Physical Instability of a Therapeutic Fc Fusion Protein: Domain Contributions to Conformational and Colloidal Stability
Journal Article
Overview
publication date
- December 15, 2009
has subject area
- Biochemical Phenomena - Amino Acid Sequence
- Blood Proteins - Abatacept
- Blood Proteins - Immunoconjugates
- Blood Proteins - Immunoglobulin Fc Fragments
- Blood Proteins - Immunoglobulin Fc Fragments
- Chemistry Techniques, Analytical - Scattering, Radiation
- Complex Mixtures - Colloids
- Crystallography, X-Ray
- Electromagnetic Phenomena - Light
- Globulins - Abatacept
- Globulins - Immunoconjugates
- Globulins - Immunoglobulin Fc Fragments
- Globulins - Immunoglobulin Fc Fragments
- Humans
- Immunoproteins - Immunoglobulin Fc Fragments
- Immunoproteins - Immunoglobulin Fc Fragments
- Molecular Sequence Data
- Molecular Sequence Data - Amino Acid Sequence
- Noxae - Immunoconjugates
- Optical Phenomena - Light
- Peptide Fragments - Immunoglobulin Fc Fragments
- Pharmaceutical Preparations - Colloids
- Physical Phenomena - Scattering, Radiation
- Protein Conformation
- Protein Stability
- Protein Structure, Tertiary
- Radiation - Light
- Radiation, Nonionizing - Light
- Recombinant Fusion Proteins
has restriction
- green
Date in CU Experts
- September 3, 2013 2:48 AM
Full Author List
- Fast JL; Cordes AA; Carpenter JF; Randolph TW
author count
- 4
citation count
- 63
published in
- Biochemistry Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0006-2960
Digital Object Identifier (DOI)
Additional Document Info
start page
- 11724
end page
- 11736
volume
- 48
issue
- 49