Largazole and Its Derivatives Selectively Inhibit Ubiquitin Activating Enzyme (E1)
Journal Article
Overview
publication date
- January 18, 2012
has subject area
- Adenine
- Animals
- Azoles - Thiazoles
- Biochemical Phenomena - Enzyme Activation
- Biochemical Phenomena - Molecular Structure
- Biochemical Phenomena - Ubiquitination
- Biochemical Phenomena - Ubiquitination
- Cell Cycle Proteins - Cyclin-Dependent Kinase Inhibitor p27
- Cell Line
- Cell Line, Transformed - HEK293 Cells
- Chemical Phenomena - Molecular Structure
- Chemistry Techniques, Analytical - Electrophoresis, Polyacrylamide Gel
- DNA-Binding Proteins - Telomeric Repeat Binding Protein 1
- Electrochemical Techniques - Electrophoresis, Polyacrylamide Gel
- Epithelial Cells - HEK293 Cells
- Gene Expression Regulation - Ubiquitination
- Gene Transfer Techniques - Transfection
- Green Fluorescent Proteins
- Humans
- Immunologic Techniques - Immunoblotting
- Macrocyclic Compounds - Depsipeptides
- Metabolism - Enzyme Activation
- Metabolism - Ubiquitination
- Molecular Probe Techniques - Immunoblotting
- Nuclear Proteins - Telomeric Repeat Binding Protein 1
- Organic Chemicals - Thiazoles
- Peptides - Cyclin-Dependent Kinase Inhibitor p27
- Peptides - Depsipeptides
- Pharmacological Phenomena - Dose-Response Relationship, Drug
- Proteins - Cyclin-Dependent Kinase Inhibitor p27
- Recombination, Genetic - Transfection
- Toxicological Phenomena - Dose-Response Relationship, Drug
- Tumor Suppressor Proteins - Cyclin-Dependent Kinase Inhibitor p27
- Ubiquitin
- Ubiquitin-Activating Enzymes
has restriction
- gold
Date in CU Experts
- September 6, 2013 4:49 AM
Full Author List
- Ungermannova D; Parker SJ; Nasveschuk CG; Wang W; Quade B; Zhan G; Kuchta RD; Phillips AJ; Liu X
author count
- 9
citation count
- 59
published in
- PLoS One Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1932-6203
Digital Object Identifier (DOI)
Additional Document Info
volume
- 7
issue
- 1
number
- ARTN e29208