subject area of
- A Phosphoproteomic Comparison of B-RAF(V600E) and MKK1/2 Inhibitors in Melanoma Cells Journal Article
- Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation. Journal Article
- Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2 Journal Article
- Anti-EGFR Affibodies with Site-Specific Photo-Cross-Linker Incorporation Show Both Directed Target-Specific Photoconjugation and Increased Retention in Tumors Journal Article
- Dietary phytoestrogens present in soy dramatically increase cardiotoxicity in male mice receiving a chemotherapeutic tyrosine kinase inhibitor Journal Article
- Enzymes Photo-Cross-Linked to Live Cell Receptors Retain Activity and EGFR Inhibition after Both Internalization and Recycling Journal Article
- G alpha 12 and G alpha 13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells Journal Article
- Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma Journal Article
- Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase Journal Article
- Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases Journal Article
- Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics Journal Article
- Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling Journal Article
- Multifunctional bioscaffolds for 3D culture of melanoma cells reveal increased MMP activity and migration with BRAF kinase inhibition Journal Article
- PKM zeta Maintains Spatial, Instrumental, and Classically Conditioned Long-Term Memories Journal Article
- Photonic Crystal Kinase Biosensor Journal Article
- Potent and selective pyrazole-based inhibitors of B-Raf kinase Journal Article
- Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells Journal Article
- Single-Agent Inhibition of Chk1 Is Antiproliferative in Human Cancer Cell Lines In Vitro and Inhibits Tumor Xenograft Growth In Vivo Journal Article
- Slow Inhibition and Conformation Selective Properties of Extracellular Signal-Regulated Kinase 1 and 2 Inhibitors Journal Article
- Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells Journal Article
- The Case of the Disappearing Drug Target Journal Article
- The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors Journal Article
- p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer Journal Article