Brain, Behavior, and Immunity Journal

Overview

publication venue for

• Sleep-wake behavior and responses to sleep deprivation and immune challenge of protein kinase RNA-activated knockout mice. 2024
• Use of adeno-associated viruses for transgenic modulation of microglia structure and function: A review of technical considerations and challenges 2024
• Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats 2024
• Voluntary wheel running prevents formation of membrane attack complexes and myelin degradation after peripheral nerve injury 2024
• Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP:TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of COVID-19 2023
• Intrathecal non-viral interleukin-10 gene therapy ameliorates neuropathic pain as measured by both classical static allodynia and a novel supra-spinally mediated pain assay, the Two-Arm Rodent Somatosensory (TARS) task 2023
• Mycobacterium vaccae protects against glucocorticoid resistance resulting from combined physical and psychosocial trauma in mice 2023
• Immunization with a heat-killed preparation of Mycobacterium vaccae NCTC 11659 enhances auditory-cued fear extinction in a stress-dependent manner 2023
• Interleukin-6 receptor antagonists in immunopsychiatry: Can they lead to increased interleukin-6 in the central nervous system (CNS) and worsening psychiatric symptoms? 2022
• SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: Evidence of PAMP-like properties 2022
• Ruminiclostridium 5, Parabacteroides distasonis, and bile acid profile are modulated by prebiotic diet and associate with facilitated sleep/clock realignment after chronic disruption of rhythms 2021
• Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury 2021
• Mentorship Memoriam: Mark Laudenslager, PhD 2021
• Perceived stress is linked to heightened biomarkers of inflammation via diurnal cortisol in a national sample of adults 2021
• Toll -like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain 2021
• Comparing the effects of two different strains of mycobacteria, Mycobacterium vaccae NCTC 11659 and M. vaccae ATCC 15483, on stress-resilient behaviors and lipid-immune signaling in rats 2021
• Acute stress induces the rapid and transient induction of caspase-1, gasdermin D and release of constitutive IL-1 beta protein in dorsal hippocampus 2020
• Targeted interleukin-10 plasmid DNA therapy in the treatment of osteoarthritis: Toxicology and pain efficacy assessments 2020
• Acute stress induces chronic neuroinflammatory, microglial and behavioral priming: A role for potentiated NLRP3 inflammasome activation 2020
• Effects of immunization with heat-killed Mycobacterium vaccae on autism spectrum disorder-like behavior and epileptogenesis in a rat model of comorbid autism and epilepsy 2020
• Subcutaneous Mycobacterium vaccae promotes resilience in a mouse model of chronic psychosocial stress when administered prior to or during psychosocial stress 2020
• Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain 2019
• Treatment with a heat-killed preparation of Mycobacterium vaccae after fear conditioning enhances fear extinction in the fear-potentiated startle paradigm 2019
• Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats 2019
• Glucocorticoids mediate stress induction of the alarmin HMGB1 and reduction of the microglia checkpoint receptor CD200R1 in limbic brain structures 2019
• Intranasal Mycobacterium vaccae administration prevents stress-induced aggravation of dextran sulfate sodium (DSS) colitis 2019
• Evidence that preimmunization with a heat-killed preparation of Mycobacterium vaccae reduces corticotropin-releasing hormone mRNA expression in the extended amygdala in a fear-potentiated startle paradigm 2019
• A single peri-sciatic nerve administration of the adenosine 2A receptor agonist ATL313 produces long-lasting anti-allodynia and anti-inflammatory effects in male rats 2019
• Negative and positive affect as predictors of inflammation: Timing matters. 2018
• Immunization with Mycobacterium vaccae induces an anti-inflammatory milieu in the CNS: Attenuation of stress-induced microglial priming, alarmins and anxiety-like behavior 2018
• Stress and aging act through common mechanisms to elicit neuroinflammatory priming 2018
• Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats 2018
• A novel platform for in vivo detection of cytokine release within discrete brain regions 2018
• Neuroinflammatory priming to stress is differentially regulated in male and female rats 2018
• Stress disinhibits microglia via down-regulation of CD200R: A mechanism of neuroinflammatory priming 2018
• Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A_2A receptor agonists 2018
• Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking 2018
• Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm 2017
• Growing literature but limited evidence: A systematic review regarding prebiotic and probiotic interventions for those with traumatic brain injury and/or posttraumatic stress disorder 2017
• Constriction of the buccal branch of the facial nerve produces unilateral craniofacial allodynia 2017
• Aging with a traumatic brain injury: Could behavioral morbidities and endocrine symptoms be influenced by microglial priming? 2017
• Behavioral assessment of neuropathic pain, fatigue, and anxiety in experimental autoimmune encephalomyelitis (EAE) and attenuation by interleukin-10 gene therapy 2017
• Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury 2016
• The redox state of the alarmin HMGB1 is a pivotal factor in neuroinflammatory and microglial priming: A role for the NLRP3 inflammasome 2016
• The danger-associated molecular pattern HMGB1 mediates the neuroinflammatory effects of methamphetamine 2016
• Sleep fragmentation and sepsis differentially impact blood-brain barrier integrity and transport of tumor necrosis factor-α in aging 2015
• (+)-Naltrexone is neuroprotective and promotes alternative activation in the mouse hippocampus after cardiac arrest/cardiopulmonary resuscitation 2015
• Selective contributions of neuronal and astroglial interleukin-1 receptor 1 to the regulation of sleep 2015
• Stress sounds the alarmin: The role of the danger-associated molecular pattern HMGB1 in stress-induced neuroinflammatory priming 2015
• Influence of sleep deprivation and circadian misalignment on cortisol, inflammatory markers, and cytokine balance 2015
• Resolvins AT-D1 and E1 differentially impact functional outcome, post-traumatic sleep, and microglial activation following diffuse brain injury in the mouse 2015
• Sleep and immunity: A growing field with clinical impact 2015
• The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice 2015
• Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats 2015
• Alcohol-induced sedation and synergistic interactions between alcohol and morphine: A key mechanistic role for Toll-like receptors and MyD88-dependent signaling 2015
• Microglia inflammatory responses are controlled by an intrinsic circadian clock 2015
• Acute increases in intramuscular inflammatory cytokines are necessary for the development of mechanical hypersensitivity in a mouse model of musculoskeletal sensitization 2015
• Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain 2015
• The role of hepatic and splenic macrophages in E. coli-induced memory impairments in aged rats 2015
• High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor antagonism 2014
• Reduced sleep, stress responsivity, and female sex contribute to persistent inflammation-induced mechanical hypersensitivity in rats 2014
• Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acute stress in white adipose tissue of lean rats 2014
• Adrenergic and glucocorticoid modulation of the sterile inflammatory response 2014
• Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling 2013
• Stress-induced glucocorticoids as a neuroendocrine alarm signal of danger 2013
• 38. Evaluation of exosomal microRNA expression following exposure to acute stress 2013
• 65. Catecholamine and glucocorticoid modulation of stress-induced inflammatory cytokines and Hsp72 in subcutaneous adipose tissue 2013
• Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge 2013
• Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain 2013
• The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure 2013
• Stress-evoked sterile inflammation, danger associated molecular patterns (DAMPs), microbial associated molecular patterns (MAMPs) and the inflammasome 2013
• Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy 2012
• Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses 2012
• Stress and skin leukocyte trafficking as a dual-stage process 2012
• The impact of acute-stressor exposure on splenic innate immunity: A gene expression analysis 2012
• Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation 2011
• Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains 2011
• Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment 2011
• Stress- and glucocorticoid-induced priming of neuroinflammatory responses: Potential mechanisms of stress-induced vulnerability to drugs of abuse 2011
• Lymphocytes in neuroprotection, cognition and emotion: Is intolerance really the answer? 2011
• Sleep and fatigue in mice infected with murine gammaherpesvirus 68 2011
• The gut microbiota: A new player in the innate immune stress response? 2011
• Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats 2010
• Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain 2010
• IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344 x BN F1 rats 2010
• Evidence that opioids may have toll-like receptor 4 and MD-2 effects 2010
• Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide 2010
• Characterization of the sickness response in young and aging rats following E. coli infection 2009
• The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release 2009
• Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast) 2009
• Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy 2009
• Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection 2009
• Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia 2008
• Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia 2008
• Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge 2008
• Cardiovascular exercise intervention improves the primary antibody response to keyhole limpet hemocyanin (KLH) in previously sedentary older adults 2008
• Sleep-wake behavior and responses to sleep deprivation of mice lacking both interleukin-1β receptor 1 and tumor necrosis factor-α receptor 1 2008
• Early-life infection leads to altered BDNF and IL-1β mRNA expression in rat hippocampus following learning in adulthood 2008
• The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults 2007
• A novel immune-to-CNS communication pathway: Cells of the meninges surrounding the spinal cord CSF space produce proinflammatory cytokines in response to an inflammatory stimulus 2007
• Immune and glial regulation of pain 2007
• Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120 2007
• Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats 2007
• Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood 2007
• Glia as the "bad guys": Implications for improving clinical pain control and the clinical utility of opioids 2007
• Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses 2007
• Lipopolysaccharide has indomethacin-sensitive actions on Fos expression in topographically organized subpopulations of serotonergic neurons 2006
• Altitude training and immune function 2005
• Translational research using in vivo measures of primary antibody responses 2005
• Immune-to-brain communication dynamically modulates pain: Physiological and pathological consequences 2005
• Diurnal variation of lipopolysaccharide-induced alterations in sleep and body temperature of interleukin-6-deficient mice 2005
• Sleep-wake behavior and responses of interleukin-6-deficient mice to sleep deprivation 2005
• Cytokines and sleep: the first hundred years 2004
• Sleep, but not febrile responses of Fisher 344 rats to immune challenge are affected by aging 2004
• A method for measuring multiple cytokines from small samples 2004
• Immune-to-central nervous system communication and its role in modulating pain and cognition: Implications for cancer and cancer treatment 2003
• Prior stressor exposure sensitizes LPS-induced cytokine production 2002
• Selective effects of peripheral lipopolysaccharide administration on contextual and auditory-cue fear conditioning 1998
• STRESSED RATS FAIL TO EXPAND THE CD45RC(+)CD4(+) (TH1-LIKE) T-CELL SUBSET IN RESPONSE TO KLH - POSSIBLE INVOLVEMENT OF IFN-GAMMA 1995
• DIURNAL AND ACUTE STRESS-INDUCED CHANGES IN DISTRIBUTION OF PERIPHERAL-BLOOD LEUKOCYTE SUBPOPULATIONS 1994
• MORPHINE-INDUCED DECREASES IN IN-VIVO ANTIBODY-RESPONSES 1994
• Suppression of specific antibody production by inescapable shock: stability under varying conditions. 1988
• Effects of immunoregulatory Mycobacterium vaccae on consequences of early life adversity in combination with chronic psychosocial stress during adulthood 2022
• Glucocorticoids mediate stress-induced upregulation of the alarmin HMGB1 and downregulation of the inhibitory receptor CD200R1 in hippocampus and amygdala: A mechanism of neuroinflammatory priming 2019
• Gut microbial modulatory diets modulate stress-evoked sterile inflammation 2019
• Mycobacterium vaccae immunization protects aged rats from surgery-elicited neuroinflammation and cognitive dysfunction 2019
• Spinal cord injury perturbs circadian rhythms 2019
• The TLR2/4 antagonist (+)-naltrexone blocks contextual long-term memory deficits in experimental autoimmune encephalitis and associated neuroinflammation in hippocampus 2019
• Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis 2017

Research

keywords

• 1107 Immunology, 1109 Neurosciences, 1701 Psychology