Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA
Journal Article
Overview
publication date
- February 23, 2016
has subject area
- Acids, Acyclic - Foscarnet
- Acyclovir
- Antiviral Agents
- Binding Sites - Catalytic Domain
- Biochemical Phenomena - Kinetics
- Biochemical Phenomena - Molecular Structure
- Chemical Phenomena - Molecular Structure
- DNA - DNA, Single-Stranded
- DNA-Directed DNA Polymerase
- Deoxyribonucleases - Exodeoxyribonucleases
- Exonucleases - Exodeoxyribonucleases
- Genetic Structures - DNA, Single-Stranded
- Herpesvirus 1, Human
- Hydrolysis
- Mechanical Phenomena - Kinetics
- Models, Molecular
- Molecular Conformation - DNA, Single-Stranded
- Nucleic Acid Synthesis Inhibitors
- Organophosphonates - Foscarnet
- Protein Structural Elements - Catalytic Domain
- Recombinant Proteins
- Ribonucleotides
- Substrate Specificity
- Viral Proteins
has restriction
- green
Date in CU Experts
- February 18, 2016 9:26 AM
Full Author List
- Vashishtha AK; Kuchta RD
author count
- 2
citation count
- 19
published in
- Biochemistry Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0006-2960
Digital Object Identifier (DOI)
Additional Document Info
start page
- 1168
end page
- 1177
volume
- 55
issue
- 7