Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling
Journal Article
Overview
publication date
- March 19, 2021
has subject area
- Biochemical Phenomena - DNA Replication
- Biochemical Phenomena - Signal Transduction
- Biochemical Phenomena - Transcriptome
- Biochemical Phenomena - Up-Regulation
- Cell Cycle Proteins - Cyclin-Dependent Kinase 2
- Cell Line - Cell Line, Tumor
- Cell Physiological Phenomena - Cell Proliferation
- Cell Physiological Phenomena - Signal Transduction
- DNA Damage
- DNA-Binding Proteins - Activating Transcription Factor 4
- Gene Expression - Transcriptome
- Gene Expression Regulation - Up-Regulation
- Genetic Phenomena - DNA Replication
- Genetic Structures - Transcriptome
- Growth - Cell Proliferation
- Humans
- Mutagenesis
- Neoplasms, Germ Cell and Embryonal - Melanoma
- Neoplasms, Nerve Tissue - Melanoma
- Nevi and Melanomas - Melanoma
- Peptides - Cyclin-Dependent Kinase 2
- Pharmacological Phenomena - Up-Regulation
- Proline-Directed Protein Kinases - Cyclin-Dependent Kinase 2
- Protein Kinase Inhibitors
- Proteins - Cyclin-Dependent Kinase 2
- Transcription Factors - Activating Transcription Factor 4
- Tumor Cells, Cultured - Cell Line, Tumor
has restriction
- gold
Date in CU Experts
- May 5, 2021 3:07 AM
Full Author List
- Yang C; Tian C; Hoffman TE; Jacobsen NK; Spencer SL
author count
- 5
citation count
- 37
published in
- Nature Communications Journal
Other Profiles
Electronic International Standard Serial Number (EISSN)
- 2041-1723
Digital Object Identifier (DOI)
Additional Document Info
volume
- 12
issue
- 1
number
- ARTN 1747