subject area of
- C2 domain of protein kinase Cα:: Elucidation of the membrane docking surface by site-directed fluorescence and spin labeling Journal Article
- C2 domains of protein kinase C isoforms α, β, and γ:: Activation parameters and calcium stoichiometries of the membrane-bound state Journal Article
- Ca2+ influx is an essential component of the positive-feed back loop that maintains leading-edge structure and activity in macrophages Journal Article
- Effect of PIP2 binding on the membrane docking geometry of PKCα C2 domain:: An EPR site-directed spin-labeling and relaxation study Journal Article
- Interactions of Protein Kinase C-α C1A and C1B Domains with Membranes: A Combined Computational and Experimental Study Journal Article
- Mechanism of specific membrane targeting by C2 domains:: Localized pools of target lipids enhance Ca2+ affinity Journal Article
- Membrane Docking Geometry and Target Lipid Stoichiometry of Membrane-Bound PKCα C2 Domain: A Combined Molecular Dynamics and Experimental Study Journal Article
- PDK1:PKCa heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane Journal Article
- Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway Journal Article
- Single-Molecule Studies Reveal a Hidden Key Step in the Activation Mechanism of Membrane-Bound Protein Kinase C-α Journal Article
- Specific translocation of protein kinase Cα to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain Journal Article