Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers
Journal Article
Overview
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Azoles - Thiazoles
Biochemical Phenomena - Acetylation
Biochemical Phenomena - Enhancer Elements, Genetic
Biochemical Phenomena - Histone Code
Biochemical Phenomena - Promoter Regions, Genetic
Carrier Proteins - Histones
Cell Line
Cell Line, Transformed
Cytostatic Agents
Genetic Structures - Enhancer Elements, Genetic
Genetic Structures - Histone Code
Genetic Structures - Promoter Regions, Genetic
Genome
Histone Deacetylase Inhibitors
Histone Deacetylases
Macrocyclic Compounds - Depsipeptides
Metabolism - Acetylation
Nuclear Proteins - Histones
Nucleoproteins - Histones
Oncogenes
Organic Chemicals - Thiazoles
Organic Chemistry Phenomena - Acetylation
Peptides - Depsipeptides
Pharmacological Phenomena - Dose-Response Relationship, Drug
RNA Polymerase II
RNA, Messenger
Regulatory Elements, Transcriptional - Enhancer Elements, Genetic
Regulatory Elements, Transcriptional - Promoter Regions, Genetic
Toxicological Phenomena - Dose-Response Relationship, Drug
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Date in CU Experts
December 22, 2017 12:12 PM
Full Author List
Sanchez GJ; Richmond PA; Bunker EN; Karman SS; Azofeifa J; Garnett AT; Xu Q; Wheeler GE; Toomey CM; Zhang Q
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