Muscle soreness and serum creatine kinase activity following isometric, eccentric, and concentric exercise. Journal Article uri icon



  • Serum creatine kinase (CK) activity and subjective ratings of muscle soreness were assessed in 28 college women following three different arm flexion exercise regimens. The subjects were randomly assigned to an eccentric, isometric, or concentric exercise regimen. Each regimen was equated for total work time and work-to-rest ratio. Blood samples for determination of serum CK activity and perceived soreness ratings were obtained prior to and 5, 10, and 25 h following each exercise. Significant increases in perceived soreness ratings were observed for each exercise regimen. The magnitude of the post-exercise increase in perceived soreness was greatest for the eccentric and the isometric exercises with minimal soreness following the concentric exercise. A small but significant increase in serum CK activity was observed following the three exercises (eccentric = 35.8%, concentric = 37.6%, isometric = 34.0%). The post-exercise serum CK increases did not differ significantly among the three regimens. The rise in serum CK activity suggests that muscle damage occurred during all three tasks. However, due to multiple factors which can affect serum CK levels, the increase in serum CK activity may not provide a sensitive indicator of the magnitude of the injury.

publication date

  • June 1, 1986

has restriction

  • closed

Date in CU Experts

  • October 28, 2013 1:02 AM

Full Author List

  • Clarkson PM; Byrnes WC; McCormick KM; Turcotte LP; White JS

author count

  • 5

Other Profiles

International Standard Serial Number (ISSN)

  • 0172-4622

Additional Document Info

start page

  • 152

end page

  • 155


  • 7


  • 3