Nuclear Proteins - Telomerase PubMed MeSh Term

Overview

subject area of

• 3 ' terminal diversity of MRP RNA and other human noncoding RNAs revealed by deep sequencing  Journal Article
• Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting  Journal Article
• Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle  Journal Article
• TERT promoter mutations and telomerase reactivation in urothelial cancer  Journal Article
• A bulged stem tethers Est1p to telomerase RNA in budding yeast  Journal Article
• A miniature yeast telomerase RNA functions in vivo and reconstitutes activity in vitro  Journal Article
• A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity  Journal Article
• A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression  Journal Article
• A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity  Journal Article
• A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity  Journal Article
• ANALYSIS OF THE STRUCTURE OF TETRAHYMENA NUCLEAR RNAS IN-VIVO - TELOMERASE RNA, THE SELF-SPLICING RIBOSOMAL-RNA INTRON, AND U2 SNRNA  Journal Article
• Aging Is Associated with a Proapoptotic Endothelial Progenitor Cell Phenotype  Journal Article
• Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes  Journal Article
• Allele-specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates withTERTexpression in multiple cancers  Journal Article
• Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin  Journal Article
• Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe  Journal Article
• Beginning to understand the end of the chromosome  Journal Article
• CST does not evict elongating telomerase but prevents initiation by ssDNA binding  Journal Article
• Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita  Journal Article
• Contributions of the TEL-patch Amino Acid Cluster on TPP1 to Telomeric DNA Synthesis by Human Telomerase  Journal Article
• Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase  Journal Article
• Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance  Journal Article
• Dissecting Protein Function: An Efficient Protocol for Identifying Separation-of-Function Mutations That Encode Structurally Stable Proteins  Journal Article
• Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: Evidence for product-assisted translocation  Journal Article
• Engineering cis-telomerase RNAs that add telomeric repeats to themselves  Journal Article
• Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants  Journal Article
• Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction.  Journal Article
• Euplotes telomerase: Evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation  Journal Article
• Expression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase  Journal Article
• Filling in the blanks: how the C-strand catches up to the G-strand at replicating telomeres using CST  Journal Article
• Finding the end: recruitment of telomerase to telomeres  Journal Article
• Functional interaction between telomere protein TPP1 and telomerase  Journal Article
• Global expression changes resulting from loss of telomeric DNA in fission yeast  Journal Article
• Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro  Journal Article
• Human POT1 facilitates telomere elongation by telomerase  Journal Article
• Human aging and CD31⁺ T-cell number, migration, apoptotic susceptibility, and telomere length  Journal Article
• Human telomerase: biogenesis, trafficking, recruitment, and activation  Journal Article
• Identification of human TERT elements necessary for telomerase recruitment to telomeres  Journal Article
• Inhibition of Telomerase Recruitment and Cancer Cell Death  Journal Article
• Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects  Journal Article
• Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13p  Journal Article
• Inventory of telomerase components in human cells reveals multiple subpopulations of hTR and hTERT  Journal Article
• Investigating the role of the Est3 protein in yeast telomere replication  Journal Article
• Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP  Journal Article
• Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres  Journal Article
• Long Noncoding RNAs: Molecular Modalities to Organismal Functions  Journal Article
• Low abundance of telomerase in yeast: Implications for telomerase haploinsufficiency  Journal Article
• Many disease-associated variants of hTERT retain high telomerase enzymatic activity  Journal Article
• Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers  Journal Article
• Method for determining RNA 3' ends and application to human telomerase RNA  Journal Article
• Modulation of telomerase activity by telomere DNA-binding proteins in Oxytricha  Journal Article
• Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance  Journal Article
• Mutation in TERT separates processivity from anchor-site function  Journal Article
• Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers  Journal Article
• Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model  Journal Article
• N-terminal domain of yeast telomerase reverse transcriptase: Recruitment of Est3p to the telomerase complex  Journal Article
• Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention  Journal Article
• PARN Modulates Y RNA Stability and Its 3′-End Formation  Journal Article
• POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation  Journal Article
• Polyadenylation of telomerase RNA in budding yeast  Journal Article
• Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita  Journal Article
• Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination  Journal Article
• Protection of telomeres by the Ku protein in fission yeast  Journal Article
• Protein-RNA interaction restricts telomerase from running through the stop sign  Journal Article
• Purification of telomerase from Euplotes aediculatus: Requirement of a primer 3' overhang  Journal Article
• RNA as a flexible scaffold for proteins: Yeast telomerase and beyond  Journal Article
• RNA recognition by the DNA end-binding Ku heterodimer  Journal Article
• Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1  Journal Article
• Reconstitution of a telomeric replicon organized by CST  Journal Article
• Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity  Journal Article
• Replication Timing of Human Telomeres Is Chromosome Arm-Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization  Journal Article
• Reverse transcriptase motifs in the catalytic subunit of telomerase  Journal Article
• Reversing time: Origin of telomerase  Journal Article
• Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization  Journal Article
• Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines  Journal Article
• Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis.  Journal Article
• SnapShot: Telomeres and Telomerase  Journal Article
• Soluble domains of telomerase reverse transcriptase identified by high-throughput screening  Journal Article
• Structure of Est3 reveals a bimodal surface with differential roles in telomere replication  Journal Article
• Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection  Journal Article
• Studying telomere replication by Q-CO-FISH: the effect of telomestatin, a potent G-quadruplex ligand  Journal Article
• Switching human telomerase on and off with hPOT1 protein in vitro  Journal Article
• TRIM28 is a transcriptional activator of the mutant TERT in human bladder cancer  Journal Article
• Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase  Journal Article
• Telomerase and Telomere-Associated Proteins: Structural Insights into Mechanism and Evolution  Journal Article
• Telomerase and chromosome end maintenance  Journal Article
• Telomerase and the chromosome end replication problem  Journal Article
• Telomerase and the maintenance of chromosome ends  Journal Article
• Telomerase catalytic subunit homologs from fission yeast and human  Journal Article
• Telomerase in Bladder Cancer: Back to a Better Future?  Journal Article
• Telomerase is a true reverse transcriptase. A review  Journal Article
• Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax  Journal Article
• Telomere biology disorders: time for moving towards the clinic?  Journal Article
• Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells  Journal Article
• Telorneres: Not all breaks are equal  Journal Article
• Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants  Journal Article
• Tetrahymena telomerase is active as a monomer  Journal Article
• The Euplotes La motif protein p43 has properties of a telomerase-specific subunit  Journal Article
• The Cech Symposium: A celebration of 25 years of ribozymes, 10 years of TERT, and 60 years of Tom  Journal Article
• The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro  Journal Article
• The POT1-TPP1 telomere complex is a telomerase processivity factor  Journal Article
• The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis  Journal Article
• The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity  Journal Article
• The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers  Journal Article
• Three ever shorter telomere (EST) genes are dispensable for in vitro yeast telomerase activity  Journal Article
• Triple-helix structure in telomerase RNA contributes to catalysis  Journal Article
• Two modes of survival of fission yeast without telomerase  Journal Article
• Yeast telomerase RNA: A flexible scaffold for protein subunits  Journal Article
• Yeast telomerase is specialized for C/A-rich RNA templates  Journal Article
• dGTP-dependent processivity and possible template switching of Euplotes telomerase  Journal Article

broader concept

• Nuclear Proteins - Poly-ADP-Ribose Binding Proteins  PubMed MeSh Term