The Stitzel laboratory is interested in the molecular and physiological mechanisms leading to nicotine dependence and co-morbid psychiatric conditions such as schizophrenia and ADHD. Current studies include: 1) identifying novel genes that influence nicotine consumption; 2) determining the functional consequence and mechanism of action of genetic variants known to impact drug seeking behavior; 3) establishing mechanisms through which nicotine exposure in utero increases the offspring’s risk for nicotine dependence, ADHD and schizophrenia; and 4) understanding the mechanisms through which nicotine withdrawal disrupts sleep and how this information can lead to better treatments for smoking cessation.
IPHY 4200 - Physiological Genetics and Genomics
Primary Instructor
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Spring 2018 / Spring 2019 / Spring 2020 / Spring 2021 / Spring 2022 / Spring 2024
Covers fundamental concepts in molecular genetics/genomics with physiological applications. Topics include structure and function of nucleic acids, genome structure, genetic and genomic research tools, methods for identifying disease-causing mutations, regulation of gene expression, pharmacogenetics, gene therapy and ethical issues in modern genomics. First course of a 3-course series recommended for IBG students. Includes a recitation section. Same as IPHY 5200.
IPHY 4870 - Honors Thesis
Primary Instructor
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Spring 2018
An opportunity for students enrolled in the IPHY Honors program to earn academic credit for working on their thesis. Twenty-five hours of work is required for each hour of academic credit given. Consult for faculty mentor for approval. Recommended prerequisites: IPHY 3700; and IPHY 4850 (taken concurrently).
IPHY 5200 - Physiological Genetics and Genomics
Primary Instructor
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Spring 2018 / Spring 2019 / Spring 2020 / Spring 2021 / Spring 2022 / Spring 2024
Covers fundamental concepts in molecular genetics/genomics with physiological applications. Topics include structure and function of nucleic acids, genome structure, genetic and genomic research tools, methods for identifying disease-causing mutations, regulation of gene expression, pharmacogenetics, gene therapy and ethical issues in modern genomics. First course of a 3-course series recommended for IBG students. Includes a recitation section. Same as IPHY 4200 and PSYC 5200.
IPHY 6010 - Seminar
Primary Instructor
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Fall 2019
Presents special topics in integrative physiology. May be repeated up to 15 total credits.
IPHY 6840 - Research Project
Primary Instructor
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Spring 2019
Involves a scholarly investigation of a selected topic using literature and/or experimental techniques. Advisor required. May be repeated up to 3 total credit hours.
PSYC 5200 - Physiological Genetics and Genomics
Primary Instructor
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Spring 2018 / Spring 2019 / Spring 2020 / Spring 2021 / Spring 2024
Covers fundamental concepts in molecular genetics/genomics with physiological applications. Topics include structure and function of nucleic acids, genome structure, genetic and genomic research tools, methods for identifying disease-causing mutations, regulation of gene expression, pharmacogenetics, gene therapy and ethical issues in modern genomics. First course of a 3-course series recommended for IBG students. Includes a recitation section. Same as IPHY 4200 and IPHY 5200.
PSYC 7102 - Seminar: Behavioral Genetics
Primary Instructor
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Fall 2019
Intensive study of selected topics in behavioral genetics. Emphasizes recent research. Attention to both human and animal studies. May be repeated up to 12 total credit hours. Instructor consent required for students outside of the Behavioral, Psychiatric, and Statistical Genetics program.
