A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation
Journal Article
Overview
publication date
- February 24, 2015
has subject area
- Animal Population Groups - Mice, Knockout
- Animals
- Biochemical Phenomena - Enzyme Activation
- Biochemical Phenomena - Fluorescence Resonance Energy Transfer
- Biochemical Phenomena - MAP Kinase Signaling System
- Biological Factors - Transforming Growth Factor alpha
- Biological Factors - Transforming Growth Factor alpha
- Biophysical Phenomena - Fluorescence Resonance Energy Transfer
- Biosensing Techniques
- Cell Physiological Phenomena - MAP Kinase Signaling System
- Cytoskeleton
- Epidermal Cells - Keratinocytes
- Epithelial Cells
- Epithelial Cells - Keratinocytes
- Fluorometry - Fluorescence Resonance Energy Transfer
- Glycoconjugates - ADAM Proteins
- Glycoconjugates - ADAM17 Protein
- Metabolic Networks and Pathways - MAP Kinase Signaling System
- Metabolism - Enzyme Activation
- Metalloproteases - ADAM Proteins
- Metalloproteases - ADAM17 Protein
- Mice
- Mice - Mice, Knockout
- Mice, Mutant Strains - Mice, Knockout
- Peptides - Extracellular Signal-Regulated MAP Kinases
- Peptides - Transforming Growth Factor alpha
- Peptides - Transforming Growth Factor alpha
- Peptides - p38 Mitogen-Activated Protein Kinases
- Protein-Serine-Threonine Kinases - Extracellular Signal-Regulated MAP Kinases
- Protein-Serine-Threonine Kinases - p38 Mitogen-Activated Protein Kinases
- Proteins - ADAM Proteins
- Proteins - ADAM17 Protein
- Proteins - Extracellular Signal-Regulated MAP Kinases
- Proteins - Transforming Growth Factor alpha
- Proteins - Transforming Growth Factor alpha
- Proteins - p38 Mitogen-Activated Protein Kinases
has restriction
- green
Date in CU Experts
- March 4, 2015 4:41 AM
Full Author List
- Chapnick DA; Bunker E; Liu X
author count
- 3
citation count
- 17
published in
- Science Signaling Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1945-0877
Electronic International Standard Serial Number (EISSN)
- 1937-9145
Digital Object Identifier (DOI)
Additional Document Info
volume
- 8
issue
- 365
number
- ARTN rs1