Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity
Journal Article
Overview
publication date
- January 16, 2007
has subject area
- Binding Sites - Catalytic Domain
- Biochemical Phenomena - Amino Acid Sequence
- Biochemical Phenomena - Base Sequence
- Biochemical Phenomena - DNA Replication
- Biochemical Phenomena - Kinetics
- Biochemical Phenomena - Sequence Homology, Amino Acid
- DNA
- DNA Polymerase I
- Genetic Phenomena - DNA Replication
- Genetic Phenomena - Sequence Homology, Amino Acid
- Genetic Structures - Base Sequence
- Humans
- Hydrophobic and Hydrophilic Interactions
- In Vitro Techniques
- Magnetic Resonance Spectroscopy
- Mechanical Phenomena - Kinetics
- Models, Molecular
- Molecular Sequence Data
- Molecular Sequence Data - Amino Acid Sequence
- Molecular Sequence Data - Base Sequence
- Nucleic Acids, Nucleotides, and Nucleosides - Purine Nucleotides
- Protein Structural Elements - Catalytic Domain
- Purines - Purine Nucleotides
- Recombinant Proteins
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Substrate Specificity
has restriction
- green
Date in CU Experts
- September 6, 2013 4:49 AM
Full Author List
- Beckman J; Kincaid K; Hocek M; Spratt T; Engels J; Cosstick R; Kuchta RD
author count
- 7
citation count
- 37
published in
- Biochemistry Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0006-2960
Digital Object Identifier (DOI)
Additional Document Info
start page
- 448
end page
- 460
volume
- 46
issue
- 2