Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy
Journal Article
Overview
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Animal Diseases - Disease Models, Animal
Animals
Animals, Inbred Strains - Rats, Inbred Strains
Autoantigens - Myelin-Oligodendrocyte Glycoprotein
Autoimmune Diseases - Encephalomyelitis, Autoimmune, Experimental
Autoimmune Diseases - Multiple Sclerosis
Behavior - Motor Activity
Biological Factors - Interleukin-10
Biological Science Disciplines - Immunohistochemistry
Biological Science Disciplines - Immunohistochemistry
Biological Therapy - Genetic Therapy
Chemistry - Immunohistochemistry
Chemistry - Immunohistochemistry
Cytoskeletal Proteins - Glial Fibrillary Acidic Protein
Demyelinating Diseases - Encephalomyelitis, Autoimmune, Experimental
Demyelinating Diseases - Multiple Sclerosis
Diagnostic Techniques and Procedures - Immunohistochemistry
Diagnostic Techniques and Procedures - Immunohistochemistry
Environment and Public Health - Analysis of Variance
Genetic Engineering - Genetic Therapy
Growth - Body Weight
Health Care Evaluation Mechanisms - Analysis of Variance
Hindlimb
Histology - Immunohistochemistry
Immunologic Techniques - Immunohistochemistry
Inflammation
Investigative Techniques - Analysis of Variance
Investigative Techniques - Body Weight
Investigative Techniques - Immunohistochemistry
Investigative Techniques - Immunohistochemistry
Leukoencephalopathies - Encephalomyelitis, Autoimmune, Experimental
Macromolecular Substances - Glial Fibrillary Acidic Protein
Male
Membrane Proteins - Myelin Proteins
Membrane Proteins - Myelin-Associated Glycoprotein
Membrane Proteins - Myelin-Associated Glycoprotein
Membrane Proteins - Myelin-Oligodendrocyte Glycoprotein
Membrane Proteins - Myelin-Oligodendrocyte Glycoprotein
Models, Animal - Disease Models, Animal
Models, Animal - Encephalomyelitis, Autoimmune, Experimental
Models, Biological - Disease Models, Animal
Musculoskeletal Physiological Phenomena - Motor Activity
Nerve Tissue Proteins - Myelin Proteins
Nerve Tissue Proteins - Myelin-Associated Glycoprotein
Nerve Tissue Proteins - Myelin-Oligodendrocyte Glycoprotein
Nervous System Diseases - Encephalomyelitis, Autoimmune, Experimental
Nervous System Diseases - Multiple Sclerosis
Nervous System Diseases - Paralysis
Peptides - Interleukin-10
Peripheral Nervous System Diseases - Neuralgia
Physical Examination - Body Weight
Physiological Phenomena - Body Weight
Proteins - Interleukin-10
Proteins - Myelin-Associated Glycoprotein
Proteins - Myelin-Oligodendrocyte Glycoprotein
Rats
Rats - Rats, Inbred Strains
Sialic Acid Binding Immunoglobulin-like Lectins - Myelin-Associated Glycoprotein
Signs and Symptoms - Body Weight
Signs and Symptoms - Neuralgia
Signs and Symptoms - Paralysis
Spinal Cord
Time Factors
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Sloane E; Ledeboer A; Seibert W; Coats B; van Strien M; Maier SF; Johnson KW; Chavez R; Watkins LR; Leinwand L
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