Misregulation of synaptic function results in abnormal brain function and behavior that is manifested in numerous neurological and psychiatric diseases. Explores the molecular mechanisms responsible for altered synaptic plasticity in neurological diseases such as frontotemporal dementia (FTD), Parkinson's disease, Huntington's disease, Creutzfeldt-Jakob disease, Down syndrome, epilepsy, autism, and Alzheimer's disease. Recommended prerequisites: MCDB 3650 or NRSC 2100 (minimum grade C-) or instructor consent required.
