identification of signaling targets. Journal Article
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UV-C irradiation delays mitotic progression by recruiting Mps1 to kinetochores Journal Article
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Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins Journal Article
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Ultraviolet Photolysis of Chlorpyrifos: Developmental Neurotoxicity Modeled in PC12 Cells Journal Article
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Visualization of tyrosinase activity in melanoma cells by a BODIPY-based fluorescent probe Journal Article
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Wavelength Dependent UV Inactivation and DNA Damage of Adenovirus as Measured by Cell Culture Infectivity and Long Range Quantitative PCR Journal Article
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Wnt5a Directs Polarized Calcium Gradients by Recruiting Cortical Endoplasmic Reticulum to the Cell Trailing Edge Journal Article
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Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors Journal Article
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Zn2+ influx activates ERK and Akt signaling pathways Journal Article
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p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer Journal Article
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ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells Journal Article
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