Animal Population Groups - Mice, Knockout
PubMed MeSh Term
Overview
subject area of
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Adam10 Is Essential for Early Embryonic Cardiovascular Development Journal Article
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Atoh1 null mice show directed afferent fiber growth to undifferentiated ear sensory epithelia followed by incomplete fiber retention Journal Article
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Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy Journal Article
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Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1 Journal Article
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Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling Journal Article
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Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation Journal Article
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A Cell-Intrinsic Role for Mst1 in Regulating Thymocyte Egress Journal Article
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A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus Journal Article
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A basal-enriched microRNA is required for prostate tumorigenesis in a Pten knockout mouse model Journal Article
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A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation Journal Article
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A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction Journal Article
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A skin microRNA promotes differentiation by repressing 'stemness' Journal Article
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A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery Journal Article
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ADAM10 is essential for proteolytic activation of Notch during thymocyte development Journal Article
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Abcg2 labels multiple cell types in skeletal muscle and participates in muscle regeneration Journal Article
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Acetylcholine-Stimulated [3H] GABA Release from Mouse Brain Synaptosomes is Modulated by α4β2 and α4α5β2 Nicotinic Receptor Subtypes Journal Article
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Acute increases in intramuscular inflammatory cytokines are necessary for the development of mechanical hypersensitivity in a mouse model of musculoskeletal sensitization Journal Article
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Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury Journal Article
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Alcohol-induced sedation and synergistic interactions between alcohol and morphine: A key mechanistic role for Toll-like receptors and MyD88-dependent signaling Journal Article
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Altered Entrainment to the Day/Night Cycle Attenuates the Daily Rise in Circulating Corticosterone in the Mouse Journal Article
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Bacterial Stimulation of Toll-Like Receptor 4 Drives Macrophages To Hemophagocytose Journal Article
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Behavior of mice aboard the International Space Station Journal Article
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Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta Journal Article
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Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland Journal Article
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Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart Journal Article
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Cell type specific targeted intracellular delivery into muscle of a monoclonal antibody that binds myosin IIb Journal Article
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Central Representation of Postingestive Chemosensory Cues in Mice That Lack the Ability to Taste Journal Article
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Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome. Journal Article
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Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice Journal Article
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Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation Journal Article
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Cytokine- and microbially induced sleep responses of interleukin-10 deficient mice Journal Article
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DGCR8-dependent microRNA biogenesis is essential for skin development Journal Article
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Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents Journal Article
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Developmental Effects of Serotonin 1A Autoreceptors on Anxiety and Social Behavior Journal Article
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Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling Journal Article
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Diurnal variation in nicotine sensitivity in mice: Role of genetic background and melatonin Journal Article
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Diurnal variation of lipopolysaccharide-induced alterations in sleep and body temperature of interleukin-6-deficient mice Journal Article
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Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs Journal Article
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Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse Journal Article
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Dysregulation of mTOR signaling in fragile X syndrome. Journal Article
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EVIDENCE THAT TRICYCLIC SMALL MOLECULES MAY POSSESS TOLL-LIKE RECEPTOR AND MYELOID DIFFERENTIATION PROTEIN 2 ACTIVITY Journal Article
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Effect of early embryonic deletion of huntingtin from pyramidal neurons on the development and long-term survival of neurons in cerebral cortex and striatum Journal Article
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Effects of dopamine β-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice Journal Article
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Effects of i.c.v. administration of interleukin-1 on sleep and body temperature of interleukin-6-deficient mice Journal Article
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Effects of major histocompatibility complex class II knockout on mouse bone mechanical properties during development Journal Article
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Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice Journal Article
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Effects of serotonergic activation by 5-hydroxytryptophan on sleep and body temperature of C57BL/6J and interleukin-6-deficient mice are dose and time related Journal Article
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Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation Journal Article
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Estrogens Mediate Cardiac Hypertrophy in a Stimulus-Dependent Manner Journal Article
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Exercise Protects Against Myocardial Ischemia-Reperfusion Injury via Stimulation of β3-Adrenergic Receptors and Increased Nitric Oxide Signaling: Role of Nitrite and Nitrosothiols Journal Article
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Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration Journal Article
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FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies Journal Article
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Fecal corticosterone levels in RCAN1 mutant mice. Journal Article
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Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons Journal Article
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Formation of a full complement of cranial proprioceptors requires multiple neurotrophins Journal Article
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Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Journal Article
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Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus. Journal Article
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Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus Journal Article
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Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons Journal Article
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Generation of Protective T Cell-Independent Antiviral Antibody Responses in SCID Mice Reconstituted with Follicular or Marginal Zone B Cells Journal Article
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Genetic Deletion of TrpV1 and TrpA1 Does Not Alter Avoidance of or Patterns of Brainstem Activation to Citric Acid in Mice Journal Article
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Genetic approaches for understanding the role of serotonin receptors in mood and behavior Journal Article
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Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice Journal Article
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Grainyhead-like 2 downstream targets act to suppress epithelial-to-mesenchymal transition during neural tube closure Journal Article
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Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32. Journal Article
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Hypocretin Mediates Sleep and Wake Disturbances in a Mouse Model of Traumatic Brain Injury Journal Article
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Immunocytochemical Organization and Sour Taste Activation in the Rostral Nucleus of the Solitary Tract of Mice Journal Article
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In Vivo Characterization of Linc-p21 Reveals Functional cis-Regulatory DNA Elements Journal Article
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In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation Journal Article
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Induction of Diabetes in the RIP-B7.1 Mouse Model Is Critically Dependent on TLR3 and MyD88 Pathways and Is Associated With Alterations in the Intestinal Microbiome Journal Article
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Influence of Schizophrenia-Associated Gene Egr3 on Sleep Behavior and Circadian Rhythms in Mice Journal Article
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Investigating clot-flow interactions by integrating intravital imaging with in silico modeling for analysis of flow, transport, and hemodynamic forces Journal Article
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Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders Journal Article
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KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development Journal Article
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Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage Journal Article
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LOSS OF SYNAPTOTAGMIN IV RESULTS IN A REDUCTION IN SYNAPTIC VESICLES AND A DISTORTION OF THE GOLGI STRUCTURE IN CULTURED HIPPOCAMPAL NEURONS Journal Article
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Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection Journal Article
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Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice Journal Article
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Leptin increases skeletal muscle lipoprotein lipase and postprandial lipid metabolism in mice Journal Article
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Lin28 promotes the proliferative capacity of neural progenitor cells in brain development Journal Article
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Long-Lasting T Cell-Independent IgG Responses Require MyD88-Mediated Pathways and Are Maintained by High Levels of Virus Persistence Journal Article
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Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice Journal Article
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Loss of Grhl3 is correlated with altered cellular protrusions in the non-neural ectoderm during neural tube closure Journal Article
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Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes Journal Article
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Loss of desmin leads to impaired voluntary wheel running and treadmill exercise performance Journal Article
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Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle progenitor cell homeostasis improving muscle regeneration Journal Article
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MAVS Promotes Inflammasome Activation by Targeting ASC for K63-Linked Ubiquitination via the E3 Ligase TRAF3 Journal Article
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MAVS Regulates Apoptotic Cell Death by Decreasing K48-Linked Ubiquitination of Voltage-Dependent Anion Channel 1 Journal Article
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MECHANISM OF HYPERPHAGIA CONTRIBUTING TO OBESITY IN BRAIN-DERIVED NEUROTROPHIC FACTOR KNOCKOUT MICE Journal Article
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Melatonin administration alters nicotine preference consumption via signaling through high-affinity melatonin receptors Journal Article
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MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells Journal Article
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Molecular and genetic approaches to studying exercise performance and adaptation Journal Article
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Morphine activates neuroinflammation in a manner parallel to endotoxin Journal Article
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Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs Journal Article
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Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors Journal Article
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Multiple knockout mouse models reveal lincRNAs are required for life and brain development Journal Article
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Myosin heavy chains IIa and IId are functionally distinct in the mouse Journal Article
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Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice Journal Article
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Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains Journal Article
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Neurotrophin receptor TrkB activation is not required for the postnatal survival of retinal ganglion cells in vivo Journal Article
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Nicotine reverses hypofrontality in animal models of addiction and schizophrenia Journal Article
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No evidence of a role of the β4 subunit of the nicotinic acetylcholine receptor in alcohol-related behaviors. Journal Article
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Norepinephrine transporter: A candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice Journal Article
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Opposite-sex housing reactivates the declining GnRH system in aged transgenic male mice with FGF signaling deficiency Journal Article
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Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity Journal Article
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Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders Journal Article
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Perlecan Knockdown Significantly Alters Extracellular Matrix Composition and Organization During Cartilage Development Journal Article
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Plzf regulates limb and axial skeletal patterning Journal Article
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Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains Journal Article
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Programming human pluripotent stem cells into white and brown adipocytes Journal Article
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Progranulin regulates neuronal outgrowth independent of Sortilin Journal Article
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Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic Journal Article
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Promiscuity rules? The dispensability of cyclin E and Cdk2. Journal Article
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Quantitative functions of Argonaute proteins in mammalian development Journal Article
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REDUCED Chrna7 EXPRESSION IN MICE IS ASSOCIATED WITH DECREASES IN HIPPOCAMPAL MARKERS OF INHIBITORY FUNCTION: IMPLICATIONS FOR NEUROPSYCHIATRIC DISEASES Journal Article
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Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos Journal Article
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Reduced ethanol-induced conditioned taste aversion and conditioned place preference in GIRK2 null mutant mice Journal Article
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Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Journal Article
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Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity. Journal Article
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Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons Journal Article
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Residual Chemoresponsiveness to Acids in the Superior Laryngeal Nerve in "Taste-Blind" (P2X2/P2X3 Double-KO) Mice Journal Article
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Role of interleukin-6 in a glucan-induced model of granulomatous vasculitis Journal Article
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Role of interleukin-6 in immune complex induced models of vascular injury Journal Article
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SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice Journal Article
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SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice Journal Article
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SUSTAINED EXPRESSION OF BRAIN-DERIVED NEUROTROPHIC FACTOR IS REQUIRED FOR MAINTENANCE OF DENDRITIC SPINES AND NORMAL BEHAVIOR Journal Article
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Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2☆ receptor expression and clustering Journal Article
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Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin Journal Article
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Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice Journal Article
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Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space Journal Article
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Sleep-wake behavior and responses of interleukin-6-deficient mice to sleep deprivation Journal Article
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Sleep-wake behavior and responses to sleep deprivation and immune challenge of protein kinase RNA-activated knockout mice. Journal Article
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Sleep-wake behavior and responses to sleep deprivation of mice lacking both interleukin-1β receptor 1 and tumor necrosis factor-α receptor 1 Journal Article
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Smaller inner ear sensory epithelia in Neurog1 null mice are related to earlier hair cell cycle exit Journal Article
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Spatial memory deficits and motor coordination facilitation in cGMP-dependent protein kinase type II-deficient mice. Journal Article
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Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain Journal Article
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Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication Journal Article
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Striated muscle gene therapy for the treatment of lipoprotein lipase deficiency Journal Article
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Switching gears: translational mastery of transcription during memory formation. Journal Article
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Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease. Journal Article
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Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways Journal Article
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Syndecan-3 and Notch cooperate in regulating adult myogenesis Journal Article
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TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration Journal Article
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The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis Journal Article
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The Tug1 lncRNA locus is essential for male fertility Journal Article
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The Aromatase Gene CYP19A1: Several Genetic and Functional Lines of Evidence Supporting a Role in Reading, Speech and Language Journal Article
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The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling. Journal Article
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The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α Journal Article
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The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis Journal Article
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The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice Journal Article
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The p38α MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury Journal Article
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The α6 nicotinic acetylcholine receptor subunit influences ethanol-induced sedation Journal Article
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The β3 nicotinic receptor subunit:: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors Journal Article
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The β3 subunit of the nicotinic acetylcholine receptor: Modulation of gene expression and nicotine consumption Journal Article
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Towards the cloning of genes underlying murine QTLs Journal Article
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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate Journal Article
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Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions Journal Article
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Tuning Innate Immune Activation by Surface Texturing of Polymer Microparticles: The Role of Shape in Inflammasome Activation Journal Article
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Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins Journal Article
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Urocortin-1 and-2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits Journal Article
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Variants of kappa-opioid receptor gene and mRNA in alcohol-preferring and alcohol-avoiding mice. Journal Article
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Virion Assembly Factories in the Nucleus of Polyomavirus-Infected Cells Journal Article
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cGMP-dependent protein kinase type II knockout mice exhibit working memory impairments, decreased repetitive behavior, and increased anxiety-like traits Journal Article
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mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient mice. Journal Article
broader concept