The fundamental goal of my lab's research is to provide mechanistic insight into how architectural changes in chromatin regulate gene expression. We aim to discover the mechanisms underlying heterochromatin formation and establishment, and how such processes control cell type identity. Our work has broad implications for understanding the transcriptional/heterochromatin changes during cancer progression and metastasis.
BCHM 5781 - Advanced General Biochemistry 2
Spring 2022 / Spring 2023
Lect. Detailed consideration of contemporary topics in biochemistry, including protein structure (primary, secondary, tertiary, and quaternary), methods of structure determination and prediction, protein folding (kinetics, thermodynamics, denaturation, and renaturation), and protein dynamics (internal motions and methods of analysis). Formerly CHEM 5781.
MCDB 6000 - Introduction to Laboratory Methods
Fall 2022 / Spring 2023
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.