A two-step screen identifies a small molecule that disrupts membrane voltage and is effective against growing and persister gram-negative bacteria
Journal Article
Overview
publication date
- February 3, 2026
has subject area
- Animals
- Anti-Bacterial Agents
- Cell Membrane
- Cells - Macrophages
- Chemical Phenomena - Proton-Motive Force
- Connective Tissue Cells - Macrophages
- Diagnostic Techniques and Procedures - Microbial Sensitivity Tests
- Energy Metabolism - Proton-Motive Force
- Gammaproteobacteria - Salmonella typhimurium
- Gram-Negative Bacteria
- Gram-Negative Facultatively Anaerobic Rods - Salmonella typhimurium
- Humans
- Immune System - Macrophages
- Investigative Techniques - Microbial Sensitivity Tests
- Investigative Techniques - Microbial Sensitivity Tests
- Mice
- Mononuclear Phagocyte System - Macrophages
- Myeloid Cells - Macrophages
- Small Molecule Libraries
Date in CU Experts
- January 7, 2026 9:01 AM
Full Author List
- Asamoto CK; Ewing CA; Meyer CT; Allgood SC; Eldridge MJG; Evans D; Nagy TA; Christensen GL; Crooks AL; Jiang D
author count
- 12
citation count
- 0
published in
- Microbiology Spectrum Journal
Other Profiles
Electronic International Standard Serial Number (EISSN)
- 2165-0497
Digital Object Identifier (DOI)
Additional Document Info
volume
- 14
issue
- 2