Crystal structure of HsIUV complexed with a vinyl sulfone inhibitor: Corroboration of a proposed mechanism of allosteric activation of HsIV by HsIU
Journal Article
Overview
publication date
- May 3, 2002
has subject area
- Acid Anhydride Hydrolases - ATP-Dependent Proteases
- Adenosine Triphosphatases
- Adenosine Triphosphatases - ATP-Dependent Proteases
- Allosteric Regulation
- Binding Sites - Catalytic Domain
- Biochemical Phenomena - Enzyme Activation
- Carrier Proteins - ATP-Dependent Proteases
- Crystallography, X-Ray
- Cysteine Proteases - Cysteine Endopeptidases
- Endopeptidases
- Endopeptidases - Cysteine Endopeptidases
- Endopeptidases - Serine Endopeptidases
- Enzymes - Multienzyme Complexes
- Enzymes - Proteasome Endopeptidase Complex
- Gammaproteobacteria - Haemophilus influenzae
- Gram-Negative Facultatively Anaerobic Rods - Haemophilus influenzae
- Heat-Shock Proteins
- Macromolecular Substances
- Metabolism - Enzyme Activation
- Models, Molecular
- Multiprotein Complexes - Multienzyme Complexes
- Multiprotein Complexes - Proteasome Endopeptidase Complex
- Peptide Hydrolases - ATP-Dependent Proteases
- Peptide Hydrolases - Proteasome Endopeptidase Complex
- Protease Inhibitors
- Protein Conformation
- Protein Structural Elements - Catalytic Domain
- Recombinant Proteins
- Serine Proteases - Serine Endopeptidases
- Substrate Specificity
- Sulfones
has restriction
- closed
Date in CU Experts
- October 18, 2013 3:36 AM
Full Author List
- Sousa MC; Kessler BM; Overkleeft HS; McKay DB
author count
- 4
citation count
- 53
published in
- Journal of Molecular Biology Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0022-2836
Electronic International Standard Serial Number (EISSN)
- 1089-8638
Digital Object Identifier (DOI)
Additional Document Info
start page
- 779
end page
- 785
volume
- 318
issue
- 3