Dr. Bryant's research focuses on designing 3D biomaterials, which she employs 3D models to answer fundamental biological questions and designs 3D cell scaffolds to guide tissue growth and integration for regenerative medicine. In particular, her laboratory has a keen interest in understanding mechanotransduction pathways in cells and understanding the importance of loading in tissue regeneration for cartilage, bone, tendon, and cardiovascular tissues. Her laboratory has also been very interested in uncovering the mechanisms of how the body responds to implanted biomaterials and using this knowledge to develop novel strategies that promote healing and facilitate integration of the engineered tissue into the host tissue, supporting long-term function. Through careful control over the 3D environment, particularly in the presence of physiological cues, her lab hopes to better understand cellular processes towards translating her materials-based technologies in vivo and improving functional tissue regeneration and integration.
tissue engineering and regenerative medicine, biomaterials, mechanotransduction, immunology
CHEN 3210 - Chemical Engineering Heat Transfer
Examines conservation and transfer of mass and thermal energy. Focuses on conduction and convection of heat in the context of chemical processes and heat exchangers. Addresses radiation. Also studies mass transfer rate processes, including diffusion, microscopic material balances, and correlations for mass transfer coefficients.
CHEN 5160 - Systems Analysis of Cells and Tissues
Required for the Biological Engineering PhD. This course explores how to describe signaling and regulation networks present at the cell and tissue level. Topics include gene expression, stem cell differentiation, homeostasis, and others. Recommended prerequisite: prior experience in introductory biology and/or biochemistry, linear algebra, differential equations, thermodynamics, and organic chemistry.
CHEN 5805 - Biological Interactions to Biomaterials
Fall 2020 / Spring 2021
Covers major classes of materials used in medical applications. Provide an in-depth view of advanced biomaterial concepts with a focus on biological interactions with materials that relate to protein and cell interactions, the innate and acquired immune response, blood interactions and infection.