Conformational properties of oligonucleotides. Journal Article uri icon



  • Vast libraries of oligonucleotide sequences can be made. Such libraries have been screened and/or selected to identify individual molecules showing various properties, including high affinity/high specificity binding (to something) or new enzymatic activity. The SELEX protocol is used to identify these interesting oligonucleotides; two recent reviews of the SELEX protocol and its power have appeared recently. Oligonucleotides derived through the SELEX process have applications in diagnostics and therapeutics, and have additional value as research reagents and compounds that provide chemical plausibility to some ideas about evolution of the biosphere. Oligonucleotide conformations are shockingly robust and potent.

publication date

  • January 1, 1995

Date in CU Experts

  • September 9, 2013 9:29 AM

Full Author List

  • Gold L

author count

  • 1

Other Profiles

International Standard Serial Number (ISSN)

  • 0261-3166

Additional Document Info

start page

  • 20

end page

  • 22


  • 33