Injectable and protease-degradable hydrogel for siRNA sequestration and triggered delivery to the heart
Journal Article
Overview
publication date
- September 10, 2018
has subject area
- Animals
- Cell Line - NIH 3T3 Cells
- Cells, Cultured
- Complex Mixtures - Hydrogels
- Drug Delivery Systems
- Drug Delivery Systems - Delayed-Action Preparations
- Endopeptidases - Matrix Metalloproteinase 2
- Endopeptidases - Matrix Metalloproteinase 2
- Endopeptidases - Matrix Metalloproteinase 2
- Fibroblasts - NIH 3T3 Cells
- Heart - Myocardium
- Heart Diseases - Myocardial Infarction
- Injections
- Ischemia - Myocardial Infarction
- Male
- Metalloproteases - Matrix Metalloproteinase 2
- Metalloproteases - Matrix Metalloproteinase 2
- Metalloproteases - Matrix Metalloproteinase 2
- Mice
- Muscle, Striated - Myocardium
- Musculoskeletal System - Myocardium
- Necrosis - Myocardial Infarction
- Nucleic Acids, Nucleotides, and Nucleosides - RNA, Small Interfering
- Peptide Hydrolases
- Peptides - Matrix Metalloproteinase 2
- Pharmaceutical Preparations - Delayed-Action Preparations
- Pharmaceutical Preparations - Hydrogels
- Proteins - Matrix Metalloproteinase 2
- RNA - RNA, Small Interfering
- RNA, Small Untranslated - RNA, Small Interfering
- RNAi Therapeutics
- Rats, Wistar
- Vascular Diseases - Myocardial Infarction
has restriction
- green
Date in CU Experts
- January 2, 2023 9:19 AM
Full Author List
- Wang LL; Chung JJ; Li EC; Uman S; Atluri P; Burdick JA
author count
- 6
citation count
- 75
published in
- Journal of Controlled Release Journal
Other Profiles
International Standard Serial Number (ISSN)
- 0168-3659
Electronic International Standard Serial Number (EISSN)
- 1873-4995
Digital Object Identifier (DOI)
Additional Document Info
start page
- 152
end page
- 161
volume
- 285