Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors
Journal Article
Overview
publication date
- March 15, 2008
has subject area
- Animals
- Azoles - Oxythiamine
- Azoles - Thiamine
- Biochemical Phenomena - Molecular Structure
- Biochemical Phenomena - Phosphorylation
- Biochemical Phenomena - Structure-Activity Relationship
- Chemical Phenomena - Molecular Structure
- Colonic Diseases - Colonic Neoplasms
- Crystallography, X-Ray
- Digestive System Diseases - Colonic Neoplasms
- Enzyme Inhibitors
- Enzymes - Ketoglutarate Dehydrogenase Complex
- Gastrointestinal Diseases - Colonic Neoplasms
- Glucosephosphate Dehydrogenase
- Humans
- In Vitro Techniques
- Intestinal Diseases - Colonic Neoplasms
- Investigative Techniques - Xenograft Model Antitumor Assays
- Ketone Oxidoreductases - Ketoglutarate Dehydrogenase Complex
- Lymphatic System - Spleen
- Magnetic Resonance Spectroscopy
- Metabolism - Phosphorylation
- Mice
- Mice, Nude
- Multiprotein Complexes - Ketoglutarate Dehydrogenase Complex
- Neoplasm Transplantation - Xenograft Model Antitumor Assays
- Neoplasms by Site - Colonic Neoplasms
- Organic Chemicals - Oxythiamine
- Organic Chemicals - Thiamine
- Organic Chemistry Phenomena - Phosphorylation
- Pharmacological Phenomena - Structure-Activity Relationship
- Pyrimidines - Thiamine
- Tissues - Spleen
- Transketolase
has restriction
- closed
Date in CU Experts
- September 3, 2013 10:07 AM
Full Author List
- Thomas AA; Le Huerou Y; De Meese J; Gunawardana I; Kaplan T; Romoff TT; Gonzales SS; Condroski K; Boyd SA; Ballard J
author count
- 25
citation count
- 42
published in
Other Profiles
International Standard Serial Number (ISSN)
- 0960-894X
Digital Object Identifier (DOI)
Additional Document Info
start page
- 2206
end page
- 2210
volume
- 18
issue
- 6