Ras proteins in developmental pattern formation in Caenorhabditis elegans and Drosophila. Journal Article uri icon



  • Recent studies of genetically isolated mutants in Caenorhabditis elegans and Drosophila have revealed ras functions in developmental pattern formation. The ras proteins act as genetic switches to determine cell fates between two alternative choices during C elegans vulval development (vulval versus hypodermal cells) and during Drosophila eye development (R7 versus cone cell). In both cases, ras proteins act downstream of a receptor tyrosine kinase in a signal transduction pathway that mediates cell-cell interactions. These genetic systems may allow the further elucidation of ras-mediated developmental regulatory pathways.

publication date

  • August 1, 1992

has subject area

Date in CU Experts

  • September 9, 2013 9:30 AM

Full Author List

  • Han M

author count

  • 1

Other Profiles

International Standard Serial Number (ISSN)

  • 1044-579X

Additional Document Info

start page

  • 219

end page

  • 228


  • 3


  • 4