Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats
Journal Article
Overview
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Animal Diseases - Disease Models, Animal
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Animals
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Antigens, Surface - CD11b Antigen
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Antineoplastic Agents, Phytogenic
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Biological Factors - Cytokines
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Biological Factors - Interleukin-10
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Biological Factors - Interleukin-1beta
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Biological Factors - Interleukin-1beta
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Biological Factors - Tumor Necrosis Factor-alpha
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Biological Factors - Tumor Necrosis Factor-alpha
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Biological Therapy - Genetic Therapy
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Blood Proteins - Tumor Necrosis Factor-alpha
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Cells - Neuroglia
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Cyclodecanes - Paclitaxel
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Diterpenes - Paclitaxel
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Ganglia - Ganglia, Spinal
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Genetic Engineering - Genetic Therapy
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Injections, Spinal
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Integrin alpha Chains - CD11b Antigen
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Male
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Membrane Proteins - CD11b Antigen
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Meninges
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Models, Animal - Disease Models, Animal
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Models, Biological - Disease Models, Animal
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Nervous System - Neuroglia
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Nervous System Diseases - Hyperalgesia
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Nervous System Physiological Phenomena - Pain Threshold
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Peptides - Cytokines
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Peptides - Interleukin-10
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Peptides - Interleukin-1beta
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Peptides - Interleukin-1beta
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Peptides - Tumor Necrosis Factor-alpha
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Peptides - Tumor Necrosis Factor-alpha
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Peripheral Nervous System - Ganglia, Spinal
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Peripheral Nervous System Diseases
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Plasmids
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Proteins - CD11b Antigen
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Proteins - Cytokines
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Proteins - Interleukin-10
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Proteins - Interleukin-1beta
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Proteins - Interleukin-1beta
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Proteins - Tumor Necrosis Factor-alpha
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Proteins - Tumor Necrosis Factor-alpha
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Proteins - Tumor Necrosis Factor-alpha
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Psychological Phenomena - Pain Threshold
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RNA, Messenger
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Rats
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Rats, Sprague-Dawley
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Receptors, Complement - CD11b Antigen
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Receptors, Interleukin-1
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Sensory Thresholds - Pain Threshold
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Signs and Symptoms - Hyperalgesia
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Spinal Cord
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Spinal Nerve Roots - Ganglia, Spinal
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Date in CU Experts
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September 6, 2013 4:09 AM
Full Author List
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Ledeboer A; Jekich BM; Sloane EM; Mahoney JH; Langer SJ; Milligan ED; Martin D; Maier SF; Johnson KW; Leinwand LA
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