Gene for von Recklinghausen Neurofibromatosis Is in the Pericentromeric Region of Chromosome 17 Journal Article uri icon



  • Linkage analysis of 15 Utah kindreds demonstrated that a gene responsible for von Recklinghausen neurofibromatosis (NF) is located near the centromere on chromosome 17. The families also gave no evidence for heterogeneity, indicating that a significant proportion of NF cases are due to mutations at a single locus. Further genetic analysis can now refine this localization and may lead to the eventual identification and cloning of the defective gene responsible for this disorder.

publication date

  • May 29, 1987

has restriction

  • closed

Date in CU Experts

  • May 3, 2014 11:03 AM

Full Author List

  • Barker D; Wright E; Nguyen K; Cannon L; Fain P; Goldgar D; Bishop DT; Carey J; Baty B; Kivlin J

author count

  • 20

Other Profiles

International Standard Serial Number (ISSN)

  • 0036-8075

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

Additional Document Info

start page

  • 1100

end page

  • 1102


  • 236


  • 4805