Our research group in University of Colorado Boulder centers on cutting-edge micro/nano systems for various applications in biomedicine, particularly in cell manipulation, cell membrane disruption and repair, intracellular delivery and subcellular delivery. Our platform will benefit various fields in fundamental cell studies, biochemistry, medical diagnosis, and therapeutics. We aim to develop cutting-edge tools and technologies 1) for intracellular delivery of hard-to-transfer cells such as immune cells, and subcellular drug delivery, such as organelles; 2) investigate cell membrane disruption and recovery under varies of stimulation; 3) explore cell mechanics and mechanical biomarkers; 4) for protein analysis; and 5) for human healthcare, point-of-care disease diagnostics, and medical therapeutics.
keywords
microfluidics, BioMEMS, intracellular delivery, cell membrane disruption and repair, cell mechanics, drug delivery for immunotherapy and gene editing, electroporation, sonoporation, micro/nano system for intracellular delivery and subcellular delivery, micro/nano system for cell manipulation, cell sorting, cell separation, cell trapping
