Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy
Journal Article
Overview
publication date
- August 30, 2016
has subject area
- Animals
- Biochemical Phenomena - Phosphorylation
- Blood Proteins - Antibodies
- Brain Diseases - Alzheimer Disease
- Cells - Neurofibrillary Tangles
- Cells - Neurons
- Cytoskeletal Proteins - tau Proteins
- Cytoskeleton - Neurofibrillary Tangles
- Globulins - Antibodies
- Humans
- Immunoproteins - Antibodies
- Metabolism - Phosphorylation
- Mice
- Nerve Tissue Proteins - tau Proteins
- Nervous System - Neurofibrillary Tangles
- Nervous System - Neurons
- Neurocognitive Disorders - Alzheimer Disease
- Organic Chemistry Phenomena - Phosphorylation
- Tauopathies
- Tauopathies - Alzheimer Disease
has restriction
- gold
Date in CU Experts
- September 2, 2016 8:17 AM
Full Author List
- Congdon EE; Lin Y; Rajamohamedsait HB; Shamir DB; Krishnaswamy S; Rajamohamedsait WJ; Rasool S; Gonzalez V; Levenga J; Gu J
author count
- 12
citation count
- 38
published in
- Molecular Neurodegeneration Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1750-1326
Digital Object Identifier (DOI)
Additional Document Info
volume
- 11