A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
Journal Article
Overview
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Adenosine Triphosphatases
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Adenosine Triphosphatases - Cardiac Myosins
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Adenosine Triphosphatases - Myosin Heavy Chains
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Amines - Benzylamines
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Animal Diseases - Disease Models, Animal
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Animals
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Animals, Inbred Strains - Mice, Inbred Strains
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Aortic Valve Disease - Cardiomyopathy, Hypertrophic, Familial
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Benzyl Compounds - Benzylamines
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Cardiomyopathies - Cardiomyopathy, Hypertrophic, Familial
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Cardiovascular Physiological Phenomena - Myocardial Contraction
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Cells, Cultured
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Cytoskeletal Proteins - Cardiac Myosins
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Cytoskeletal Proteins - Myosin Heavy Chains
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Fibrosis
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Genetic Diseases, Inborn - Cardiomyopathy, Hypertrophic, Familial
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Heart - Myocardium
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Heart - Myocytes, Cardiac
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Heart Ventricles
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Heterozygote
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Humans
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Macromolecular Substances - Cardiac Myosins
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Macromolecular Substances - Myosin Heavy Chains
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Male
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Mice
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Mice - Mice, Inbred Strains
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Models, Animal - Disease Models, Animal
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Models, Biological - Disease Models, Animal
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Muscle Cells - Myocytes, Cardiac
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Muscle Cells - Sarcomeres
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Muscle Cells - Sarcomeres
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Muscle Contraction - Myocardial Contraction
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Muscle Proteins - Cardiac Myosins
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Muscle Proteins - Myosin Heavy Chains
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Muscle, Striated - Myocardium
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Muscle, Striated - Myocytes, Cardiac
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Muscle, Striated - Sarcomeres
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Musculoskeletal System - Myocardium
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Mutation
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Organelles - Sarcomeres
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Rats
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Uracil
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Date in CU Experts
Full Author List
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Green EM; Wakimoto H; Anderson RL; Evanchik MJ; Gorham JM; Harrison BC; Henze M; Kawas R; Oslob JD; Rodriguez HM
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