Biochemistry
Overview
publication venue for
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The RNA-Binding Domain of hnRNP U Extends beyond the RGG/RG Motifs
2024
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Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance
2023
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Slow Dissociation from the PARP1-HPF1 Complex Drives Inhibitor Potency
2023
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Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance
2023
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A Closed Form Model for Molecular Ratchet-Type Chemically Induced Dimerization Modules
2023
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How to Recruit a Promiscuous Enzyme to Serve a New Function
2023
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An Extended DNA Binding Domain of the Estrogen Receptor Alpha Directly Interacts with RNAs in Vitro
2022
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Replication Protein A Utilizes Differential Engagement of Its DNA- Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes
2022
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The DNA-Binding High-Mobility Group Box Domain of Sox Family Proteins Directly Interacts with RNA In Vitro
2022
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Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases
2021
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Rosetta-Enabled Structural Prediction of Permissive Loop Insertion Sites in Proteins
2020
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Engineering of a Brighter Variant of the FusionRed Fluorescent Protein Using Lifetime Flow Cytometry and Structure-Guided Mutations
2020
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Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2
2020
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Feline Interleukin-31 Shares Overlapping Epitopes with the Oncostatin M Receptor and IL-31RA
2020
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Probing the Conformational Changes Associated with DNA Binding to PARP1
2020
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Nonspecific Binding of RNA to PARP1 and PARP2 Does Not Lead to Catalytic Activation
2019
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Correction to "Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation".
2019
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Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding
2019
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Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases
2018
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Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation
2018
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Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation.
2018
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Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila melanogaster and Caenorhabditis elegans
2017
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Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences
2017
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Extreme Dynamics in the BamA β-Barrel Seam
2017
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Protein Displacement by Herpes Helicase-Primase and the Key Role of UL42 during Helicase-Coupled DNA Synthesis by the Herpes Polymerase
2017
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Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-γ1 Protein
2017
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Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin
2017
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Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module
2016
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Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo
2016
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Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres
2016
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Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA
2016
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Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase
2015
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Polymerase and Exonuclease Activities in Herpes Simplex Virus Type 1 DNA Polymerase Are Not Highly Coordinated
2015
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Slow Inhibition and Conformation Selective Properties of Extracellular Signal-Regulated Kinase 1 and 2 Inhibitors
2015
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A Radical Intermediate in the Conversion of Pentachlorophenol to Tetrachlorohydroquinone by Sphingobium chlorophenolicum
2014
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Increasing and Decreasing the Ultrastability of Bacterial Chemotaxis Core Signaling Complexes by Modifying Protein-Protein Contacts
2014
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The interface between Escherichia coli elongation factor Tu and aminoacyl-tRNA.
2014
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The Structure and Specificity of the Type III Secretion System Effector NleC Suggest a DNA Mimicry Mechanism of Substrate Recognition
2014
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Partial Unfolding of a Monoclonal Antibody: Role of a Single Domain in Driving Protein Aggregation
2014
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New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography
2014
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Single-Molecule Studies Reveal a Hidden Key Step in the Activation Mechanism of Membrane-Bound Protein Kinase C-α
2014
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Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria
2014
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Structure, Function, and On-Off Switching of a Core Unit Contact between CheA Kinase and CheW Adaptor Protein in the Bacterial Chemosensory Array: A Disulfide Mapping and Mutagenesis Study
2013
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Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion
2013
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The PH Domain of Phosphoinositide-Dependent Kinase-1 Exhibits a Novel, Phospho-Regulated Monomer-Dimer Equilibrium with Important Implications for Kinase Domain Activation: Single-Molecule and Ensemble Studies
2013
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Defining a Key Receptor-CheA Kinase Contact and Elucidating Its Function in the Membrane-Bound Bacterial Chemosensory Array: A Disulfide Mapping and TAM-IDS Study
2013
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The 3.2 Å Resolution Structure of a Receptor:CheA:CheW Signaling Complex Defines Overlapping Binding Sites and Key Residue Interactions within Bacterial Chemosensory Arrays
2013
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The Orphan Protein Bis-γ-glutamylcystine Reductase Joins the Pyridine Nucleotide Disulfide Reductase Family
2013
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Synthetic Analogues of Nickel Superoxide Dismutase: A New Role for Nickel in Biology
2013
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Isolated Bacterial Chemosensory Array Possesses Quasi- and Ultrastable Components: Functional Links between Array Stability, Cooperativity, and Order
2012
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Duplex destabilization by four ribosomal DEAD-box proteins.
2012
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Single-Molecule Studies of the Lysine Riboswitch Reveal Effector-Dependent Conformational Dynamics of the Aptamer Domain
2012
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A Small Molecule Inhibitor of Pot1 Binding to Article Telomeric DNA
2012
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Hydrophobic Contributions to the Membrane Docking of Synaptotagmin 7 C2A Domain: Mechanistic Contrast between Isoforms 1 and 7
2012
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Single-Molecule Fluorescence Resonance Energy Transfer Shows Uniformity in TATA Binding Protein-Induced DNA Bending and Heterogeneity in Bending Kinetics
2012
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Pentachlorophenol Hydroxylase, a Poorly Functioning Enzyme Required for Degradation of Pentachlorophenol by Sphingobium chlorophenolicum
2012
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Assembly of Membrane-Bound Protein Complexes: Detection and Analysis by Single Molecule Diffusion
2012
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Initial- and Processive-Cut Products Reveal Cellobiohydrolase Rate Limitations and the Role of Companion Enzymes
2012
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The GRP1 PH Domain, Like the AKT1 PH Domain, Possesses a Sentry Glutamate Residue Essential for Specific Targeting to Plasma Membrane PI(3,4,5)P3
2011
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Comparative Hydrogen-Deuterium Exchange for a Mesophilic vs Thermophilic Dihydrofolate Reductase at 25 degrees C: Identification of a Single Active Site Region with Enhanced Flexibility in the Mesophilic Protein
2011
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Schizosaccharomyces pombe Protection of Telomeres 1 Utilizes Alternate Binding Modes To Accommodate Different Telomeric Sequences
2011
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B Family DNA Polymerases Asymmetrically Recognize Pyrimidines and Purines
2011
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Sequence-Specific Binding to Telomeric DNA Is Not a Conserved Property of the Cdc13 DNA Binding Domain
2011
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OS-FRET: A New One-Sample Method for Improved FRET Measurements
2011
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Regulation of Influenza RNA Polymerase Activity and the Switch between Replication and Transcription by the Concentrations of the vRNA 5′ End, the Cap Source, and the Polymerase
2010
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Multiple Turnovers of the Nicotino-Enzyme PdxB Require α-Keto Acids as Cosubstrates
2010
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Enhanced product stability in the hammerhead ribozyme.
2010
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Ultrafast Dynamics Show That the Theophylline and 3-Methylxanthine Aptamers Employ a Conformational Capture Mechanism for Binding Their Ligands
2010
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Parallel Multiplicative Target Screening against Divergent Bacterial Replicases: Identification of Specific Inhibitors with Broad Spectrum Potential
2010
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Mechanisms by Which Human DNA Primase Chooses To Polymerize a Nucleoside Triphosphate
2010
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Physical Instability of a Therapeutic Fc Fusion Protein: Domain Contributions to Conformational and Colloidal Stability
2009
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Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase
2009
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Herpes Simplex Virus-1 Helicase-Primase: Roles of Each Subunit in DNA Binding and Phosphodiester Bond Formation
2009
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Engineered Socket Study of Signaling through a Four-Helix Bundle: Evidence for a Yin-Yang Mechanism in the Kinase Control Module of the Aspartate Receptor
2009
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Interaction of Human DNA Polymerase alpha and DNA Polymerase I from Bacillus stearothermophilus with Hypoxanthine and 8-Oxoguanine Nucleotides
2009
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Ambivalent Incorporation of the Fluorescent Cytosine Analogues tC and tCo by Human DNA Polymerase α and Klenow Fragment
2009
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Nonadditivity in the Recognition of Single-Stranded DNA by the Schizosaccharomyces pombe Protection of Telomeres 1 DNA-Binding Domain, Pot1-DBD
2009
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The Core Signaling Proteins of Bacterial Chemotaxis Assemble To Form an Ultrastable Complex
2009
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Discrimination between Right and Wrong Purine dNTPs by DNA Polymerase I from Bacillus stearothermophilus
2009
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Thermal Domain Motions of CheA Kinase in Solution: Disulfide Trapping Reveals the Motional Constraints Leading to Trans-autophosphorylation
2009
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Identifying the Features of Purine dNTPs that Allow Accurate and Efficient DNA Replication by Herpes Simplex Virus I DNA Polymerase
2009
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Redox Regulation of SH2-Domain-Containing Protein Tyrosine Phosphatases by Two Backdoor Cysteines
2009
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Role of the 2-Amino Group of Purines during dNTP Polymerization by Human DNA Polymerase alpha
2009
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Differential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins.
2008
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Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain
2008
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Interaction of herpes primase with the sugar of a NTP
2008
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Effect of PIP2 binding on the membrane docking geometry of PKCα C2 domain:: An EPR site-directed spin-labeling and relaxation study
2008
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Catalytic diversity of extended hammerhead ribozymes.
2008
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Deciphering the mechanism of thermodynamic accommodation of telomeric oligonucleotide sequences by the Schizosaccharomyces pombe protection of telomeres 1 (Pot1pN) protein
2008
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A Trade-Off between Catalytic Power and Substrate Inhibition in TCHQ Dehalogenase
2008
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X-ray structure and microtubule interaction of the motor domain of neurospora crassa NcKin3, a kinesin with unusual processivity
2008
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Mass instability in isolated recombinant FixL heme domains of Bradyrhizobium japonicum
2008
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Structure of the conserved HAMP domain in an intact, membrane-bound chemoreceptor: A disulfide mapping study
2007
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Mutational analysis of the purine riboswitch aptamer domain
2007
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Why metabolic enzymes are essential or nonessential for growth of Escherichia coli k12 on glucose
2007
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Pre-Steady-State Kinetic Studies of the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase
2007
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Exploring the specificity of bacterial elongation factor Tu for different tRNAs.
2007
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Oxidation of methionine residues in recombinant human interleukin-1 receptor antagonist: Implications of conformational stability on protein oxidation kinetics
2007
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Mechanism of specific membrane targeting by C2 domains:: Localized pools of target lipids enhance Ca2+ affinity
2007
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Mechanism of the Severe Inhibition of Tetrachlorohydroquinone Dehalogenase by Its Aromatic Substrates
2007
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Efficient ligation of the Schistosoma hammerhead ribozyme
2007
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Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity
2007
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CheA kinase of bacterial chemotaxis: Chemical mapping of four essential docking sites
2006
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Temperature dependence of benzyl alcohol- and 8-anilinonaphthalene-1-sulfonate-induced aggregation of recombinant human interleukin-1 receptor antagonist
2006
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Metal ion dependence, thermodynamics, and kinetics for intramolecular docking of a GAAA tetraloop and receptor connected by a flexible linker
2006
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Identification of the determinants for the specific recognition of single-strand telomeric DNA by Cdc13
2006
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Herpes simplex virus 1 primase employs Watson-Crick hydrogen bonding to identify cognate nucleoside triphosphates
2005
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Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates.
2005
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Hammerheads derived from sTRSV show enhanced cleavage and ligation rate constants.
2005
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Ubiquitination of p21Cip1/WAF1 by SCFSkp2:: Substrate requirement and ubiquitination site selection
2005
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Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: Cysteine and disulfide scanning studies
2005
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Predicting the binding affinities of misacylated tRNAs for Thermus thermophilus EF-Tu.GTP.
2005
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A Mechanistic Investigation of the Thiol−Disulfide Exchange Step in the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase
2005
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Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching
2005
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Escherichia coli DbpA is a 3' --> 5' RNA helicase.
2005
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Comparison of the global structure and dynamics of native and unmodified tRNA
2005
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Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance.
2005
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Adaptation mechanism of the aspartate receptor: Electrostatics of the adaptation subdomain play a key role in modulating kinase activity
2005
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Call activation of the cPLA(2) C2 domain: Ordered binding of two Ca2+ ions with positive cooperativity
2004
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GRP1 pleckstrin homology domain: Activation parameters and novel search mechanism for rare target lipid
2004
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Evidence for increased local flexibility in psychrophilic alcohol dehydrogenase relative to its thermophilic homologue
2004
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Divergence of Function in the Thioredoxin Fold Suprafamily: Evidence for Evolution of Peroxiredoxins from a Thioredoxin-like Ancestor
2004
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Crystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain.: A key enzyme for lipid a modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance
2004
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Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates
2004
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Herpes simplex virus-1 primase: A polymerase with extraordinarily low fidelity
2004
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Herpes simplex virus-1 primase: a polymerase with extraordinarily low fidelity.
2004
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Contribution of the esterified amino acid to the binding of aminoacylated tRNAs to the ribosomal P- and A-sites.
2004
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The affinity of elongation factor Tu for an aminoacyl-tRNA is modulated by the esterified amino acid.
2004
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Microtubule-kinesin interface mutants reveal a site critical for communication
2004
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Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor
2004
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Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase
2004
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Histone -: DNA binding free energy cannot be measured in dilution-driven dissociation experiments
2004
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Membrane-docking loops of the cPLA2 C2 domain: Detailed structural analysis of the protein-membrane interface via site-directed spin-labeling
2003
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Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling.
2003
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Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I)
2003
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Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I).
2003
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Sequence-specific and 3 '-end selective single-strand DNA binding by the Oxytricha nova telomere end binding protein alpha subunit
2003
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High-pressure refolding of bikunin protein aggregates: efficacy and thermodynamics.
2003
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Pressure-induced aggregation of interleukin-1 receptor antagonist (IL-1ra): mechanism and thermodynamics
2003
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Stability of benzotriazole derivatives with free Cu, Zn, Co, and metal-containing enzymes: Binding and interaction with superoxide dismutase and vitamin B-12.
2003
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The Euplotes La motif protein p43 has properties of a telomerase-specific subunit
2003
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Site-directed mutagenesis reveals the thermodynamic requirements for single-stranded DNA recognition by the telomere-binding protein Cdc13
2003
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Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation
2003
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Motor domain mutation traps kinesin as a microtubule rigor complex
2003
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Role of a heterogeneous free state in the formation of a specific RNA-theophylline complex
2003
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C2 domain of protein kinase Cα:: Elucidation of the membrane docking surface by site-directed fluorescence and spin labeling
2003
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Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease α-synuclein fibrillogenesis
2003
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Cooperative binding of single-stranded telomeric DNA by the Pot1 protein of Schizosaccharomyces pombe
2002
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Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase
2002
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Synthesis of nucleotide analogues that potently and selectively inhibit human DNA primase
2002
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Structural and energetic analysis of metal ions essential to SRP signal recognition domain assembly
2002
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The global conformation of the hammerhead ribozyme determined using residual dipolar couplings
2002
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C2 domains of protein kinase C isoforms α, β, and γ:: Activation parameters and calcium stoichiometries of the membrane-bound state
2002
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Internal equilibrium of the hammerhead ribozyme is altered by the length of certain covalent cross-links
2002
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Aggregation of granulocyte colony stimulating factor under physiological conditions: Characterization and thermodynamic inhibition
2002
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Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling
2002
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Spectroscopic Characterization and O2 Reactivity of the Trinuclear Cu Cluster of Mutants of the Multicopper Oxidase Fet3p
2002
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The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting
2002
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Cooperative binding of ATP and RNA substrates to the DEAD/H protein DbpA
2002
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Cation charge and size selectivity of the C2 domain of cytosolic phospholipase A(2)
2002
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Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: Evidence for product-assisted translocation
2002
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Characterization of the Initial Steps in the Reductive Dehalogenation Catalyzed by Tetrachlorohydroquinone Dehalogenase
2002
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The Reaction Catalyzed by Tetrachlorohydroquinone Dehalogenase Does Not Involve Nucleophilic Aromatic Substitution
2002
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Inhibition of CMP-sialic acid transport into Golgi vesicles by nucleoside monophosphates
2001
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Energetics and affinity of the histone octamer for defined DNA sequences
2001
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The Tetrahymena ribozyme cleaves a 5′-methylene phosphonate monoester ∼102-fold faster than a normal phosphate diester:: Implications for enzyme catalysis of phosphoryl transfer reactions
2001
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Changes in protein conformational mobility upon activation of ERK2 as detected by hydrogen exchange.
2001
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A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity
2001
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C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity
2001
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Probing of metal-binding domains of RNA hairpin loops by laser-induced lanthanide(III) luminescence
2001
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Multiple folding pathways for the P4-P6 RNA domain
2000
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Active site dynamics in the lead-dependent ribozyme
2000
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Attractant regulation of the aspartate receptor-kinase complex: Limited cooperative interactions between receptors and effects of the receptor modification state
2000
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Mapping contacts between Escherichia coli alanyl tRNA synthetase and 2 ' hydroxyls using a complete tRNA molecule
2000
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Catalytic reaction pathway for the mitogen-activated protein kinase ERK2
2000
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Recruitment of a Double Bond Isomerase To Serve as a Reductive Dehalogenase during Biodegradation of Pentachlorophenol
2000
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Hammerhead cleavage of the phosphorodithioate linkage
2000
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Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA
2000
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Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome
2000
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Using phosphorothioate-substituted RNA to investigate the thermodynamic role of phosphates in a sequence specific RNA-protein complex
2000
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Catalytic reaction pathway for the mitogen-activated protein kinase ERK2
2000
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RNA tertiary folding monitored by fluorescence of covalently attached pyrene
1999
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Abasic template lesions are strong chain terminators for DNA primase but not for DNA polymerase alpha during the synthesis of new DNA strands
1999
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Interactions of DNA with human DNA primase monitored with photoactivatable cross-linking agents: Implications for the role of the p58 subunit
1999
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Human DNA primase: Anion inhibition, manganese stimulation, and their effects on in vitro start-site selection
1999
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Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: Cysteine and disulfide scanning studies
1999
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Energetics and cooperativity of tertiary hydrogen bonds in RNA structure
1999
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Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: Primase and the family X polymerases share significant sequence homology
1999
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Evidence that pcpA encodes 2,6-dichlorohydroquinone dioxygenase, the ring cleavage enzyme required for pentachlorophenol degradation in Sphingomonas chlorophenolica strain ATCC 39723
1999
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Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor
1999
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Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A(2)
1998
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Kinetic analysis of the RNA-dependent adenosinetriphosphatase activity of DbpA, an Escherichia coli DEAD protein specific for 23S ribosomal RNA
1998
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Thermodynamic dissection of the substrate-ribozyme interaction in the hammerhead ribozyme
1998
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The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
1998
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Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis
1998
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Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor
1998
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Circular substrates of the hammerhead ribozyme shift the internal equilibrium further toward cleavage
1998
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A semiconserved residue inhibits complex formation by stabilizing interactions in the free state of a theophylline-binding RNA
1998
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Binding of the protein kinase PKR to RNAs with secondary structure defects: Role of the tandem A-G mismatch and noncontiguous helixes
1998
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Participation of the 3‘-CCA of tRNA in the Binding of Catalytic Mg2+ Ions by Ribonuclease P
1998
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Euplotes telomerase: Evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation
1998
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Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme
1998
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Deuterium exchange mass spectrometry as a probe of protein kinase activation. Analysis of wild-type and constitutively active mutants of MAP kinase kinase-1
1998
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Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis
1997
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Ca2+-signaling cycle of a membrane-docking C2 domain
1997
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Optimizing the metal binding parameters of an EF-hand-like calcium chelation loop: Coordinating side chains play a more important tuning role than chelation loop flexibility
1997
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Hammerhead ribozymes with a faster cleavage rate
1997
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Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction
1997
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Eucaryotic DNA primase does not prefer to synthesize primers at pyrimidine rich DNA sequences when nucleoside triphosphates are present at concentrations found in whole cells
1997
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Redox-dependent structural changes in the nitrogenase P-cluster
1997
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A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme
1997
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Uncompetitive substrate inhibition and noncompetitive inhibition by 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole (UHDBT) and 2-n-Nonyl-4-hydroxyquinoline-N-oxide (NQNO) is observed for the cytochrome bo(3) complex: Implications for a Q(H-2)-loop proton translocation mechanism
1997
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A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate
1997
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Interdependent domains controlling the enzymatic activity of mitogen-activated protein kinase kinase 1
1996
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Mutations in the Tetrahymena ribozyme internal guide sequence: Effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity
1996
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Effects of protein stabilizing agents on thermal backbone motions: A disulfide trapping study
1996
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Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR
1996
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Biochemical and physicochemical properties of phosphorodithioate DNA
1996
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Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus
1996
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Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: Substitutions at the gateway position
1996
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Conformational switches involved in orchestrating the successive steps of group I RNA splicing
1996
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In vitro selection of RNA specifically cleaved by bacteriophage T4 RegB endonuclease
1996
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Kinetic tuning of the EF-Hand calcium binding motif: The gateway residue independently adjusts (I) barrier height and (II) equilibrium
1996
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Exocyclic amine of the conserved G center dot U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization
1996
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Exploration of the Relationship between Tetrachlorohydroquinone Dehalogenase and the Glutathione S-Transferase Superfamily
1996
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SELECTION AND CHARACTERIZATION OF RNAS REPLICATED BY Q-BETA REPLICASE
1995
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TEMPLATE RECOGNITION BY AN RNA-DEPENDENT RNA-POLYMERASE - IDENTIFICATION AND CHARACTERIZATION OF 2 RNA-BINDING SITES ON Q-BETA REPLICASE
1995
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DIVALENT METAL-IONS AND THE INTERNAL EQUILIBRIUM OF THE HAMMERHEAD RIBOZYME
1995
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SOLUTION STRUCTURE OF THE CUUG HAIRPIN LOOP - A NOVEL RNA TETRALOOP MOTIF
1995
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SOLUTION STRUCTURE OF BOVINE NEUTROPHIL BETA-DEFENSIN-12 - THE PEPTIDE FOLD OF THE BETA-DEFENSINS IS IDENTICAL TO THAT OF THE CLASSICAL DEFENSINS
1995
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THE ROLE OF 2'-HYDROXYL GROUPS IN AN RNA-PROTEIN INTERACTION
1995
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ARABINOFURANOSYL NUCLEOTIDES ARE NOT CHAIN-TERMINATORS DURING INITIATION OF NEW STRANDS OF DNA BY DNA-POLYMERASE ALPHA-PRIMASE
1995
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NEOMYCIN INHIBITION OF THE HAMMERHEAD RIBOZYME INVOLVES IONIC INTERACTIONS
1995
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MUTANTS OF THE BACTERIOPHAGE-MS2 COAT PROTEIN THAT ALTER ITS COOPERATIVE BINDING TO RNA
1995
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TRANSMEMBRANE SIGNALING BY THE ASPARTATE RECEPTOR - ENGINEERED DISULFIDES REVEAL STATIC REGIONS OF THE SUBUNIT INTERFACE
1995
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HIGH-AFFINITY SSDNA INHIBITORS OF THE REVERSE-TRANSCRIPTASE OF TYPE-1 HUMAN-IMMUNODEFICIENCY-VIRUS
1995
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EFFICIENT PROTEIN-FACILITATED SPLICING OF THE YEAST MITOCHONDRIAL BI5 INTRON
1995
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PROTON NMR AND STRUCTURAL FEATURES OF A 24-NUCLEOTIDE RNA HAIRPIN
1995
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IN-VITRO SELECTION OF RNA LIGANDS TO SUBSTANCE-P
1995
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A POSITIVE ENTROPY CHANGE FOR GUANOSINE BINDING AND FOR THE CHEMICAL STEP IN THE TETRAHYMENA RIBOZYME REACTION
1995
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HIGH-AFFINITY RNA LIGANDS TO ESCHERICHIA-COLI RIBOSOMES AND RIBOSOMAL-PROTEIN S1 - COMPARISON OF NATURAL AND UNNATURAL BINDING-SITES
1995
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LARGE-AMPLITUDE TWISTING MOTIONS OF AN INTERDOMAIN HINGE - A DISULFIDE TRAPPING STUDY OF THE GALACTOSE-GLUCOSE BINDING-PROTEIN
1995
-
ACYCLIC GUANOSINE ANALOGS INHIBIT DNA POLYMERASE-ALPHA, POLYMERASE-DELTA, POLYMERASE-EPSILON WITH VERY DIFFERENT POTENCIES AND HAVE UNIQUE MECHANISMS OF ACTION
1995
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DEFINING A SMALLER RNA SUBSTRATE FOR ELONGATION-FACTOR TU
1995
-
DETERMINATION OF V-MOS-CATALYZED PHOSPHORYLATION SITES AND AUTOPHOSPHORYLATION SITES ON MAP KINASE KINASE BY ESI/MS
1995
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THE INTERNAL EQUILIBRIUM OF THE HAMMERHEAD RIBOZYME REACTION
1995
-
CATALYSIS OF RNA CLEAVAGE BY A RIBOZYME DERIVED FROM THE GROUP-I INTRON OF ANABAENA PRE-TRNA(LEU)
1994
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REPLACEMENT OF THE CONSERVED G-CENTER-DOT-U WITH A G-C PAIR AT THE CLEAVAGE SITE OF THE TETRAHYMENA RIBOZYME DECREASES BINDING, REACTIVITY, AND FIDELITY
1994
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THE 2,6-DIAMINOPURINE RIBOSIDE-CENTER-DOT-5-METHYLISOCYTIDINE WOBBLE BASE-PAIR - AN ISOENERGETIC SUBSTITUTION FOR THE STUDY OF G-CENTER-DOT-U PAIRS IN RNA
1994
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Purification and Characterization of 4-Chlorobenzoyl CoA Dehalogenase from Arthrobacter sp. Strain 4-CB1
1994
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Rational Design of Self-Cleaving pre-tRNA-Ribonuclease P RNA Conjugates
1994
-
PROPERTIES OF AN IN-VITRO SELECTED PB2+ CLEAVAGE MOTIF
1994
-
SELECTION OF HIGH-AFFINITY RNA LIGANDS TO REVERSE-TRANSCRIPTASE - INHIBITION OF CDNA SYNTHESIS AND RNASE-H ACTIVITY
1994
-
ATTRACTANT-INDUCED AND DISULFIDE-INDUCED CONFORMATIONAL-CHANGES IN THE LIGAND-BINDING DOMAIN OF THE CHEMOTAXIS ASPARTATE RECEPTOR - A F-19 NMR-STUDY
1994
-
A KINETIC AND THERMODYNAMIC FRAMEWORK FOR THE HAMMERHEAD RIBOZYME REACTION
1994
-
TELOMERIC PROTEIN-DNA POINT CONTACTS IDENTIFIED BY PHOTO-CROSS-LINKING USING 5-BROMODEOXYURIDINE
1994
-
CALF THYMUS DNA-POLYMERASE ALPHA-PRIMASE - COMMUNICATION AND PRIMER-TEMPLATE MOVEMENT BETWEEN THE 2 ACTIVE-SITES
1994
-
TERTIARY INTERACTIONS WITH THE INTERNAL GUIDE SEQUENCE MEDIATE DOCKING OF THE P1 HELIX INTO THE CATALYTIC CORE OF THE TETRAHYMENA RIBOZYME
1993
-
USING CIRCULAR PERMUTATION ANALYSIS TO REDEFINE THE R17 COAT PROTEIN-BINDING SITE
1993
-
EVIDENCE FOR THE ROLE OF SOLVATED METAL HYDROXIDE IN THE HAMMERHEAD CLEAVAGE MECHANISM
1993
-
CHARACTERIZATION OF A G-QUARTET FORMATION REACTION PROMOTED BY THE BETA-SUBUNIT OF THE OXYTRICHA TELOMERE-BINDING PROTEIN
1993
-
NATURE OF THE RIBOSOMAL MESSENGER-RNA TRACK - ANALYSIS OF RIBOSOME-BINDING SITES CONTAINING DIFFERENT SEQUENCES AND SECONDARY STRUCTURES
1993
-
DNA POLYMERASE-EPSILON - APHIDICOLIN INHIBITION AND THE RELATIONSHIP BETWEEN POLYMERASE AND EXONUCLEASE ACTIVITY
1993
-
CONTRIBUTIONS OF 2'-HYDROXYL GROUPS OF THE RNA SUBSTRATE TO BINDING AND CATALYSIS BY THE TETRAHYMENA RIBOZYME - AN ENERGETIC PICTURE OF AN ACTIVE-SITE COMPOSED OF RNA
1993
-
THE IMPORTANCE OF BEING RIBOSE AT THE CLEAVAGE SITE IN THE TETRAHYMENA RIBOZYME REACTION
1993
-
SELF-SPLICING OF THE GROUP-I INTRON FROM ANABAENA PRE-TRANSFER-RNA - REQUIREMENT FOR BASE-PAIRING OF THE EXONS IN THE ANTICODON STEM
1993
-
IN-VITRO ANALYSIS OF TRANSLATIONAL RATE AND ACCURACY WITH AN UNMODIFIED TRANSFER-RNA
1993
-
AN INDEPENDENTLY FOLDING DOMAIN OF RNA TERTIARY STRUCTURE WITHIN THE TETRAHYMENA RIBOZYME
1993
-
Multiple magnesium ions in the ribonuclease P reaction mechanism
1993
-
NOVEL ION SPECIFICITY OF A CARBOXYLATE CLUSTER MG(II) BINDING-SITE - STRONG CHARGE SELECTIVITY AND WEAK SIZE SELECTIVITY
1993
-
MECHANISM OF CALF THYMUS DNA PRIMASE - SLOW INITIATION, RAPID POLYMERIZATION, AND INTELLIGENT TERMINATION
1993
-
KINETICS OF INTERMOLECULAR CLEAVAGE BY HAMMERHEAD RIBOZYMES
1992
-
NMR-STUDIES OF DEFENSIN ANTIMICROBIAL PEPTIDES .1. RESONANCE ASSIGNMENT AND SECONDARY STRUCTURE DETERMINATION OF RABBIT NP-2 AND HUMAN HNP-1
1992
-
NMR-STUDIES OF DEFENSIN ANTIMICROBIAL PEPTIDES .2. 3-DIMENSIONAL STRUCTURES OF RABBIT NP-2 AND HUMAN HNP-1
1992
-
DETERMINATION OF RECOGNITION NUCLEOTIDES FOR ESCHERICHIA-COLI PHENYLALANYL-TRANSFER RNA-SYNTHETASE
1992
-
INHIBITION OF DNA PRIMASE AND POLYMERASE-ALPHA BY ARABINOFURANOSYLNUCLEOSIDE TRIPHOSPHATES AND RELATED-COMPOUNDS
1992
-
RECOGNITION OF YEAST TRANSFER RNA(PHE) BY ITS COGNATE YEAST PHENYLALANYL-TRANSFER RNA-SYNTHETASE - AN ANALYSIS OF SPECIFICITY
1992
-
INVITRO SELECTION OF RNAS THAT UNDERGO AUTOLYTIC CLEAVAGE WITH PB2+
1992
-
In vitro selection of RNAs that undergo autolytic cleavage with Pb2+.
1992
-
RECOGNITION OF TERTIARY STRUCTURE IN TRANSFER-RNAS BY RH(PHEN)2PHI3+, A NEW REAGENT FOR RNA STRUCTURE-FUNCTION MAPPING
1992
-
Contributions of phylogenetically variable structural elements to the function of the ribozyme ribonuclease P
1992
-
ROLE OF DIVALENT METAL-IONS IN THE HAMMERHEAD RNA CLEAVAGE REACTION
1991
-
Mechanism of DNA polymerase .alpha. inhibition by aphidicolin
1991
-
QUANTITATING AND ENGINEERING THE ION SPECIFICITY OF AN EF-HAND-LIKE CA2+ BINDING-SITE
1991
-
SEQUENCE-SPECIFIC H-1-NMR ASSIGNMENTS, SECONDARY STRUCTURE, AND LOCATION OF THE CALCIUM-BINDING SITE IN THE 1ST EPIDERMAL GROWTH-FACTOR LIKE DOMAIN OF BLOOD-COAGULATION FACTOR-IX
1991
-
COMPARISON OF OPERATOR-SPECIFIC AND NONSPECIFIC DNA-BINDING OF THE LAMBDA-CI REPRESSOR - [KC1] AND PH EFFECTS
1991
-
OPEN CONFORMATION OF A SUBSTRATE-BINDING CLEFT - F-19 NMR-STUDIES OF CLEFT ANGLE IN THE D-GALACTOSE CHEMOSENSORY RECEPTOR
1991
-
A SPECIFIC, UV-INDUCED RNA PROTEIN CROSS-LINK USING 5-BROMOURIDINE-SUBSTITUTED RNA
1991
-
RIBOZYME-CATALYZED AND NONENZYMATIC REACTIONS OF PHOSPHATE DIESTERS - RATE EFFECTS UPON SUBSTITUTION OF SULFUR FOR A NONBRIDGING PHOSPHORYL OXYGEN ATOM
1991
-
F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .1. SUGAR BINDING YIELDS A GLOBAL STRUCTURAL-CHANGE
1991
-
F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .1. SUGAR BINDING YIELDS A GLOBAL STRUCTURAL-CHANGE
1991
-
F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .2. CA(II) BINDING YIELDS A LOCAL STRUCTURAL-CHANGE
1991
-
F-19 NMR-STUDIES OF THE D-GALACTOSE CHEMOSENSORY RECEPTOR .2. CA(II) BINDING YIELDS A LOCAL STRUCTURAL-CHANGE
1991
-
AUTONOMOUS FOLDING AND COENZYME BINDING OF THE EXCISED PYRIDOXAL 5'-PHOSPHATE BINDING DOMAIN OF ASPARTATE-AMINOTRANSFERASE FROM ESCHERICHIA-COLI
1991
-
ALTERNATIVE SECONDARY STRUCTURES IN THE 5' EXON AFFECT BOTH FORWARD AND REVERSE SELF-SPLICING OF THE TETRAHYMENA INTERVENING SEQUENCE RNA
1991
-
MECHANISM OF DNA-REPLICATION FIDELITY FOR 3 MUTANTS OF DNA-POLYMERASE-I - KLENOW FRAGMENT KF(EXO+), KF(POLA5), AND KF(EXO-)
1991
-
INHIBITION OF DNA PRIMASE BY 9-BETA-D-ARABINOFURANOSYLADENOSINE TRIPHOSPHATE
1991
-
COOPERATIVE BINDING OF R17 COAT PROTEIN TO RNA
1990
-
SEQUENCE REQUIREMENTS OF THE HAMMERHEAD RNA SELF-CLEAVAGE REACTION
1990
-
THE SELF-SPLICING RNA OF TETRAHYMENA IS TRAPPED IN A LESS ACTIVE CONFORMATION BY GEL PURIFICATION
1990
-
CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .1. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE COMPLEMENTARY TO THE ACTIVE-SITE
1990
-
CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .2. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE THAT FORMS A MISMATCH AT THE ACTIVE-SITE
1990
-
ROLE OF THE CRO REPRESSOR CARBOXY-TERMINAL DOMAIN AND FLEXIBLE DIMER LINKAGE IN OPERATOR AND NONSPECIFIC DNA-BINDING
1990
-
Reduction of the potent DNA polymerase III holoenzyme 3'----5' exonuclease activity by template-primer analogues.
1990
-
AN ULTRAVIOLET-INDUCIBLE ADENOSINE ADENOSINE CROSS-LINK REFLECTS THE CATALYTIC STRUCTURE OF THE TETRAHYMENA RIBOZYME
1990
-
CALCIUM(II) SITE SPECIFICITY - EFFECT OF SIZE AND CHARGE ON METAL-ION BINDING TO AN EF-HAND-LIKE SITE
1990
-
LEAD-CATALYZED CLEAVAGE OF YEAST TRANSFER RNAPHE MUTANTS
1990
-
ROLE OF THE TERTIARY NUCLEOTIDES IN THE INTERACTION OF YEAST PHENYLALANINE TRANSFER-RNA WITH ITS COGNATE SYNTHETASE
1990
-
THE MECHANISM OF KLENOW FRAGMENT MISINCORPORATION
1990
-
EARLY PHOTOLYSIS INTERMEDIATES OF THE ARTIFICIAL VISUAL PIGMENT 13-DEMETHYLRHODOPSIN
1990
-
IRON(II)-ETHYLENEDIAMINETETRAACETIC ACID-CATALYZED CLEAVAGE OF RNA AND DNA OLIGONUCLEOTIDES - SIMILAR REACTIVITY TOWARD SINGLE-STRANDED AND DOUBLE-STRANDED FORMS
1990
-
NANOSECOND PHOTOLYSIS OF RHODOPSIN - EVIDENCE FOR A NEW, BLUE-SHIFTED INTERMEDIATE
1990
-
SOLUTION STRUCTURES OF PROTEINS FROM NMR DATA AND MODELING - ALTERNATIVE FOLDS FOR NEUTROPHIL PEPTIDE-5
1989
-
LIMITED SAMPLING OF CONFORMATIONAL SPACE BY THE DISTANCE GEOMETRY ALGORITHM - IMPLICATIONS FOR STRUCTURES GENERATED FROM NMR DATA
1989
-
METAL-ION REQUIREMENTS FOR SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME
1989
-
STRUCTURE OF AN UNMODIFIED TRANSFER-RNA MOLECULE
1989
-
SOLUTION STRUCTURES OF ALPHA-CONOTOXIN-G1 DETERMINED BY TWO-DIMENSIONAL NMR-SPECTROSCOPY
1989
-
DETERMINATION OF RNA PROTEIN CONTACTS USING THIOPHOSPHATE SUBSTITUTIONS
1989
-
PROPERTIES OF THE TELOMERIC DNA-BINDING PROTEIN FROM OXYTRICHA-NOVA
1989
-
THERMAL-STABILITY OF RNA HAIRPINS CONTAINING A 4-MEMBERED LOOP AND A BULGE NUCLEOTIDE
1989
-
SPECIFIC RNA-BINDING BY Q-BETA COAT PROTEIN
1989
-
SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME - ENHANCED CLEAVAGE OF CERTAIN OLIGONUCLEOTIDE SUBSTRATES THAT FORM MISMATCHED RIBOZYME SUBSTRATE COMPLEXES
1988
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The dimer of the beta subunit of Escherichia coli DNA polymerase III holoenzyme is dissociated into monomers upon binding magnesium(II).
1988
-
Kinetics and thermodynamics of the interaction of 5-fluoro-2'-deoxyuridylate with thymidylate synthase.
1987
-
ROLE OF A BULGED-A RESIDUE IN A SPECIFIC RNA PROTEIN-INTERACTION
1987
-
Kinetic mechanism of DNA polymerase I (Klenow)
1987
-
Two-dimensional NMR studies of the antimicrobial peptide NP-5
1987
-
GUANOSINE BINDING REQUIRED FOR CYCLIZATION OF THE SELF-SPLICING INTERVENING SEQUENCE RIBONUCLEIC-ACID FROM TETRAHYMENA-THERMOPHILA
1987
-
RNA-BINDING SITE OF R17 COAT PROTEIN
1987
-
POLYMER-SUPPORTED RNA-SYNTHESIS AND ITS APPLICATION TO TEST THE NEAREST-NEIGHBOR MODEL FOR DUPLEX STABILITY
1986
-
Iron-sulfur centers in lactyl-CoA dehydratase
1986
-
SPECIFIC SUBSTITUTION INTO THE ANTICODON LOOP OF YEAST TYROSINE TRANSFER-RNA
1986
-
RIBOZYME INHIBITORS - DEOXYGUANOSINE AND DIDEOXYGUANOSINE ARE COMPETITIVE INHIBITORS OF SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR
1986
-
THE TETRAHYMENA INTERVENING SEQUENCE RIBONUCLEIC-ACID ENZYME IS A PHOSPHOTRANSFERASE AND AN ACID-PHOSPHATASE
1986
-
IDENTIFICATION OF THE FIBROBLAST GROWTH-FACTOR RECEPTOR OF SWISS-3T3 CELLS AND MOUSE SKELETAL-MUSCLE MYOBLASTS
1986
-
FREE-ENERGY CONTRIBUTIONS OF G.U AND OTHER TERMINAL MISMATCHES TO HELIX STABILITY
1986
-
STABILITY OF XGCGCP, GCGCYP, AND XGCGCYP HELIXES - AN EMPIRICAL ESTIMATE OF THE ENERGETICS OF HYDROGEN-BONDS IN NUCLEIC-ACIDS
1986
-
CALCIUM-BINDING TO COMPLEXES OF CALMODULIN AND CALMODULIN BINDING-PROTEINS
1985
-
Nucleoside and nucleotide inactivation of R17 coat protein: evidence for a transient covalent RNA-protein bond.
1985
-
Specific replacement of functional groups of uridine-33 in yeast phenylalanine transfer ribonucleic acid.
1985
-
Aminoacylation of anticodon loop substituted yeast tyrosine transfer RNA.
1985
-
NEW CHEMICAL METHODS FOR SYNTHESIZING DNA AND RNA
1985
-
REACTIONS OF THE INTERVENING SEQUENCE OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR - PH-DEPENDENCE OF CYCLIZATION AND SITE-SPECIFIC HYDROLYSIS
1985
-
SELF-SPLICING RNA
1985
-
Chemically induced dynamic nuclear polarization studies of guanosine in nucleotides, dinucleotides, and oligonucleotides
1984
-
BIOCHEMICAL-STUDIES USING SYNTHETIC DNA
1984
-
STUDIES ON GENE-CONTROL REGIONS .15. INTERACTION OF AD2+D2 PROTEIN AND SIMIAN VIRUS-40 LARGE T-ANTIGEN WITH THE LARGE TUMOR-ANTIGEN BINDING SITE-I
1984
-
Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III.
1983
-
Interaction of R17 coat protein with synthetic variants of its ribonucleic acid binding site.
1983
-
Mechanism of modulation of dopamine .beta.-monooxygenase by pH and fumarate as deduced from initial rate and primary deuterium isotope effect studies
1983
-
Kinetic and thermodynamic characterization of the R17 coat protein-ribonucleic acid interaction.
1983
-
Sequence-specific interaction of R17 coat protein with its ribonucleic acid binding site.
1983
-
Kinetics for exchange of the imino protons of the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix in complexes with the antibiotics netropsin and/or actinomycin
1983
-
FATE OF AN INTERVENING SEQUENCE RIBONUCLEIC-ACID - EXCISION AND CYCLIZATION OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID INTERVENING SEQUENCE INVIVO
1983
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IMMUNOAFFINITY PURIFICATION AND CHARACTERIZATION OF 5-[[[(IODOACETYL)AMINO]ETHYL]AMINO]NAPHTHALENE-1-SULFONIC ACID DERIVATIZED CALMODULIN
1983
-
Enzymatic synthesis of a 21-nucleotide coat protein binding fragment of R17 ribonucleic acid.
1982
-
Kinetics for exchange of imino protons in deoxyribonucleic acid, ribonucleic acid, and hybrid oligonucleotide helixes
1982
-
Specific interaction of anticodon loop residues with yeast phenylalanyl-tRNA synthetase.
1982
-
Enzymic and chemical structure mapping of mouse 28S ribosomal RNA-contacts in 5.8S ribosomal RNA
1982
-
Independent binding sites in mouse 5.8S ribosomal RNA for 28S ribosomal RNA
1982
-
Structural effects on the circular dichroism of ethidium ion nucleic acid complexes
1982
-
Reversal of T4 RNA ligase.
1982
-
Enzymatic replacement of the anticodon of yeast phenylalanine transfer ribonucleic acid.
1982
-
DETERMINATION OF THE FREE-ENERGY COUPLING FOR BINDING OF CALCIUM-IONS AND TROPONIN-I TO CALMODULIN
1982
-
INTERACTION OF A FLUORESCENT N-DANSYLAZIRIDINE DERIVATIVE OF TROPONIN-I WITH CALMODULIN IN THE ABSENCE AND PRESENCE OF CALCIUM
1982
-
UNUSUAL ZWITTERION OF D,L-BETA-CARBOXYASPARTIC ACID - PKA AND X-RAY CRYSTALLOGRAPHIC MEASUREMENTS
1982
-
Comparative study of ribonucleotides, deoxyribonucleotides, and hybrid oligonucleotide helixes by nuclear magnetic resonance
1981
-
ALKALINE GEL-ELECTROPHORESIS OF DEOXYRIBONUCLEIC-ACID PHOTOREACTED WITH TRIMETHYLPSORALEN - RAPID AND SENSITIVE DETECTION OF INTERSTRAND CROSS-LINKS
1981
-
PREPARATION OF A FLUORESCENT-LABELED DERIVATIVE OF CALMODULIN WHICH RETAINS ITS AFFINITY FOR CALMODULIN BINDING-PROTEINS
1981
-
Interaction of Escherichia coli host factor protein with Q beta ribonucleic acid.
1980
-
Interaction of Escherichia coli host factor protein with oligoriboadenylates.
1980
-
A METHOD FOR LINKING FLUORESCENT LABELS TO POLYNUCLEOTIDES - APPLICATION TO STUDIES OF RIBOSOME-RIBONUCLEIC ACID INTERACTIONS
1980
-
Bohr effect in Escherichia coli aspartate transcarbamylase. Linkages between substrate binding, proton binding, and conformational transitions.
1979
-
Involvement of the mature domain in the in vitro maturation of Bacillus subtilis precursor 5S ribosomal RNA
1978
-
Enzymatic oligoribonucleotide synthesis with T4 RNA ligase.
1978
-
Synthesis of modified nucleoside 3',5'-bisphosphates and their incorporation into oligoribonucleotides with T4 RNA ligase.
1978
-
3'-Phosphatase activity in T4 polynucleotide kinase.
1977
-
Involvement of precursor-specific segments in the in vitro maturation of Bacillus subtilis precursor 5S ribosomal RNA
1977
-
Electron microscopy of DNA crosslinked with trimethylpsoralen: a probe for chromatin structure
1977
-
Structure of the 5.8S RNA component of the 5.8S-28S ribosomal RNA junction complex
1977
-
STUDIES ON GENE CONTROL REGIONS .1. CHEMICAL SYNTHESIS OF LACTOSE OPERATOR DEOXYRIBONUCLEIC-ACID SEGMENTS
1977
-
STUDIES ON GENE CONTROL REGIONS .2. ENZYMATIC JOINING OF CHEMICALLY SYNTHESIZED LACTOSE OPERATOR DEOXYRIBONUCLEIC-ACID SEGMENTS
1977
-
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A LAMBDA-PSEUDO OPERATOR
1977
-
PARTIAL DENATURATION OF MOUSE DNA IN PREPARATIVE CSCL DENSITY GRADIENTS AT ALKALINE PH
1976
-
Renaturation of a multisubunit multiactivity enzyme complex: recovery of phage Qβ RNA replicase, EF-Tu, and EF-Ts activities after denaturation in urea
1976
-
Stepwise enzymatic oligoribonucleotide synthesis including modified nucleotides.
1975
-
A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant.
1974
-
Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.
1974
-
Circular dichroism study of nine species of transfer ribonucleic acid.
1972
-
Binding of complementary oligonucleotides to free and aminoacyl transfer ribonucleic acid synthetase bound transfer ribonucleic acid.
1972
-
Reactions of Nucleosides on Polymer Supports. Synthesis of Thymidylylthymidylylthymidine*
1967
Research
keywords
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0601 Biochemistry and Cell Biology, 1101 Medical Biochemistry and Metabolomics, 0304 Medicinal and Biomolecular Chemistry