subject area of
- (+)-Naloxone, an Opioid-Inactive Toll-Like Receptor 4 Signaling Inhibitor, Reverses Multiple Models of Chronic Neuropathic Pain in Rats Journal Article
- A Peptide Antagonist of the TLR4-MD2 Interaction Journal Article
- A minocycline derivative reduces nerve injury-induced allodynia, LPS-induced prostaglandin E2 microglial production and signaling via toll-like receptors 2 and 4 Journal Article
- ACTIVATION OF ADULT RAT CNS ENDOTHELIAL CELLS BY OPIOID-INDUCED TOLL-LIKE RECEPTOR 4 (TLR4) SIGNALING INDUCES PROINFLAMMATORY, BIOCHEMICAL, MORPHOLOGICAL, AND BEHAVIORAL SEQUELAE Journal Article
- Alcohol-induced sedation and synergistic interactions between alcohol and morphine: A key mechanistic role for Toll-like receptors and MyD88-dependent signaling Journal Article
- An MD2 Hot-Spot-Mimicking Peptide that Suppresses TLR4-Mediated Inflammatory Response in vitro and in vivo Journal Article
- Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions Journal Article
- Bacterial Stimulation of Toll-Like Receptor 4 Drives Macrophages To Hemophagocytose Journal Article
- Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge Journal Article
- DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling Journal Article
- Discovery of a Novel Site of Opioid Action at the Innate Immune Pattern-Recognition Receptor TLR4 and its Role in Addiction Journal Article
- Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists Journal Article
- EVIDENCE FOR A ROLE OF HEAT SHOCK PROTEIN-90 IN TOLL LIKE RECEPTOR 4 MEDIATED PAIN ENHANCEMENT IN RATS Journal Article
- EVIDENCE THAT INTRATHECAL MORPHINE-3-GLUCURONIDE MAY CAUSE PAIN ENHANCEMENT VIA TOLL-LIKE RECEPTOR 4/MD-2 AND INTERLEUKIN-1β Journal Article
- EVIDENCE THAT TRICYCLIC SMALL MOLECULES MAY POSSESS TOLL-LIKE RECEPTOR AND MYELOID DIFFERENTIATION PROTEIN 2 ACTIVITY Journal Article
- Effect of Chronic. Delivery of the Toll-like Receptor 4 Antagonist (+)-Naltrexone on Incubation of Heroin Craving Journal Article
- Evidence that opioids may have toll-like receptor 4 and MD-2 effects Journal Article
- Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone Journal Article
- Glial TLR4 signaling does not contribute to opioid-induced depression of respiration Journal Article
- Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain Journal Article
- In vivo veritas: (+)-Naltrexone's actions define translational importance A letter in response to Skolnick et al. 'Translational potential of naloxone and naltrexone as TLR4 antagonists' Journal Article
- Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice Journal Article
- Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking Journal Article
- Interactions between TLR4 methylation and alcohol consumption on subjective responses to an alcohol infusion Journal Article
- Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain Journal Article
- Methamphetamine Activates Toll-Like Receptor 4 to Induce Central Immune Signaling within the Ventral Tegmental Area and Contributes to Extracellular Dopamine Increase in the Nucleus Accumbens Shell Journal Article
- Morphine activates neuroinflammation in a manner parallel to endotoxin Journal Article
- Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury Journal Article
- Mycobacterium vaccae protects against glucocorticoid resistance resulting from combined physical and psychosocial trauma in mice Journal Article
- Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: Comparison of different mouse strains Journal Article
- Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4) Journal Article
- Opioid Activation of Toll-Like Receptor 4 Contributes to Drug Reinforcement Journal Article
- Opioid-Induced Central Immune Signaling: Implications for Opioid Analgesia Journal Article
- POSSIBLE INVOLVEMENT OF TOLL-LIKE RECEPTOR 4/MYELOID DIFFERENTIATION FACTOR-2 ACTIVITY OF OPIOID INACTIVE ISOMERS CAUSES SPINAL PROINFLAMMATION AND RELATED BEHAVIORAL CONSEQUENCES Journal Article
- Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4 Journal Article
- Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats Journal Article
- Prior exposure to glucocorticoids sensitizes the neuroinflammatory and peripheral inflammatory responses to E. coli lipopolysaccharide Journal Article
- Protraction of neuropathic pain by morphine is mediated by spinal damage associated molecular patterns (DAMPs) in male rats Journal Article
- Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain Journal Article
- Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain Journal Article
- Sex and estradiol influence glial pro-inflammatory responses to lipopolysaccharide in rats Journal Article
- Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling Journal Article
- Stiffening-Induced High Pulsatility Flow Activates Endothelial Inflammation via a TLR2/NF-κB Pathway (Retracted Article) Journal Article
- Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists Journal Article
- Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists Journal Article
- TLR4 Methylation Moderates the Relationship Alcohol Use Severity and Gray Matter Loss Journal Article
- Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4 Journal Article
- The "Toll" of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia Journal Article
- The cortical innate immune response increases local neuronal excitability leading to seizures Journal Article
- Toll -like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain Journal Article
- Toll-like receptor 4 antagonists reduce cocaine-primed reinstatement of drug seeking Journal Article
- Toll-like receptor 4 in CNS pathologies Journal Article