Mice, Mutant Strains - Mice, Knockout PubMed MeSh Term

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• Adam10 Is Essential for Early Embryonic Cardiovascular Development  Journal Article
• Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention  Journal Article
• Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy  Journal Article
• Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1  Journal Article
• Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling  Journal Article
• Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation  Journal Article
• A Cell-Intrinsic Role for Mst1 in Regulating Thymocyte Egress  Journal Article
• A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus  Journal Article
• A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model  Journal Article
• A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation  Journal Article
• A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction  Journal Article
• A skin microRNA promotes differentiation by repressing 'stemness'  Journal Article
• A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery  Journal Article
• ADAM10 is essential for proteolytic activation of Notch during thymocyte development  Journal Article
• Abcg2 labels multiple cell types in skeletal muscle and participates in muscle regeneration  Journal Article
• Acetylcholine-Stimulated [³H] GABA Release from Mouse Brain Synaptosomes is Modulated by α4β2 and α4α5β2 Nicotinic Receptor Subtypes  Journal Article
• Acute increases in intramuscular inflammatory cytokines are necessary for the development of mechanical hypersensitivity in a mouse model of musculoskeletal sensitization  Journal Article
• Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury  Journal Article
• Alcohol-induced sedation and synergistic interactions between alcohol and morphine: A key mechanistic role for Toll-like receptors and MyD88-dependent signaling  Journal Article
• Altered Entrainment to the Day/Night Cycle Attenuates the Daily Rise in Circulating Corticosterone in the Mouse  Journal Article
• Bacterial Stimulation of Toll-Like Receptor 4 Drives Macrophages To Hemophagocytose  Journal Article
• Behavior of mice aboard the International Space Station  Journal Article
• Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta  Journal Article
• Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland  Journal Article
• Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart  Journal Article
• Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb  Journal Article
• Central Representation of Postingestive Chemosensory Cues in Mice That Lack the Ability to Taste  Journal Article
• Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.  Journal Article
• Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice  Journal Article
• Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation  Journal Article
• Cytokine- and microbially induced sleep responses of interleukin-10 deficient mice  Journal Article
• DGCR8-dependent microRNA biogenesis is essential for skin development  Journal Article
• Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents  Journal Article
• Developmental Effects of Serotonin 1A Autoreceptors on Anxiety and Social Behavior  Journal Article
• Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling  Journal Article
• Diurnal variation in nicotine sensitivity in mice: Role of genetic background and melatonin  Journal Article
• Diurnal variation of lipopolysaccharide-induced alterations in sleep and body temperature of interleukin-6-deficient mice  Journal Article
• Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs  Journal Article
• Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse  Journal Article
• Dysregulation of mTOR signaling in fragile X syndrome.  Journal Article
• EVIDENCE THAT TRICYCLIC SMALL MOLECULES MAY POSSESS TOLL-LIKE RECEPTOR AND MYELOID DIFFERENTIATION PROTEIN 2 ACTIVITY  Journal Article
• Effect of early embryonic deletion of huntingtin from pyramidal neurons on the development and long-term survival of neurons in cerebral cortex and striatum  Journal Article
• Effects of dopamine β-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice  Journal Article
• Effects of i.c.v. administration of interleukin-1 on sleep and body temperature of interleukin-6-deficient mice  Journal Article
• Effects of major histocompatibility complex class II knockout on mouse bone mechanical properties during development  Journal Article
• Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice  Journal Article
• Effects of serotonergic activation by 5-hydroxytryptophan on sleep and body temperature of C57BL/6J and interleukin-6-deficient mice are dose and time related  Journal Article
• Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation  Journal Article
• Estrogens Mediate Cardiac Hypertrophy in a Stimulus-Dependent Manner  Journal Article
• Exercise Protects Against Myocardial Ischemia-Reperfusion Injury via Stimulation of β₃-Adrenergic Receptors and Increased Nitric Oxide Signaling: Role of Nitrite and Nitrosothiols  Journal Article
• Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration  Journal Article
• FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies  Journal Article
• Fecal corticosterone levels in RCAN1 mutant mice.  Journal Article
• Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons  Journal Article
• Formation of a full complement of cranial proprioceptors requires multiple neurotrophins  Journal Article
• Foxc1 reinforces quiescence in self-renewing hair follicle stem cells  Journal Article
• Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus.  Journal Article
• Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus  Journal Article
• Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons  Journal Article
• Generation of Protective T Cell-Independent Antiviral Antibody Responses in SCID Mice Reconstituted with Follicular or Marginal Zone B Cells  Journal Article
• Genetic Deletion of TrpV1 and TrpA1 Does Not Alter Avoidance of or Patterns of Brainstem Activation to Citric Acid in Mice  Journal Article
• Genetic approaches for understanding the role of serotonin receptors in mood and behavior  Journal Article
• Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice  Journal Article
• Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure  Journal Article
• Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32.  Journal Article
• Hypocretin Mediates Sleep and Wake Disturbances in a Mouse Model of Traumatic Brain Injury  Journal Article
• Immunocytochemical Organization and Sour Taste Activation in the Rostral Nucleus of the Solitary Tract of Mice  Journal Article
• In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements  Journal Article
• In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation  Journal Article
• Induction of Diabetes in the RIP-B7.1 Mouse Model Is Critically Dependent on TLR3 and MyD88 Pathways and Is Associated With Alterations in the Intestinal Microbiome  Journal Article
• Influence of Schizophrenia-Associated Gene Egr3 on Sleep Behavior and Circadian Rhythms in Mice  Journal Article
• Investigating clot-flow interactions by integrating intravital imaging with in silico modeling for analysis of flow, transport, and hemodynamic forces  Journal Article
• Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders  Journal Article
• KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development  Journal Article
• Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage  Journal Article
• LOSS OF SYNAPTOTAGMIN IV RESULTS IN A REDUCTION IN SYNAPTIC VESICLES AND A DISTORTION OF THE GOLGI STRUCTURE IN CULTURED HIPPOCAMPAL NEURONS  Journal Article
• Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection  Journal Article
• Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice  Journal Article
• Leptin increases skeletal muscle lipoprotein lipase and postprandial lipid metabolism in mice  Journal Article
• Lin28 promotes the proliferative capacity of neural progenitor cells in brain development  Journal Article
• Long-Lasting T Cell-Independent IgG Responses Require MyD88-Mediated Pathways and Are Maintained by High Levels of Virus Persistence  Journal Article
• Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice  Journal Article
• Loss of Grhl3 is correlated with altered cellular protrusions in the non-neural ectoderm during neural tube closure  Journal Article
• Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes  Journal Article
• Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance  Journal Article
• Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration  Journal Article
• MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3  Journal Article
• MAVS Regulates Apoptotic Cell Death by Decreasing K48-Linked Ubiquitination of Voltage-Dependent Anion Channel 1  Journal Article
• MECHANISM OF HYPERPHAGIA CONTRIBUTING TO OBESITY IN BRAIN-DERIVED NEUROTROPHIC FACTOR KNOCKOUT MICE  Journal Article
• Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors  Journal Article
• MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells  Journal Article
• Molecular and genetic approaches to studying exercise performance and adaptation  Journal Article
• Morphine activates neuroinflammation in a manner parallel to endotoxin  Journal Article
• Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs  Journal Article
• Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors  Journal Article
• Multiple knockout mouse models reveal lincRNAs are required for life and brain development  Journal Article
• Myosin heavy chains IIa and IId are functionally distinct in the mouse  Journal Article
• Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice  Journal Article
• Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains  Journal Article
• Neurotrophin receptor TrkB activation is not required for the postnatal survival of retinal ganglion cells in vivo  Journal Article
• Nicotine reverses hypofrontality in animal models of addiction and schizophrenia  Journal Article
• No evidence of a role of the β4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors.  Journal Article
• Norepinephrine transporter: A candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice  Journal Article
• Opposite-sex housing reactivates the declining GnRH system in aged transgenic male mice with FGF signaling deficiency  Journal Article
• Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity  Journal Article
• Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders  Journal Article
• Perlecan Knockdown Significantly Alters Extracellular Matrix Composition and Organization During Cartilage Development  Journal Article
• Plzf regulates limb and axial skeletal patterning  Journal Article
• Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains  Journal Article
• Programming human pluripotent stem cells into white and brown adipocytes  Journal Article
• Progranulin regulates neuronal outgrowth independent of Sortilin  Journal Article
• Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic  Journal Article
• Promiscuity rules? The dispensability of cyclin E and Cdk2.  Journal Article
• Quantitative functions of Argonaute proteins in mammalian development  Journal Article
• REDUCED Chrna7 EXPRESSION IN MICE IS ASSOCIATED WITH DECREASES IN HIPPOCAMPAL MARKERS OF INHIBITORY FUNCTION: IMPLICATIONS FOR NEUROPSYCHIATRIC DISEASES  Journal Article
• Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos  Journal Article
• Reduced ethanol-induced conditioned taste aversion and conditioned place preference in GIRK2 null mutant mice  Journal Article
• Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior.  Journal Article
• Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity.  Journal Article
• Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons  Journal Article
• Residual Chemoresponsiveness to Acids in the Superior Laryngeal Nerve in "Taste-Blind" (P2X2/P2X3 Double-KO) Mice  Journal Article
• Role of interleukin-6 in a glucan-induced model of granulomatous vasculitis  Journal Article
• Role of interleukin-6 in immune complex induced models of vascular injury  Journal Article
• SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice  Journal Article
• SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice  Journal Article
• SUSTAINED EXPRESSION OF BRAIN-DERIVED NEUROTROPHIC FACTOR IS REQUIRED FOR MAINTENANCE OF DENDRITIC SPINES AND NORMAL BEHAVIOR  Journal Article
• Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2^☆ receptor expression and clustering  Journal Article
• Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin  Journal Article
• Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice  Journal Article
• Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space  Journal Article
• Sleep-wake behavior and responses of interleukin-6-deficient mice to sleep deprivation  Journal Article
• Sleep-wake behavior and responses to sleep deprivation and immune challenge of protein kinase RNA-activated knockout mice.  Journal Article
• Sleep-wake behavior and responses to sleep deprivation of mice lacking both interleukin-1β receptor 1 and tumor necrosis factor-α receptor 1  Journal Article
• Smaller inner ear sensory epithelia in Neurog1 null mice are related to earlier hair cell cycle exit  Journal Article
• Spatial memory deficits and motor coordination facilitation in cGMP-dependent protein kinase type II-deficient mice.  Journal Article
• Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain  Journal Article
• Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication  Journal Article
• Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency  Journal Article
• Switching gears: translational mastery of transcription during memory formation.  Journal Article
• Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease.  Journal Article
• Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways  Journal Article
• Syndecan-3 and Notch cooperate in regulating adult myogenesis  Journal Article
• TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration  Journal Article
• The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis  Journal Article
• The Tug1 lncRNA locus is essential for male fertility  Journal Article
• The Aromatase Gene CYP19A1: Several Genetic and Functional Lines of Evidence Supporting a Role in Reading, Speech and Language  Journal Article
• The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling.  Journal Article
• The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α  Journal Article
• The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis  Journal Article
• The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice  Journal Article
• The p38α MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury  Journal Article
• The α6 nicotinic acetylcholine receptor subunit influences ethanol-induced sedation  Journal Article
• The β3 nicotinic receptor subunit:: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors  Journal Article
• The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption  Journal Article
• Towards the cloning of genes underlying murine QTLs  Journal Article
• Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate  Journal Article
• Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions  Journal Article
• Tuning Innate Immune Activation by Surface Texturing of Polymer Microparticles: The Role of Shape in Inflammasome Activation  Journal Article
• Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins  Journal Article
• Urocortin-1 and-2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits  Journal Article
• Variants of kappa-opioid receptor gene and mRNA in alcohol-preferring and alcohol-avoiding mice.  Journal Article
• Virion Assembly Factories in the Nucleus of Polyomavirus-Infected Cells  Journal Article
• cGMP-dependent protein kinase type II knockout mice exhibit working memory impairments, decreased repetitive behavior, and increased anxiety-like traits  Journal Article
• mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice.  Journal Article

broader concept

• Mice, Mutant Strains  PubMed MeSh Term