Metabolism - RNA Splicing
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3-DIMENSIONAL MODEL OF THE ACTIVE-SITE OF THE SELF-SPLICING RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA Journal Article
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5' EXON REQUIREMENT FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA AND IDENTIFICATION OF A CRYPTIC 5' SPLICE SITE IN THE 3' EXON Journal Article
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Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle Journal Article
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A CONSERVED BASE PAIR WITHIN HELIX-P4 OF THE TETRAHYMENA RIBOZYME HELPS TO FORM THE TERTIARY STRUCTURE REQUIRED FOR SELF-SPLICING Journal Article
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A LABILE PHOSPHODIESTER BOND AT THE LIGATION JUNCTION IN A CIRCULAR INTERVENING SEQUENCE RNA Journal Article
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A MODEL FOR THE RNA-CATALYZED REPLICATION OF RNA Journal Article
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A TERTIARY INTERACTION IN THE TETRAHYMENA INTRON CONTRIBUTES TO SELECTION OF THE 5' SPLICE-SITE Journal Article
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A TETRAHYMENA INTRON NUCLEOTIDE CONNECTED TO THE GTP ARGININE SITE Journal Article
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A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts Journal Article
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A novel family of C. elegans snRNPs contains proteins associated with trans-splicing Journal Article
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A preorganized active site in the crystal structure of the Tetrahymena ribozyme Journal Article
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ALTERATION OF SUBSTRATE-SPECIFICITY FOR THE ENDORIBONUCLEOLYTIC CLEAVAGE OF RNA BY THE TETRAHYMENA RIBOZYME Journal Article
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ALTERNATIVE SECONDARY STRUCTURES IN THE 5' EXON AFFECT BOTH FORWARD AND REVERSE SELF-SPLICING OF THE TETRAHYMENA INTERVENING SEQUENCE RNA Journal Article
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ANALYSIS OF THE STRUCTURE OF TETRAHYMENA NUCLEAR RNAS IN-VIVO - TELOMERASE RNA, THE SELF-SPLICING RIBOSOMAL-RNA INTRON, AND U2 SNRNA Journal Article
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ANTIBODIES SPECIFIC FOR BRANCHED RIBONUCLEIC-ACIDS Journal Article
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AUTOCATALYTIC CYCLIZATION OF AN EXCISED INTERVENING SEQUENCE RNA IS A CLEAVAGE LIGATION REACTION Journal Article
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Aberrant RNA splicing due to genetic incompatibilities in sunflower hybrids Journal Article
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Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(IIe) of the purple bacterium Azoarcus Journal Article
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Assembly of a ribonucleoprotein catalyst by tertiary structure capture Journal Article
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BINDING OF THE CBP2 PROTEIN TO A YEAST MITOCHONDRIAL GROUP-I INTRON REQUIRES THE CATALYTIC CORE OF THE RNA Journal Article
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BIOLOGICAL CATALYSIS BY RNA Journal Article
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Building specificity with nonspecific RNA-binding proteins Journal Article
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CATALYSIS OF RNA CLEAVAGE BY THE TETRAHYMENA-THERMOPHILA RIBOZYME .1. KINETIC DESCRIPTION OF THE REACTION OF AN RNA SUBSTRATE COMPLEMENTARY TO THE ACTIVE-SITE Journal Article
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CATALYTIC RNA - STRUCTURE AND MECHANISM Journal Article
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CONSERVED SEQUENCES AND STRUCTURES OF GROUP-I INTRONS - BUILDING AN ACTIVE-SITE FOR RNA CATALYSIS - A REVIEW Journal Article
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CONTROL OF ADENOVIRUS E1B MESSENGER-RNA SYNTHESIS BY A SHIFT IN THE ACTIVITIES OF RNA SPLICE SITES Journal Article
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COUPLING OF TETRAHYMENA RIBOSOMAL-RNA SPLICING TO BETA-GALACTOSIDASE EXPRESSION IN ESCHERICHIA-COLI Journal Article
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Christine Guthrie: Splicing genetics and mentorship into the RNA world Journal Article
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Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs Journal Article
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Circular RNAs: diversity of form and function Journal Article
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Conformational switches involved in orchestrating the successive steps of group I RNA splicing Journal Article
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Connecting genetic risk to disease end points through the human blood plasma proteome Journal Article
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Crystal structure of a group I ribozyme domain: Principles of RNA packing Journal Article
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DEFINING THE INSIDE AND OUTSIDE OF A CATALYTIC RNA MOLECULE Journal Article
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DELETION OF NONCONSERVED HELICES NEAR THE 3' END OF THE RIBOSOMAL-RNA INTRON OF TETRAHYMENA-THERMOPHILA ALTERS SELF-SPLICING BUT NOT CORE CATALYTIC ACTIVITY Journal Article
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DETECTION AND CHARACTERIZATION OF A FACTOR WHICH RESCUES SPLICEOSOME ASSEMBLY FROM A HEAT-INACTIVATED HELA-CELL NUCLEAR EXTRACT Journal Article
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DETERMINANTS OF THE 3' SPLICE SITE FOR SELF-SPLICING OF THE TETRAHYMENA PRE-RRNA Journal Article
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Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal Journal Article
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EFFICIENT PROTEIN-FACILITATED SPLICING OF THE YEAST MITOCHONDRIAL BI5 INTRON Journal Article
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Editorial overview: Nucleic acid movers and shakers Journal Article
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Effects of divalent metal ions on individual steps of the Tetrahymena ribozyme reaction Journal Article
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Evolution of Biological Catalysis: Ribozyme to RNP Enzyme Journal Article
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Exocyclic amine of the conserved G center dot U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization Journal Article
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Fast-Find: A novel computational approach to analyzing combinatorial motifs Journal Article
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Functional crosstalk between exon enhancers, polypyrimidine tracts and branchpoint sequences. Journal Article
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GUANOSINE BINDING REQUIRED FOR CYCLIZATION OF THE SELF-SPLICING INTERVENING SEQUENCE RIBONUCLEIC-ACID FROM TETRAHYMENA-THERMOPHILA Journal Article
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Genomic mRNA Profiling Reveals Compensatory Mechanisms for the Requirement of the Essential Splicing Factor U2AF Journal Article
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HNRNP-L BINDS A CIS-ACTING RNA SEQUENCE ELEMENT THAT ENABLES INTRON-INDEPENDENT GENE-EXPRESSION Journal Article
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INTERMOLECULAR EXON LIGATION OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA - OLIGONUCLEOTIDES CAN FUNCTION AS 5' EXONS Journal Article
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INVITRO SPLICING OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA - INVOLVEMENT OF A GUANOSINE NUCLEOTIDE IN THE EXCISION OF THE INTERVENING SEQUENCE Journal Article
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Identification of transcription start sites of trans-spliced genes: Uncovering unusual operon arrangements Journal Article
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In vivo selection of better self-splicing introns in Escherichia coli:: The role of the P1 extension helix of the Tetrahymena intron Journal Article
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Interplay between Exonic Splicing Enhancers, mRNA Processing, and mRNA Surveillance in the Dystrophic Mdx Mouse Journal Article
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Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status Journal Article
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Joining the two domains of a group I ribozyme to form the catalytic core Journal Article
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Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis Journal Article
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MECHANISM OF RECOGNITION OF THE 5' SPLICE SITE IN SELF-SPLICING GROUP-I INTRONS Journal Article
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METAL-ION REQUIREMENTS FOR SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME Journal Article
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MINOR-GROOVE RECOGNITION OF THE CONSERVED G-CENTER-DOT-U PAIR AT THE TETRAHYMENA RIBOZYME REACTION SITE Journal Article
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Mutations in the Tetrahymena ribozyme internal guide sequence: Effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity Journal Article
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NEW REACTIONS OF THE RIBOSOMAL-RNA PRECURSOR OF TETRAHYMENA AND THE MECHANISM OF SELF-SPLICING Journal Article
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NUCLEAR PROTEINS THAT BIND THE PREMESSENGER RNA 3' SPLICE-SITE SEQUENCE R(UUAG/G) AND THE HUMAN TELOMERIC DNA-SEQUENCE D(TTAGGG)N Journal Article
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NUCLEOTIDE CHEMISTRY .18. CHEMICAL SYNTHESIS OF BRANCHED RNA Journal Article
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Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention Journal Article
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ONE BINDING-SITE DETERMINES SEQUENCE SPECIFICITY OF TETRAHYMENA PRE-RIBOSOMAL-RNA SELF-SPLICING, TRANSSPLICING, AND RNA ENZYME-ACTIVITY Journal Article
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POLYADENYLATION SITE SELECTION CANNOT OCCUR IN-VIVO AFTER EXCISION OF THE 3'-TERMINAL INTRON Journal Article
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PROTEIN FACILITATION OF GROUP-I INTRON SPLICING BY ASSEMBLY OF THE CATALYTIC CORE AND THE 5'-SPLICE-SITE DOMAIN Journal Article
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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates Journal Article
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Quality control of assembly-defective U1 snRNAs by decapping and 5′-to-3′ exonucleolytic digestion Journal Article
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REPLACEMENT OF THE CONSERVED G-CENTER-DOT-U WITH A G-C PAIR AT THE CLEAVAGE SITE OF THE TETRAHYMENA RIBOZYME DECREASES BINDING, REACTIVITY, AND FIDELITY Journal Article
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REPRESENTATION OF THE SECONDARY AND TERTIARY STRUCTURE OF GROUP-I INTRONS Journal Article
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RESOLVING THE FUNCTIONS OF OVERLAPPING VIRAL GENES BY SITE-SPECIFIC MUTAGENESIS AT A MESSENGER-RNA SPLICE SITE Journal Article
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REVERSE SELF-SPLICING OF THE TETRAHYMENA GROUP-I INTRON - IMPLICATION FOR THE DIRECTIONALITY OF SPLICING AND FOR INTRON TRANSPOSITION Journal Article
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REVERSIBILITY OF CYCLIZATION OF THE TETRAHYMENA RIBOSOMAL-RNA INTERVENING SEQUENCE - IMPLICATION FOR THE MECHANISM OF SPLICE SITE CHOICE Journal Article
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RIBOZYME INHIBITORS - DEOXYGUANOSINE AND DIDEOXYGUANOSINE ARE COMPETITIVE INHIBITORS OF SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL RIBONUCLEIC-ACID PRECURSOR Journal Article
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RIBOZYME-MEDIATED REPAIR OF DEFECTIVE MESSENGER-RNA BY TARGETED TRANSSPLICING Journal Article
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RIBOZYMES AND THEIR MEDICAL IMPLICATIONS Journal Article
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RNA AS AN ENZYME Journal Article
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RNA AS AN ENZYME Journal Article
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RNA AS AN RNA-POLYMERASE - NET ELONGATION OF AN RNA PRIMER CATALYZED BY THE TETRAHYMENA RIBOZYME Journal Article
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RNA CATALYSIS BY A GROUP-I RIBOZYME - DEVELOPING A MODEL FOR TRANSITION-STATE STABILIZATION Journal Article
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RNA CHEMISTRY - RIBOZYME SELF-REPLICATION Journal Article
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RNA SPLICING - 3 THEMES WITH VARIATIONS Journal Article
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RNA SPLICING AND INVIVO EXPRESSION OF THE INTRON-CONTAINING TD GENE OF BACTERIOPHAGE-T4 Journal Article
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RNA-protein interactions that regulate pre-mRNA splicing Journal Article
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ROLE OF CONSERVED SEQUENCE ELEMENT-9L AND ELEMENT-2 IN SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL-RNA PRECURSOR Journal Article
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SECONDARY STRUCTURE OF THE CIRCULAR FORM OF THE TETRAHYMENA RIBOSOMAL-RNA INTERVENING SEQUENCE - A TECHNIQUE FOR RNA STRUCTURE-ANALYSIS USING CHEMICAL PROBES AND REVERSE-TRANSCRIPTASE Journal Article
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SELECTION OF CIRCULARIZATION SITES IN A GROUP-1 IVS RNA REQUIRES MULTIPLE ALIGNMENTS OF AN INTERNAL TEMPLATE-LIKE SEQUENCE Journal Article
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SELF-CATALYZED CYCLIZATION OF THE INTERVENING SEQUENCE RNA OF TETRAHYMENA - INHIBITION BY INTERCALATING DYES Journal Article
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SELF-SPLICING AND ENZYMATIC CLEAVAGE OF RNA BY A GROUP-I INTERVENING SEQUENCE Journal Article
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SELF-SPLICING AND ENZYMATIC-ACTIVITY OF AN INTERVENING SEQUENCE RNA FROM TETRAHYMENA Journal Article
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SELF-SPLICING OF THE GROUP-I INTRON FROM ANABAENA PRE-TRANSFER-RNA - REQUIREMENT FOR BASE-PAIRING OF THE EXONS IN THE ANTICODON STEM Journal Article
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SELF-SPLICING RNA - IMPLICATIONS FOR EVOLUTION Journal Article
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SELF-SPLICING RNA AND AN RNA ENZYME IN TETRAHYMENA Journal Article
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SEQUENCE REQUIREMENTS FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA Journal Article
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SEQUENCE-SPECIFIC ENDORIBONUCLEASE ACTIVITY OF THE TETRAHYMENA RIBOZYME - ENHANCED CLEAVAGE OF CERTAIN OLIGONUCLEOTIDE SUBSTRATES THAT FORM MISMATCHED RIBOZYME SUBSTRATE COMPLEXES Journal Article
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SITES OF CIRCULARIZATION OF THE TETRAHYMENA RIBOSOMAL-RNA IVS ARE DETERMINED BY SEQUENCE AND INFLUENCED BY POSITION AND SECONDARY STRUCTURE Journal Article
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SPECIFIC INTERACTION BETWEEN THE SELF-SPLICING RNA OF TETRAHYMENA AND ITS GUANOSINE SUBSTRATE - IMPLICATIONS FOR BIOLOGICAL CATALYSIS BY RNA Journal Article
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STEREOCHEMISTRY OF RNA CLEAVAGE BY THE TETRAHYMENA RIBOZYME AND EVIDENCE THAT THE CHEMICAL STEP IS NOT RATE-LIMITING Journal Article
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STRUCTURAL CONVENTIONS FOR GROUP-I INTRONS Journal Article
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STRUCTURES INVOLVED IN TETRAHYMENA RIBOSOMAL-RNA SELF-SPLICING AND RNA ENZYME-ACTIVITY Journal Article
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STUDIES ON THE HAMMERHEAD RNA SELF-CLEAVING DOMAIN Journal Article
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SUBSTRATE SEQUENCE EFFECTS ON HAMMERHEAD RNA CATALYTIC EFFICIENCY Journal Article
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Self-splicing and enzymatic activity of an intervening sequence RNA from Tetrahymena Journal Article
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Self-splicing of group I introns. Journal Article
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Self-splicing of the Tetrahymena intron from mRNA in mammalian cells Journal Article
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Sequence of the polypyrimidine tract of the 3'-terminal 3' splicing signal can affect intron-dependent pre-mRNA processing in vivo Journal Article
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Sex lethal and U2 small nuclear ribonucleoprotein auxiliary factor (U2AF(65)) recognize polypyrimidine tracts using multiple modes of binding Journal Article
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Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines Journal Article
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Split Genes: Another Surprise from Giardia Journal Article
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Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNA Journal Article
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THE CHEMISTRY OF SELF-SPLICING RNA AND RNA ENZYMES Journal Article
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THE CONSERVED U.G PAIR IN THE 5' SPLICE SITE DUPLEX OF A GROUP-I INTRON IS REQUIRED IN THE 1ST BUT NOT THE 2ND STEP OF SELF-SPLICING Journal Article
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THE GENERALITY OF SELF-SPLICING RNA - RELATIONSHIP TO NUCLEAR MESSENGER-RNA SPLICING Journal Article
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THE INTERVENING SEQUENCE RNA OF TETRAHYMENA IS AN ENZYME Journal Article
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THE TETRAHYMENA RIBOZYME ACTS LIKE AN RNA RESTRICTION ENDONUCLEASE Journal Article
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THIOPHOSPHATE INTERFERENCE EXPERIMENTS LOCATE PHOSPHATES IMPORTANT FOR THE HAMMERHEAD RNA SELF-CLEAVAGE REACTION Journal Article
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Targeting RNA structures with small molecules Journal Article
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Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components Journal Article
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The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress Journal Article
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The chemical repertoire of natural ribozymes Journal Article
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The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF65) is essential in vivo but dispensable for activity in vitro Journal Article
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Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing Journal Article
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Toward predicting self-splicing and protein-facilitated splicing of group I introns Journal Article
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Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions Journal Article
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