Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma
Journal Article
Overview
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Animals
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Biochemical Phenomena - DNA Repair
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Biochemical Phenomena - Peptide Chain Elongation, Translational
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Carcinoma - Squamous Cell Carcinoma of Head and Neck
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Cell Cycle
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Cell Line - Cell Line, Tumor
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Cell Physiological Phenomena - Dose-Response Relationship, Radiation
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Combined Modality Therapy - Chemoradiotherapy
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DNA Damage
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Drug Therapy - Chemoradiotherapy
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Female
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Genetic Phenomena - DNA Repair
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Head and Neck Neoplasms
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Head and Neck Neoplasms - Squamous Cell Carcinoma of Head and Neck
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Humans
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Investigative Techniques - Xenograft Model Antitumor Assays
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Macrocyclic Compounds - Peptides, Cyclic
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Metabolism - Peptide Chain Elongation, Translational
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Mice
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Neoplasm Transplantation - Xenograft Model Antitumor Assays
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Neoplasms - Neoplasm Recurrence, Local
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Neoplastic Stem Cells
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Pathologic Processes - Neoplasm Recurrence, Local
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Peptides - Peptides, Cyclic
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Physiological Phenomena - Dose-Response Relationship, Radiation
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Physiological Phenomena - Dose-Response Relationship, Radiation
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Protein Synthesis Inhibitors
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Radiation - Dose-Response Relationship, Radiation
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Radiologic Health - Dose-Response Relationship, Radiation
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Radiometry - Dose-Response Relationship, Radiation
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Radiotherapy - Chemoradiotherapy
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Radiotherapy Dosage
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Tumor Cells, Cultured - Cell Line, Tumor
Date in CU Experts
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January 14, 2020 12:39 PM
Full Author List
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Keysar SB; Gomes N; Miller B; Jackson BC; Le PN; Morton JJ; Reisinger J; Chimed T-S; Gomez KE; Nieto C
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