subject area of
- A Radical Intermediate in the Conversion of Pentachlorophenol to Tetrachlorohydroquinone by Sphingobium chlorophenolicum Journal Article
- A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype Journal Article
- Accelerated Stability Studies of Abatacept Formulations: Comparison of Freeze-Thawing- and Agitation-Induced Stresses Journal Article
- Adsorption of Monoclonal Antibodies to Glass Microparticles Journal Article
- Banding of NMR-derived methyl order parameters: Implications for protein dynamics Journal Article
- Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation Journal Article
- Buffer-Dependent Fragmentation of a Humanized Full-Length Monoclonal Antibody Journal Article
- Chaperone Nap1 Shields Histone Surfaces Used in a Nucleosome and Can Put H2A-H2B in an Unconventional Tetrameric Form Journal Article
- Colloidal Instability Fosters Agglomeration of Subvisible Particles Created by Rupture of Gels of a Monoclonal Antibody Formed at Silicone Oil-Water Interfaces Journal Article
- Conjugation of Emtansine Onto Trastuzumab Promotes Aggregation of the Antibody-Drug Conjugate by Reducing Repulsive Electrostatic Interactions and Increasing Hydrophobic Interactions Journal Article
- Coupled Motion in Proteins Revealed by Pressure Perturbation Journal Article
- DEHP Nanodroplets Leached From Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum Journal Article
- Dense Poly(ethylene glycol) Brushes Reduce Adsorption and Stabilize the Unfolded Conformation of Fibronectin Journal Article
- Dissecting Protein Function: An Efficient Protocol for Identifying Separation-of-Function Mutations That Encode Structurally Stable Proteins Journal Article
- Distinct Aggregation Mechanisms of Monoclonal Antibody Under Thermal and Freeze-Thaw Stresses Revealed by Hydrogen Exchange Journal Article
- Effects of Surfaces and Leachables on the Stability of Biopharmaceuticals Journal Article
- Effects of solution conditions on methionine oxidation in albinterferon alfa-2b and the role of oxidation in its conformation and aggregation Journal Article
- Evaluation of Chemical Degradation of a Trivalent Recombinant Protein Vaccine Against Botulinum Neurotoxin by LysC Peptide Mapping and MALDI-TOF Mass Spectrometry Journal Article
- Freezing-Induced Perturbation of Tertiary Structure of a Monoclonal Antibody Journal Article
- Gelation of a Monoclonal Antibody at the Silicone Oil-Water Interface and Subsequent Rupture of the Interfacial Gel Results in Aggregation and Particle Formation Journal Article
- Increasing and Decreasing the Ultrastability of Bacterial Chemotaxis Core Signaling Complexes by Modifying Protein-Protein Contacts Journal Article
- Interactions between Hofmeister Anions and the Binding Pocket of a Protein Journal Article
- Investigations into the Fouling Mechanism of Parvovirus Filters During Filtration of Freeze-Thawed mAb Drug Substance Solutions Journal Article
- Isolated Bacterial Chemosensory Array Possesses Quasi- and Ultrastable Components: Functional Links between Array Stability, Cooperativity, and Order Journal Article
- MAVS Regulates Apoptotic Cell Death by Decreasing K48-Linked Ubiquitination of Voltage-Dependent Anion Channel 1 Journal Article
- Machine learning and statistical analyses for extracting and characterizing "fingerprints" of antibody aggregation at container interfaces from flow microscopy images Journal Article
- Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching Journal Article
- Microtubule Depolymerization by the Kinesin-8 Motor Kip3p: A Mathematical Model Journal Article
- Monoclonal Antibody Interactions With Micro- and Nanoparticles: Adsorption, Aggregation, and Accelerated Stress Studies Journal Article
- Multiplex Evolution of Antibody Fragments Utilizing a Yeast Surface Display Platform Journal Article
- Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes Journal Article
- Nitric oxide produced by cytochrome c oxidase helps stabilize HIF-1 alpha in hypoxic mammalian cells Journal Article
- On-Chip Acousto Thermal Shift Assay for Rapid and Sensitive Assessment of Protein Thermodynamic Stability Journal Article
- Partial Unfolding of a Monoclonal Antibody: Role of a Single Domain in Driving Protein Aggregation Journal Article
- Particles shed from syringe filters and their effects on agitation-induced protein aggregation Journal Article
- Physical Instability of a Therapeutic Fc Fusion Protein: Domain Contributions to Conformational and Colloidal Stability Journal Article
- Physical stability of albinterferon-alpha(2b) in aqueous solution: Effects of conformational stability and colloidal stability on aggregation Journal Article
- Polycomb Repressive Complex 2 and H3K27me3 Cooperate with H3K9 Methylation To Maintain Heterochromatin Protein 1α at Chromatin Journal Article
- Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues Journal Article
- Potential Inaccurate Quantitation and Sizing of Protein Aggregates by Size Exclusion Chromatography: Essential Need to Use Orthogonal Methods to Assure the Quality of Therapeutic Protein Products Journal Article
- Protein Nanoparticles Promote Microparticle Formation in Intravenous Immunoglobulin Solutions During Freeze-Thawing and Agitation Stresses Journal Article
- Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release Journal Article
- Reduced Subvisible Particle Formation in Lyophilized Intravenous Immunoglobulin Formulations Containing Polysorbate 20 Journal Article
- Regulatory approved monoclonal antibodies contain framework mutations predicted from human antibody repertoires Journal Article
- Response of a Concentrated Monoclonal Antibody Formulation to High Shear Journal Article
- Selective domain stabilization as a strategy to reduce fusion protein aggregation Journal Article
- Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution Journal Article
- Single molecule microscopy reveals mechanistic insight into RNA polymerase II preinitiation complex assembly and transcriptional activity Journal Article
- Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly Journal Article
- Stability of a Trivalent Recombinant Protein Vaccine Formulation Against Botulinum Neurotoxin During Storage in Aqueous Solution Journal Article
- Stability of p53 Homologs Journal Article
- Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding Journal Article
- Structural Basis of Selective Ubiquitination of TRF1 by SCFFbx4 Journal Article
- Structural Refinement of Glucagon for Therapeutic Use Journal Article
- The effects of excipients on protein aggregation during agitation: An interfacial shear rheology study Journal Article
- The interface between Escherichia coli elongation factor Tu and aminoacyl-tRNA. Journal Article
- The role of adjuvant in mediating antigen structure and stability Journal Article
- The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling Journal Article
- Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant Journal Article
- Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States Journal Article
- Type III secretion system effector proteins are mechanically labile Journal Article
- Urea Improves Stability of Inactivated Polio Vaccine Serotype 3 During Lyophilization and Storage in Dried Formulations Journal Article