Biophysical Journal Journal

Overview

publication venue for

• Ras signaling mechanisms: New insights from single-molecule biophysics. 2024
• Coiled-coil domains are sufficient to drive liquid-liquid phase separation in protein models 2024
• Similarly slow diffusion of BAM and SecYEG complexes in live E. coli cells observed with 3D spt-PALM 2023
• PDK1:PKCa heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane 2023
• Mechanical memory stored through epigenetic remodeling reduces cell therapeutic potential 2023
• Multiscale mechanobiology: Coupling models of adhesion kinetics and nonlinear tissue mechanics 2022
• Motor guidance by long-range communication through the microtubule highway 2022
• Dedifferentiation alters chondrocyte nuclear mechanics during in vitro culture and expansion 2022
• Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC 2021
• Image-derived modeling of nucleus strain amplification associated with chromatin heterogeneity 2021
• C-Terminal Tail Polyglycylation and Polyglutamylation Alter Microtubule Mechanical Properties 2020
• The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism 2020
• TENSCell: Imaging of Stretch-Activated Cells Reveals Divergent Nuclear Behavior and Tension 2020
• Membrane-Protein Unfolding Intermediates Detected with Enhanced Precision Using a Zigzag Force Ramp 2020
• Bound-State Diffusion due to Binding to Flexible Polymers in a Selective Biofilter 2020
• Q-FADD: A Mechanistic Approach for Modeling the Accumulation of Proteins at Sites of DNA Damage 2019
• Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly 2019
• A Statistical Model of Expansive Growth in Plant and Fungal Cells: The Case of Phycomyces. 2018
• In-Cell NMR within Budding Yeast Reveals Cytoplasmic Masking of Hydrophobic Residues of FG Repeats 2018
• FEATHER: Automated Analysis of Force Spectroscopy Unbinding and Unfolding Data via a Bayesian Algorithm 2018
• A Multicolor Split-Fluorescent Protein Approach to Visualize Listeria Protein Secretion in Infection 2018
• Single-Molecule Resolution of Antimicrobial Peptide Interactions with Supported Lipid A Bilayers 2018
• Calsequestrin-Mediated Mechanism for Cellular Calcium Transient Alternans (vol 95, pg 3767, 2008) 2018
• Force Spectroscopy with 9-μs Resolution and Sub-pN Stability by Tailoring AFM Cantilever Geometry 2017
• Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP₃ Signaling 2017
• Temperature-Induced Transitions in the Structure and Interfacial Rheology of Human Meibum (vol 102, pg 369, 2012) 2017
• Caveolae in Rabbit Ventricular Myocytes: Distribution and Dynamic Diminution after Cell Isolation 2017
• Response to Comment to the Editor 2017
• Contributions of Microtubule Dynamic Instability and Rotational Diffusion to Kinetochore Capture 2017
• Cadherin Diffusion in Supported Lipid Bilayers Exhibits Calcium-Dependent Dynamic Heterogeneity 2016
• Challenges in Predicting Protein-Protein Interactions from Measurements of Molecular Diffusivity 2016
• BamA POTRA Domain Interacts with a Native Lipid Membrane Surface 2016
• Motor Protein Accumulation on Antiparallel Microtubule Overlaps 2016
• Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway 2016
• Single-Molecule FRET Reveals Three Conformations for the TLS Domain of Brome Mosaic Virus Genome 2015
• DNA Motion Capture Reveals the Mechanical Properties of DNA at the Mesoscale 2015
• Cytoplasmic Freezing in S. Pombe upon Glucose Starvation 2015
• Disulfide Trapping and Spectroscopic Studies of Bacterial Chemosensory Core Signaling Complexes: Probing Molecular Mechanisms of Complex Assembly and Receptor-Regulated On-Off Switching 2015
• Functional Analysis of Freeman-Sheldon Syndrome Causing Mutations on Embryonic Myosin 2015
• Molecular Mechanisms that Regulate the Coupled Period of the Mammalian Circadian Clock 2014
• Dimensionality and Size Scaling of Coordinated Ca2+ Dynamics in MIN6 beta-cell Clusters 2014
• Pulsed IR Heating Studies of Single-Molecule DNA Duplex Dissociation Kinetics and Thermodynamics 2014
• Dimensionality and Calcium Dynamics in Pancreatic beta-Cell Clusters 2013
• Probing the Structural Origins of Unusually Strong Target Membrane Affinity of Synaptotagmin 7 C2A and C2Ab Domains 2013
• Structural and Biochemical Characterization of a New Zincin Protease, NleC, an Enteropathogenic Escherichia Coli Type III Secretion System Effector Responsible for Cleaving NF kappa B Subunit Rela 2013
• Apparent Activation Energies Associated with Protein Dynamics on Hydrophobic and Hydrophilic Surfaces 2012
• Mapping Three-Dimensional Stress and Strain Fields within a Soft Hydrogel Using a Fluorescence Microscope 2012
• Temperature-induced transitions in the structure and interfacial rheology of human meibum (vol 102, pg 369, 2012) 2012
• Analysis of Protein Complex Formation on Membrane Surfaces by Single Molecule Diffusion 2012
• Heterogeneity and Kinetics of FRET-Based Ca2+ and Zn2+ Sensors in HeLa Cells 2012
• Microfluidic Cytometer For Simultaneous High-Throughput Screening of Fluorescent Proteins on the Basis of Fluorescence Lifetime, Photostability, and Brightness 2012
• Synaptotagmin C2 Domain Membrane Targeting: Kinetic and Mechanistic Diversity Among Isoforms from Different Cell Types 2012
• Target Specific Phosphorylation of Cardiac Troponin I and Sex Dimorphic Myofilament Function in R403Q Mice 2012
• Temperature-Induced Transitions in the Structure and Interfacial Rheology of Human Meibum 2012
• Analysis of Red-Fluorescent Proteins Provides Insight into Dark-State Conversion and Photodegradation 2011
• Effects of Gel Thickness on Microscopic Indentation Measurements of Gel Modulus 2011
• A Microfluidic Cell Sorter for Directed Evolution of Fluorescent Proteins Based on Dark-State Conversion and Photobleaching 2011
• Kinetic Analysis of Human alpha and beta Cardiac Myosin Motor Domains 2011
• Protein-Lipid Interactions Shaping the Electrostatic Membrane Search of a Pleckstrin Homology Domain 2011
• Surface Creasing Instability of Soft Polyacrylamide Cell Culture Substrates 2010
• Single Molecule Diffusion of Membrane-Bound Proteins: Window into Lipid Contacts and Bilayer Dynamics 2010
• A Microfluidic Cytometer for High-Throughput and Quantitative Single Cell Red Fluorescent Protein Photobleaching 2010
• Cell Elastic Modulus Cytometry using Diode-Bar Optical Stretchers 2010
• Membrane Diffusion of PH Domain-PIP3 Complexes: the Effects of Target Lipid Stoichiometry on Diffusion Constant Probed Using Single-Molecule Fluorescence Microscopy 2010
• Second Messengers at the Leading Edge: Calcium Joins PIP3 as an Essential Signal 2010
• Structural Analysis of the Membrane Docking Geometry of PI(3,4,5)P3-Specific GRP1-PH Domain Via Site-Directed Spin Labeling 2010
• Structural Insights into Metabolite-Sensing Messenger RNAs 2010
• Microtubule Depolymerization by the Kinesin-8 Motor Kip3p: A Mathematical Model 2009
• Precision Surface-Coupled Optical-Trapping Assay with One-Basepair Resolution 2009
• Single-Molecule Fluorescence Studies of a PH Domain: New Insights into the Membrane Docking Reaction 2009
• Calsequestrin-mediated mechanism for cellular calcium transient alternans 2008
• A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates 2008
• Role of GAP-43 in sequestering phosphatidylinositol 4,5-bisphosphate to raft bilayers 2008
• Elasticity of short DNA molecules:: Theory and experiment for contour lengths of 0.6-7 μm 2007
• Investigation of PH domain-membrane interactions using T1RFM 2007
• Self-induced docking site of a deeply embedded peripheral membrane protein 2007
• Structural and functional studies of the membrane targeting mechanism of phosphoinositide-specifie pleckstrin homology domains 2007
• Structure and mechanism of ligand recognition by the SAM and purine riboswitches 2007
• Combining experimental and computational techniques to reveal bases for ionic selectivity and binding in the cPLA(2) C2 domain 2005
• Molecular dynamics simulation of the C2 domain of cytosolic phospholipase A2 2005
• Forward and reverse motion of single RecBCD molecules on DNA 2004
• Altered thin filament cooperativity and cross-bridge kinetics due to expression of truncated cardiac troponin T 2004
• An early step in human mRNA transcription requires negative superhelicity on template DNA 2004
• Phosphorylation-dependent changes in structure and dynamics in ERK2 detected by SDSL and EPR 2004
• Structural dynamics of an RNA tertiary contact explored by single molecule fluorescence spectroscopy 2004
• Aspartate receptor transmembrane signaling and kinase regulation 2003
• Changes in cardiac thin filament regulation due to expression of truncated troponin T 2003
• Helicase opening of duplex nucleic acids: active versus passive opening 2003
• The impact of voluntary resistance training on murine skeletal and cardiac hypertrophy 2003
• Towards a further understanding of the poliovirus replication complex: The solution structure of poliovirus 3A protein 2003
• C2 domain of cPLA(2): Structural and dynamic analysis of Ca2+ activation and membrane docking 2002
• C2 domain of cPLA2: Structural analysis of Ca2+ activation and membrane docking 2002
• Functional proteomics analysis of PKC calcium-activated C2 domains 2002
• C2 domains of PKCa and PKCb: Functional differences 2001
• Conformations of the membrane-docking loops in a membrane-bound C2 domain. 2001
• Determining global conformation of nucleic acids in solution. 2001
• Probing the mechanisms of kinase regulation and covalent adaptation in the cytoplasmic domain of the aspartate receptor 2001
• The aspartate receptor: Mechanisms of covalent adaptation and kinase regulation 2001
• A mathematical model of cardiocyte Ca2+ dynamics with a novel representation of sarcoplasmic reticular Ca2+ control 2000
• Ca2+-activated membrane docking by the ubiquitous C2 domain: Comparison of C2 domains from different functional families. 2000
• ARG92GLN mutation in cTnT linked to familial hypertrophic cardiomyopathy causes increased Ca2+ sensitivity in mouse cardiac myofilaments. 1999
• C-terminal truncation of cTnT linked to familial hypertrophic cardiomyopathy alters Ca2+-regulation of mouse cardiac myofilament activation. 1999
• Calcium-activated membrane targetting by the C2 domain. 1999
• Comparison of cardiac and skeletal troponin C 1999
• Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2. 1999
• Myocytes isolated from mice expressing a truncated troponin T FHC mutation do not show altered Ca2+ activated force 1999
• The examination of cardiac cellular Ca2+ processes by mathematical modeling. 1999
• Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy 1998
• Characterization of truncated forms of human tissue factor-surfactant mixed micelles by analytical ultracentrifugation and EPR spectroscopy. 1997
• Kinetic characterization of myosin mutations that cause familial hypertrophic cardiomyopathy. 1997
• Patterned adsorption of in vitro centrosomes. 1997
• A general technique for patterning of functional proteins with photolithography of silane monolayers 1996
• Expression and characterization of rat cardiac alpha and beta myosin subfragment-1 in mammalian cells. 1996
• Tuning ion affinity and selectivity of the EF-hand Ca2+ binding motif: Changes at the gateway position 1996
• Localization of the retinal protonated Schiff base counterion in rhodopsin. 1993
• SOLUTION STRUCTURES OF RNA - RNA FOLDING MOTIFS AND RIBOZYMES 1993
• F-19 NUCLEAR-MAGNETIC-RESONANCE STUDIES OF AQUEOUS AND TRANSMEMBRANE RECEPTORS - EXAMPLES FROM THE ESCHERICHIA-COLI CHEMOSENSORY PATHWAY 1992
• STRUCTURE AND DYNAMICS OF ESCHERICHIA-COLI CHEMOSENSORY RECEPTORS - ENGINEERED SULFHYDRYL STUDIES 1992
• ENHANCED INTERNAL ELECTRON-TRANSFER WITHIN THE SUBUNIT 5B ISOZYME OF YEAST CYTOCHROME-OXIDASE 1990
• REGULATION OF SCALLOP MYOSIN BY MUTANT LIGHT-CHAINS 1990
• TRANSITION DIPOLE ORIENTATIONS IN THE EARLY PHOTOLYSIS INTERMEDIATES OF RHODOPSIN 1989
• PHOTOLYSIS INTERMEDIATES OF THE ARTIFICIAL VISUAL PIGMENT CIS-5,6-DIHYDRO-ISORHODOPSIN 1989
• THE NATURE OF THE PRIMARY PHOTOCHEMICAL EVENTS IN RHODOPSIN AND ISORHODOPSIN 1988
• EDGE STRUCTURES OF GENETICALLY ALTERED CYTOCHROME OXIDASES 1988
• SUBUNIT CONTROL OF CYTOCHROME-OXIDASE STRUCTURE AND ACTIVITY 1988
• CLONING AND CHARACTERIZATION OF THE ESSENTIAL AND REGULATORY LIGHT CHAIN CDNA IN SCALLOP STRIATED-MUSCLE 1987
• Ion Channels within Ion Transport Proteins 1984
• AUTO-REGULATION OF GENE-EXPRESSION - THE T4-CODED GENE-32 PROTEIN SYSTEM 1982
• HIGH-RESOLUTION X-RAY-DIFFRACTION OF PHOTORECEPTOR MULTILAYERS 1982
• STRUCTURE AND FUNCTION OF AN ACETYLCHOLINE-RECEPTOR 1982
• X-RAY-DIFFRACTION AND ELECTRON-MICROSCOPE STUDY OF PHASE-SEPARATION IN ROD OUTER SEGMENT PHOTORECEPTOR MEMBRANE MULTILAYERS 1982
• CHIRALLY ASYMMETRIC REVERSIBLE PHOTO BLEACHING IN PURPLE MEMBRANE FILMS 1981
• A SPECTROSCOPIC STUDY OF RHODOPSIN ALPHA-HELIX ORIENTATION 1980
• INCORPORATION OF PHOTORECEPTOR MEMBRANE INTO A MULTILAMELLAR FILM 1980
• SURFACE-INDUCED LAMELLAR ORIENTATION OF MULTILAYER MEMBRANE ARRAYS - THEORETICAL-ANALYSIS AND A NEW METHOD WITH APPLICATION TO PURPLE MEMBRANE-FRAGMENTS 1980
• POLARIZED INFRARED SPECTROSCOPY OF ORIENTED PURPLE MEMBRANE 1979
• INFRARED DICHROISM OF ORIENTED PURPLE MEMBRANE 1978
• FLUORESCENCE DEPOLARIZATION STUDIES OF CHLOROPHYLL IN ORIENTED LIPID MULTILAYERS 1976
• Analysis of Chemotaxis in White Blood Cells 1971
• A Theory of Necrotaxis 1970
• Action at a distance along the microtubule couples kinesin motors 2023
• Allosteric inhibition via nonpolar terpenoid inhibitors 2023
• Coiled-coil domains can drive liquid-liquid phase separation 2023
• Development and benchmarking of an open, self-consistent force field for proteins and small molecules from the open force field initiative 2023
• Fast, conformation-independent charges with graph convolutional networks 2023
• Building an open, self-consistent force field for biopolymers and small molecules with the open force field initiative infrastructure 2022
• Chromatin remodeling controls activation and persistence of aortic valve fibroblasts 2022
• Diverse structural mechanisms of muscle-type nicotinic receptor antagonism 2022
• Human CST assembles into a decameric supercomplex upon binding to single-stranded telomeric DNA 2022
• Nucleosome chaperones facilitate both nucleosome assembly and disassembly 2022
• Using NMR to probe the dynamics and properties of the C-terminal tubulin tails 2022
• Acidic Solutions to Archaeal Chromatin 2021
• Extracting Protein Recruitment Kinetics to DNA Damage using qFADD.py 2021
• Long-Range Coupling between Kinesins Regulates Collective Motor Behavior 2021
• PDK1 Forms Homodimers on Supported Lipid Bilayers in a PIP3 Dependent Manner 2021
• Rapid Search and Repair Strategies of DNA Damage Repair Proteins on Chromatin 2021
• Binding of Ras to PI3K: Measuring Binding Affinity, and the Effects of Disease-Linked H-Ras Mutations on Affinity 2020
• Biochemical and Structural Characterization of Enzymes Responsible of Polymyxin Resistance in Gram-Negative Bacteria 2020
• C-Terminal Tail Polyglycylation and Polyglutamylation Alter Microtubule Mechanical Properties 2020
• Cadherin Extracellular Domain Clustering in the Absence of Trans-Interactions 2020
• Development and Implementation of a Single-Molecule Platform to Study the Mechanism of the Beta-Barrel Assembly Machine Complex 2020
• Direct Detection and Characterization of a Phosphoinositide Dependent Kinase-1 (PDK1) Homodimer on a Target Membrane Surface Via Single Molecule Fluorescence 2020
• Elucidating Archaeal Chromatin ``Slinky'' Dynamics through Simulation and Experiment 2020
• Functional Comparison of Homologous Mutations in Human Beta, Perinatal, and Embryonic Muscle Myosin Isoforms 2020
• Functional Differences in MYH7b That Contribute to Distinct Biological Roles across Species and in Health and Disease 2020
• Investigation of Mechanically Labile Type III Secretion Protein Effectors 2020
• Pieces of the Puzzle: Individual hFACT Subdomains Coordinate to Remodel Nucleosomes 2020
• Post-Prandial Inotropic Response in Python Cardiomyocytes is Supported by Distinct Metabolic Adaptation 2020
• Regulatory Mechanisms of Ca2+, Receptor, Ras, and Lipid Signals that Control Actin Polymerization During Cell Migration 2020
• cryo-EM Structure of Rice OSCA1.2 Elucidates the Mechanical Basis of Membrane Hyperosmolality Gating in Plants 2020
• Characterization of Predicted Small Proteins 2019
• Destabilizing Nucleosomes and the Role of HMGB Proteins 2019
• Developing a Single-Molecule Platform to Understand Outer Membrane Protein Biogenesis 2019
• Mechanisms of Bidirectional Transport of Misaligned Chromosomes in Mitosis 2019
• Novel Morphological and Functional Insights in Python Cardiac Biology 2019
• Solution Dynamics in Histone-Based Archaeal Chromatin 2019
• A Multi-color Riboswitch-Based Platform for Imaging of MRNA and Small Non-coding RNA in Live Mammalian Cells 2018
• High Precision AFM-Based SMFS of Mechanically Labile T3SS Effectors 2018
• Mechanisms of Selective Transport through the Nuclear Pore Complex 2018
• Minimal Ingredients for Coupled Spindle Assembly and Chromosome Bi-orientation in a Computational Model of Fission Yeast Mitosis 2018
• Organization and Dynamics of Gliding Flexible Filaments Jeffrey M. Moore 2018
• Synthetic Mimics of the Nuclear Pore Complex 2018
• Complex Folding Pathways of Bacteriorhodopsin Revealed by 1-mu s-Resolution Force Spectroscopy 2016
• Dark State Dynamics of Red Fluorescent Proteins in the Cell Environment Measured in Microfluidic Flow 2016
• Effects of Obstacle Binding and Bound Mobility in a Lattice Model of Protein Diffusion 2016
• Effects of Obstacle Binding and Bound Mobility in a Lattice Model of Protein Diffusion 2016
• Enhanced Site-Specific Anchoring of Biomolecules for Single-Molecule Force Spectroscopy 2016
• Equilibrium Folding of an Individual Bacteriorhodopsin into and out of its Native Lipid Bilayer Resolves Energy Landscapes and Hidden Dynamics 2016
• Molecular Dissection of the Tubulin C-Terminal Tails by NMR 2016
• Multi-Parametric Microfluidic Screening and Sorting for Simultaneous Evolution of Photophysical Parameters of Fluorescent Proteins 2016
• Probing Single Individual Proteins Unfold and Refold with 1-mu s Resolution: Improved AFM-Based Single Molecule Force Spectroscopy 2016
• The Effect of Pediatric Specific Hypertrophic Cardiomyopathy Mutations on the Biomechanics of Beta Cardiac Myosin 2016
• The Role of Intrinsic Disorder in the Molecular Mechanism of Nuclear Transport 2016
• beta-MYHC Mutations Linked to Early-Onset HCM and DCM Show Differences in Pre-Steady and Steady State Kinetic Parameters 2016
• Photobleaching and Stability of Red Fluorescent Proteins 2015
• Motion and Conformational Entropy in Protein Function: Creation of an NMR-Based Entropy Meter 2015
• Structure and Function of the beta-Barrel Assembly Machine and its Associated Chaperones 2015
• Activation of PI3K by Ras: Single Molecule Studies of the Activation Mechanism 2014
• An Ultrastable Measurement Platform for Single-Molecule Studies: Sub-NM Lateral Stability Over 1 hour using a Multiplexed Back-Scattered Detection 2014
• Critical Evaluation of FRET-Based Biosensor Performance: Implications for Measuring Ion Concentrations 2014
• Extent of Nucleosome Destabilization Governs Yeast HMGB Cellular Function 2014
• Heterobifunctional Polyprotein for Efficient Characterization of Mechanically Labile Proteins 2014
• Improved Single-Molecule Force Spectroscopy Using Micro-Machined Cantilevers 2014
• In vitro Reconstitution to Understand the Mechanism of Bam 2014
• Modeling the Microscopic to Macroscopic Dynamics of Actively Streaming Microtubule Suspensions 2014
• Physical Determinants of Bipolar Mitotic Spindle Assembly and Stability in Fission Yeast 2014
• Protein Resilience and Fluorescent Protein Resistance to Photobleaching 2014
• Single Molecule Studies of PKC alpha Activation Mechanism on Membrane Surfaces 2014
• Single Molecule Studies of a Membrane-Bound, Master Kinase Circuit ... Detecting Interactions of Two Master Kinase Pairs on the Membrane, PDK1-AKT1 and PDK1-PKC Alpha 2014
• Structure and Function of the Beta-Barrel Assembly Machine and its Associated Chaperones 2014
• Sugar Alcohol Osmolytes Demonstrate the Viscosity Dependent Folding Kinetics of RNA Tertiary Structural Motifs 2014
• The Role of the C-Terminal Tails of Tubulin in Microtubule Dynamics 2014
• Torsionally Constrained DNA for Single-Molecule Assays: An Efficient, Ligation-Free Method 2014
• Understanding the Mechanisms of Human RNA Polymerase II Transcription using Single Molecule Fluorescence Colocalization 2014
• Molecular Dynamics Simulations Support the use of Methyl Generalized Order Parameters in the "Entropy Meter" 2013
• Physical Effects Controlling Flock Formation in Systems of Self-Propelled Rods 2013
• The Behavior of the Intrinsically Disordered FG Nups Determined by in Cell NMR 2013
• The Role of Kinesin-8 Proteins in Kinetochore Movements and Spindle Dynamics in Fission Yeast 2013
• Optimizing Bead Size Improves Force Precision in Optical Traps 2012
• Correlation between Properties of pHLIP Peptide-Lipid Interaction and Tumor Targeting In Vivo 2011
• High-Throughput Cell Elastic Modulus Cytometry using Single Diode Laser Bar Optical Stretchers 2011
• A Microfluidic Platform For High-Throughput Screening And Sorting Of Cells Based Upon FRET Response 2009
• Applications of Genetically Targeted and Optimized Calcium Sensors 2009
• High-speed, Thermo-chemical Nanolithography for Biological Applications 2009
• Human TBP Bending of DNA Measured at the Single Molecule Level 2009
• Molecular Mechanism of an Oncogenic Mutation that Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of AKT1 PH Domain 2009
• Single Molecule Fluorescence Studies of Membrane Targeting Proteins: Lateral Diffusion in Supported Bilayers Reveals Additional Lipid Binding Sites 2009
• Single-Molecule FRET Studies of Lysine Riboswitch Folding 2009
• Control of TGF-beta/Smad signaling 2007
• Elasticity of short DNA molecules: Quantitative agreement between theory and experiment 2007
• Multiphoton imaging for three-dimensional characterization of mixing dynamics in a microfluidic device 2007
• Measuring 0.1-nm motion in 1 MS in an optical microscope with differential-back-focal-plane detection 2005
• Photon echo spectroscopy as a probe of conformational dynamics in folded and unfolded heme proteins 2005
• Forward and reverse translocation of single RecBCD molecules on DNA 2003
• An apparent motor function for nuclear myosin I and beta-actin in transcription. 2002
• Single molecule and bulk studies of sequence-dependent pausing of lambda exonuclease 2002
• Site-specific binding of metal ions by a GNRA tetraloop 2002
• Using large-scale distributed computing to calculate accurate kinetic and thermodynamic data for macromolecular systems 2002
• Determining relative and absolute axial displacement in optical traps 2001
• Probing of metal binding domains of RNA hairpin loops by luminescence and paramagnetic NMR. 2001
• Sequence-dependent pauses observed for single lambda exonuclease molecules 2001
• Watching enzymes move along DNA one at a time 2001
• Probing RNA-metal binding domains by laser induced lanthanide luminescence. 2000
• EFFECTS OF ISOPROTERENOL ON INTRACELLULAR FREE [CA2+] DURING RELAXATION IN RAT CARDIAC MYOCYTES 1994
• EVIDENCE FOR A NEW PHOTOLYSIS INTERMEDIATE IN VISUAL PIGMENTS 1990
• TIME-RESOLVED CIRCULAR-DICHROISM STUDIES OF PROTEINS 1990
• 2-PHOTON SPECTROSCOPY OF BACTERIORHODOPSIN 1988
• THE NATURE OF THE PRIMARY PHOTOCHEMICAL EVENTS IN RHODOPSIN AND BACTERIORHODOPSIN 1988
• THE TEMPERATURE-DEPENDENCE OF P-LIGHT CHAIN PHOSPHORYLATION AND TWITCH POTENTIATION IN MOUSE EDL MUSCLE 1987
• NANOSECOND TIME RESOLVED CIRCULAR-DICHROISM SPECTROSCOPY 1986

Research

keywords

• 02 Physical Sciences, 03 Chemical Sciences, 06 Biological Sciences