Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines
Journal Article
Overview
publication date
- July 1, 1999
has subject area
- Aminoglycosides - Daunorubicin
- Aminoglycosides - Doxorubicin
- Aminoglycosides - Epirubicin
- Antineoplastic Agents
- Biochemical Phenomena - Alkylation
- Cellular Structures - Cell Nucleus
- DNA, Neoplasm
- Fluorometry - Spectrometry, Fluorescence
- Formaldehyde
- Humans
- Hydrocarbons, Aromatic - Daunorubicin
- Hydrocarbons, Aromatic - Doxorubicin
- Hydrocarbons, Aromatic - Epirubicin
- Metabolism - Alkylation
- Organelles - Cell Nucleus
- Organic Chemistry Phenomena - Alkylation
- Polycyclic Compounds - Daunorubicin
- Polycyclic Compounds - Doxorubicin
- Polycyclic Compounds - Epirubicin
- RNA, Neoplasm
- Spectrum Analysis - Spectrometry, Fluorescence
- Tumor Cells, Cultured
has restriction
- closed
Date in CU Experts
- September 3, 2013 2:59 AM
Full Author List
- Taatjes DJ; Fenick DJ; Koch TH
author count
- 3
citation count
- 41
published in
- Chemical Research in Toxicology Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0893-228X
Electronic International Standard Serial Number (EISSN)
- 1520-5010
Digital Object Identifier (DOI)
Additional Document Info
start page
- 588
end page
- 596
volume
- 12
issue
- 7