Our lab is studying how proteins generate the shape of the endoplasmic reticulum (ER). We are using cell biology, biochemistry, and electron microscopy to study how membrane proteins and their partners determine the elaborate structure of the ER in yeast and mammalian cells.
keywords
membrane biology, organelle structure and morphology, membrane proteins
MCDB 3145 - Cell Biology
Primary Instructor
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Spring 2018 / Spring 2019 / Spring 2020 / Spring 2021 / Fall 2024
Examines intracellular mechanisms, including transport of ions and small molecules across membranes; protein targeting to organelles; membrane trafficking between organelles; signal transduction; the cytoskeleton; and the cell cycle. Recommended prerequisite or corequisite: MCDB 3140 concurrent with either this class or MCDB 3135.
MCDB 4425 - Topics in Membrane Biology: Cell Biology, Physiology and Disease
Primary Instructor
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Spring 2023
Students will apply their knowledge of basic biology to exploring several of the most exciting topics in biomedicine including protein folding and stress responses, nutrient sensing and balance and signal transduction across membranes. Emphasis will be placed upon human physiology and associated human diseases including Alzheimer's disease, diabetes and cardiovascular disease. Fulfills MCDB scientific reasoning requirement. Recommended prerequisites: MCDB 3135 and MCDB 3145 or instructor consent. Same as MCDB 5425.
MCDB 4980 - Honors Research
Primary Instructor
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Fall 2019 / Spring 2024
Provides faculty-supervised research for students who have been approved by the departmental honors committee. Normally taken during the semester before completion of the honors thesis. Recommended prerequisite: MCDB 4840 or comparable research experience, and minimum GPA of 3.20.
MCDB 4990 - Honors Thesis
Primary Instructor
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Spring 2019 / Spring 2020 / Spring 2022 / Spring 2023
Involves the preparation and defense of an honors thesis, based on faculty-supervised original research, including final phases of the research project. Recommended prerequisites: MCDB 4840 or MCDB 4980 or comparable research experience, and minimum GPA of 3.3 and approval by the MCDB Honors Committee.
MCDB 5425 - Topics in Membrane Biology: Cell Biology, Physiology and Disease
Primary Instructor
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Spring 2023
Students will apply their knowledge of basic biology to exploring several of the most exciting topics in biomedicine including protein folding and stress responses, nutrient sensing and balance and signal transduction across membranes. Emphasis will be placed upon human physiology and associated human diseases including Alzheimer's disease, diabetes and cardiovascular disease. Same as MCDB 4425.
MCDB 6000 - Introduction to Laboratory Methods
Primary Instructor
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Spring 2019 / Spring 2020 / Spring 2021 / Fall 2022 / Fall 2023 / Spring 2024 / Fall 2024
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.
MCDB 6441 - Faculty Res Seminar
Primary Instructor
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Fall 2022 / Fall 2023 / Fall 2024
Acquaints students with various topics not normally covered in the curriculum. Offered intermittently or upon student demand, and often presented by visiting professors.
MCDB 7910 - Seminar Practicum
Primary Instructor
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Spring 2018 / Fall 2022 / Spring 2023 / Fall 2023 / Spring 2024 / Fall 2024
Designed for graduate students to give oral presentations on their thesis research, field questions, respond to critiques, and present background information. Students attend weekly seminar speaker presentations to gain knowledge on specialized research. May be repeated up to 4 total credit hours.
