Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists
Journal Article
Overview
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Animals
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Antigens, Bacterial - Lipopolysaccharides
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Biochemical Phenomena - Structure-Activity Relationship
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Cell Line
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Cells - Microglia
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Central Nervous System Agents - Analgesics, Opioid
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Central Nervous System Agents - Analgesics, Opioid
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Drug Synergism
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Endotoxins - Lipopolysaccharides
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Glycoconjugates - Lipopolysaccharides
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Heterocyclic Compounds, 4 or More Rings - Morphinans
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Heterocyclic Compounds, 4 or More Rings - Morphine
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Heterocyclic Compounds, 4 or More Rings - Naltrexone
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Heterocyclic Compounds, Bridged-Ring - Morphinans
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Heterocyclic Compounds, Bridged-Ring - Morphine
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Heterocyclic Compounds, Bridged-Ring - Naltrexone
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Humans
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Inorganic Chemicals - Nitric Oxide
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Lipids - Lipopolysaccharides
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Male
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Nervous System - Microglia
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Nitrogen Compounds - Nitric Oxide
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Nitrogen Compounds - Nitric Oxide
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Opiate Alkaloids - Morphinans
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Opiate Alkaloids - Morphine
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Opiate Alkaloids - Naltrexone
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Oxygen Compounds - Nitric Oxide
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Pharmacological Phenomena - Structure-Activity Relationship
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Physiological Effects of Drugs - Analgesics, Opioid
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Polycyclic Compounds - Morphinans
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Polycyclic Compounds - Morphine
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Polycyclic Compounds - Naltrexone
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Polysaccharides - Lipopolysaccharides
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Rats
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Rats, Sprague-Dawley
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Sensory System Agents - Analgesics, Opioid
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Toll-Like Receptor 4
Date in CU Experts
Full Author List
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Selfridge BR; Wang X; Zhang Y; Yin H; Grace PM; Watkins LR; Jacobson AE; Rice KC
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