Distinct Aggregation Mechanisms of Monoclonal Antibody Under Thermal and Freeze-Thaw Stresses Revealed by Hydrogen Exchange
Journal Article
Overview
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Biochemical Phenomena - Amino Acid Sequence
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Biochemical Phenomena - Complementarity Determining Regions
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Blood Proteins - Antibodies, Monoclonal
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Blood Proteins - Antibodies, Monoclonal, Humanized
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Blood Proteins - Bevacizumab
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Blood Proteins - Complementarity Determining Regions
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Blood Proteins - Complementarity Determining Regions
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Blood Proteins - Immunoglobulin Fab Fragments
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Chemical Phenomena - Freezing
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Chromatography, Gel
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Deuterium Exchange Measurement
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Ecological and Environmental Phenomena - Temperature
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Ecological and Environmental Phenomena - Temperature
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Environment and Public Health - Temperature
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Environment, Controlled - Temperature
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Globulins - Antibodies, Monoclonal
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Globulins - Antibodies, Monoclonal, Humanized
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Globulins - Bevacizumab
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Globulins - Complementarity Determining Regions
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Globulins - Complementarity Determining Regions
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Globulins - Immunoglobulin Fab Fragments
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Humans
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Immunoproteins - Antibodies, Monoclonal
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Immunoproteins - Antibodies, Monoclonal, Humanized
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Immunoproteins - Bevacizumab
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Immunoproteins - Complementarity Determining Regions
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Immunoproteins - Complementarity Determining Regions
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Immunoproteins - Immunoglobulin Fab Fragments
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Mass Spectrometry
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Molecular Sequence Data
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Molecular Sequence Data - Amino Acid Sequence
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Peptide Fragments - Complementarity Determining Regions
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Peptide Fragments - Immunoglobulin Fab Fragments
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Physical Phenomena - Freezing
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Protein Multimerization
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Protein Stability
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Receptors, Antigen, T-Cell - Complementarity Determining Regions
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Thermodynamics - Freezing
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Thermodynamics - Temperature
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Date in CU Experts
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September 4, 2015 2:15 AM
Full Author List
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Zhang A; Singh SK; Shirts MR; Kumar S; Fernandez EJ
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