Research in Liu laboratory is focused on the discovery of cellular mechanism that control cell proliferation and identify novel anti-cancer reagents and anti-neurodegenerative agents. We study cell signaling pathways that are critical for cancer cell proliferation and Parkinson's diseases.
keywords
Cell signaling, systems biology, anti-cancer drug development
BCHM 4740 - Biochemistry of Gene Transmission, Expression and Regulation
Primary Instructor
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Fall 2021 / Fall 2022
Covers biosynthesis and function of macromolecules including DNA, RNA and proteins; molecular basis of replication, transcription and translation; biochemistry of subcellular systems; signaling and regulation of gene expression in eukaryotes; and special topics. Formerly CHEM 4740. Same as BCHM 5740.
BCHM 4761 - Biochemistry Laboratory
Primary Instructor
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Spring 2021
Two 4-hour periods per week. Introduction to modern biochemical techniques. Topics include enzymology, spectrophotometry, electrophoresis, multi-step protein purification, recombinant DNA techniques and molecular cloning. Formerly CHEM 4761.
BCHM 5740 - Biochemistry of Gene Transmission, Expression and Regulation
Primary Instructor
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Fall 2021
Covers biosynthesis and function of macromolecules including DNA, RNA and proteins; molecular basis of replication, transcription and translation; biochemistry of subcellular systems; signaling and regulation of gene expression in eukaryotes; and special topics. Formerly CHEM 5740. Same as BCHM 4740.
BCHM 5780 - Advanced General Biochemistry 2
Primary Instructor
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Spring 2020
Lect. Detailed consideration of contemporary topics in biochemistry, including protein structure (primary, secondary, tertiary, and quaternary), methods of structure determination and prediction, protein folding (kinetics, thermodynamics, denaturation, and renaturation), and protein dynamics (internal motions and methods of analysis). Formerly CHEM 5781.
BCHM 5821 - Special Topics in Signaling and Cell Regulation
Primary Instructor
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Fall 2019 / Spring 2020 / Fall 2020 / Fall 2021 / Spring 2022 / Fall 2022 / Spring 2023 / Fall 2024
Lect. Reviews and evaluates literature on subjects of current interest in signal transduction transcription, cell cycle progression, and cell regulation. Primarily for graduate level presentation of special topics by students, faculty, and research staff. May be repeated up to 5 total credit hours. Department consent required. Formerly CHEM 5821.
BCHM 6951 - Master's Thesis
Primary Instructor
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Spring 2022
Students are not admitted for the master's degree but may be transferred to the MS plan if they are unable to meet the demands of the PhD program.
CHEM 5801 - Advanced Signal Transduction and Cell Cycle Regulation
Primary Instructor
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Spring 2018
Lect. Advanced discussion of current research and literature in signal transduction, including ligands, receptors, and intracellular signaling pathways, as well as control on transcription, chromatin structure, DNA replication, mitosis, and cell cycle progression. Recommended prerequisites: CHEM 5771 and CHEM 5781 and MCDB 5210 or MCDB 5220. Formerly CHEM 5801.
CHEM 5821 - Special Topics in Signaling and Cell Regulation
Primary Instructor
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Spring 2018 / Fall 2018 / Spring 2019
Lect. Reviews and evaluates literature on subjects of current interest in signal transduction transcription, cell cycle progression, and cell regulation. Primarily for graduate level presentation of special topics by students, faculty, and research staff. May be repeated up to 5 total credit hours. Department consent required. Formerly CHEM 5821.
MCDB 6000 - Introduction to Laboratory Methods
Primary Instructor
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Fall 2024
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.
