Tunable liquid lens for three-photon excitation microscopy Journal Article

• Best Open Access

Overview

abstract

• We demonstrate a novel electrowetting liquid combination using a room temperature ionic liquid (RTIL) and a nonpolar liquid, 1-phenyl-1-cyclohexene (PCH) suitable for focus-tunable 3-photon microscopy. We show that both liquids have over 90% transmission at 1300 nm over a 1.1 mm pathlength and an index of refraction contrast of 0.123. A lens using these liquids can be tuned from a contact angle of 133 to 48° with applied voltages of 0 and 60 V, respectively. Finally, a three-photon imaging system including an RTIL electrowetting lens was used to image a mouse brain slice. Axial scans taken with an electrowetting lens show excellent agreement with images acquired using a mechanically scanned objective.

CU Boulder Authors

• Gopinath, Juliet T

publication date

• May 1, 2024

has restriction

• gold

Date in CU Experts

• May 1, 2024 1:22 AM

Full Author List

• Gilinsky SD; Jung DN; Futia GL; Zohrabi M; Welton TA; Supekar OD; Gibson EA; Restrepo D; Bright VM; Gopinath JT

author count

• 10

published in

• Biomedical Optics Express  Journal

Other Profiles

International Standard Serial Number (ISSN)

• 2156-7085

Electronic International Standard Serial Number (EISSN)

• 2156-7085

Digital Object Identifier (DOI)

• https://doi.org/10.1364/boe.516956

Additional Document Info

start page

• 3285

end page

• 3285

volume

• 15

issue

• 5