Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation
Journal Article
Overview
publication date
- June 14, 2016
has subject area
- Animals
- Animals, Inbred Strains - Rats, Inbred F344
- Biological Factors - Interleukin-1beta
- Biological Factors - Interleukin-1beta
- Cells - Microglia
- Chronic Pain
- Clozapine
- Heterocyclic Compounds, 4 or More Rings - Morphine
- Heterocyclic Compounds, Bridged-Ring - Morphine
- Inflammasomes
- Male
- NLR Family, Pyrin Domain-Containing 3 Protein
- Nervous System - Microglia
- Opiate Alkaloids - Morphine
- Peptides - Interleukin-1beta
- Peptides - Interleukin-1beta
- Peripheral Nervous System Diseases - Neuralgia
- Polycyclic Compounds - Morphine
- Proteins - Interleukin-1beta
- Proteins - Interleukin-1beta
- Rats
- Rats - Rats, Inbred F344
- Rats, Sprague-Dawley
- Signs and Symptoms - Neuralgia
- Spinal Cord Dorsal Horn
has restriction
- green
Date in CU Experts
- June 3, 2016 4:08 AM
Full Author List
- Grace PM; Strand KA; Galer EL; Urban DJ; Wang X; Baratta MV; Fabisiak TJ; Anderson ND; Cheng K; Greene LI
author count
- 19
citation count
- 255
published in
Other Profiles
International Standard Serial Number (ISSN)
- 0027-8424
Digital Object Identifier (DOI)
Additional Document Info
start page
- E3441
end page
- E3450
volume
- 113
issue
- 24