The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator
Journal Article
Overview
publication date
- January 15, 2013
has subject area
- Biochemical Phenomena - Protein Binding
- Biochemical Phenomena - Proteolysis
- Biochemical Phenomena - Ubiquitination
- Biochemical Phenomena - Ubiquitination
- Carrier Proteins - Cyclin-Dependent Kinase 8
- Carrier Proteins - Mediator Complex
- Cell Cycle Proteins - Cyclin-Dependent Kinase 8
- Cell Line - Cell Line, Tumor
- Cell Line - HeLa Cells
- Cell Line, Transformed - HEK293 Cells
- Epithelial Cells - HEK293 Cells
- Epithelial Cells - HeLa Cells
- Gene Expression Regulation - Ubiquitination
- Gene Expression Regulation, Neoplastic
- Humans
- Metabolism - Protein Binding
- Metabolism - Proteolysis
- Metabolism - Ubiquitination
- Multiprotein Complexes - Cyclin-Dependent Kinase 8
- Multiprotein Complexes - Mediator Complex
- Nuclear Proteins - Cyclin-Dependent Kinase 8
- Nuclear Proteins - Mediator Complex
- Peptides - Cyclin-Dependent Kinase 8
- Peptides - Cyclin-Dependent Kinase 8
- Peptides - Mediator Complex
- Proline-Directed Protein Kinases - Cyclin-Dependent Kinase 8
- Proteins - Cyclin-Dependent Kinase 8
- Proteins - Cyclin-Dependent Kinase 8
- Proteins - Mediator Complex
- SKP Cullin F-Box Protein Ligases
- Tumor Cells, Cultured - Cell Line, Tumor
- Tumor Cells, Cultured - HeLa Cells
has restriction
- gold
Date in CU Experts
- September 3, 2013 2:59 AM
Full Author List
- Davis MA; Larimore EA; Fissel BM; Swanger J; Taatjes DJ; Clurman BE
author count
- 6
citation count
- 31
published in
- Genes and Development Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0890-9369
Digital Object Identifier (DOI)
Additional Document Info
start page
- 151
end page
- 156
volume
- 27
issue
- 2