subject area of
- A Closed Form Model for Molecular Ratchet-Type Chemically Induced Dimerization Modules Journal Article
- A Structural Basis for the Recognition of 2′-Deoxyguanosine by the Purine Riboswitch Journal Article
- A coat for all sequences Journal Article
- A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity Journal Article
- A switch in time: Detailing the life of a riboswitch Journal Article
- A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment Journal Article
- Accurate and efficient corrections for missing dispersion interactions in molecular Simulations Journal Article
- Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs Journal Article
- Analysis of Ligand-Dependent Nuclear Accumulation of Smads in TGF-beta Signaling Journal Article
- Authentication of a lophotrochozoan adipokinetic hormone receptor in a Gastropod, Aplysia californica Journal Article
- B12 cofactors directly stabilize an mRNA regulatory switch Journal Article
- Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase Journal Article
- Best Practices in Free Energy Calculations for Drug Design Journal Article
- Blocking transcription through a nucleosome with synthetic DNA ligands Journal Article
- CALCIUM(II) SITE SPECIFICITY - EFFECT OF SIZE AND CHARGE ON METAL-ION BINDING TO AN EF-HAND-LIKE SITE Journal Article
- CBASS Immunity Uses CARF-Related Effectors to Sense 3′-5′- and 2′-5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection Journal Article
- Calorimetric Measurement of SH2 Domain Ligand Affinities Journal Article
- Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments Journal Article
- Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange Journal Article
- Click Conjugation of Cloaked Peptide Ligands to Microbubbles Journal Article
- Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin Journal Article
- Connecting Protein Conformation and Dynamics with Ligand-Receptor Binding Using Three-Color Forster Resonance Energy Transfer Tracking Journal Article
- Conserved structure for single-stranded telomeric DNA recognition Journal Article
- Controlling electron transfer through the manipulation of structure and ligand-based torsional motions: a computational exploration of ruthenium donor-acceptor systems using density functional theory. Journal Article
- Copper(II) Binding by Dissolved Organic Matter: Importance of the Copper-to-Dissolved Organic Matter Ratio and Implications for the Biotic Ligand Model Journal Article
- Crystal structure of the lysine riboswitch regulatory mRNA element Journal Article
- Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands Journal Article
- DIVERSITY OF OLIGONUCLEOTIDE FUNCTIONS Journal Article
- Decoding the quantitative nature of TGF-β/Smad signaling Journal Article
- Design and engineering of genetically encoded protein biosensors for small molecules Journal Article
- Development and Benchmarking of Open Force Field 2.0.0: The Sage Small Molecule Force Field Journal Article
- Development and Benchmarking of Open Force Field v1.0.0-the Parsley Small-Molecule Force Field Journal Article
- Dimensionality is the issue: use of photoaptamers in protein microarrays Journal Article
- Direct calculation of the binding free energies of FKBP ligands Journal Article
- Discrimination against RNA Backbones by a ssDNA Binding Protein Journal Article
- Dynamic and Thermodynamic Response of the Ras Protein Cdc42Hs upon Association with the Effector Domain of PAK3 Journal Article
- EVIDENCE THAT TRICYCLIC SMALL MOLECULES MAY POSSESS TOLL-LIKE RECEPTOR AND MYELOID DIFFERENTIATION PROTEIN 2 ACTIVITY Journal Article
- Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics Journal Article
- Entropy in molecular recognition by proteins Journal Article
- Evidence that both ligand binding and covalent adaptation drive a two-state equilibrium in the aspartate receptor signaling complex Journal Article
- Evolution of the endothelin pathway drove neural crest cell diversification Journal Article
- Expanded Ensemble Methods Can be Used to Accurately Predict Protein-Ligand Relative Binding Free Energies Journal Article
- Exploiting conformational dynamics to facilitate formation and trapping of electron-transfer photoproducts in metal complexes. Journal Article
- Fgf signaling is required for zebrafish tooth development Journal Article
- Fit for the Eye: Aptamers in Ocular Disorders Journal Article
- Fractionation of Fulvic Acid by Iron and Aluminum Oxides-Influence on Copper Toxicity to Ceriodaphnia dubia Journal Article
- From oligonucleotide shapes to genomic SELEX: Novel biological regulatory loops Journal Article
- HIGH-AFFINITY RNA LIGANDS TO ESCHERICHIA-COLI RIBOSOMES AND RIBOSOMAL-PROTEIN S1 - COMPARISON OF NATURAL AND UNNATURAL BINDING-SITES Journal Article
- Hedgehog signaling is required at multiple stages of zebrafish tooth development Journal Article
- High Affinity Binding of N2-Modified Guanine Derivatives Significantly Disrupts the Ligand Binding Pocket of the Guanine Riboswitch Journal Article
- High Energy Density Nanocomposites Based on Surface-Modified BaTiO3 and a Ferroelectric Polymer Journal Article
- High affinity ligands from in vitro selection:: Complex targets Journal Article
- Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells Journal Article
- Human CRSP interacts with RNA polymerase IICTD and adopts a specific CTD-bound conformation Journal Article
- IN-VITRO SELECTION OF RNA LIGANDS TO SUBSTANCE-P Journal Article
- ISOLATION OF HIGH-AFFINITY RNA LIGANDS TO HIV-1 INTEGRASE FROM A RANDOM POOL Journal Article
- Impact of flow on ligand-mediated bacterial flocculation Journal Article
- Improved Force Spectroscopy Using Focused-Ion-Beam-Modified Cantilevers Journal Article
- Improved Free-Energy Landscape Quantification Illustrated with a Computationally Designed Protein-Ligand Interaction Journal Article
- In vitro evolution of the DNA binding sites of Escherichia coli methionine repressor, MetJ Journal Article
- In vitro selection of a novel catalytic RNA: Characterization of a sulfur alkylation reaction and interaction with a small peptide Journal Article
- Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A2 Journal Article
- Infrared spectroscopy of hydrated naphthalene cluster anions Journal Article
- Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus Journal Article
- Lessons learned from comparing molecular dynamics engines on the SAMPL5 dataset Journal Article
- Ligand identification in CryoEM and X-ray maps using deep learning Journal Article
- Ligand-Enhanced Abiotic Iron Oxidation and the Effects of Chemical versus Biological Iron Cycling in Anoxic Environments Journal Article
- Ligand-Free Copper(I)-Mediated Cross-Coupling Reactions of Organostannanes with Sulfur Electrophiles Journal Article
- Ligand-dependent folding of the three-way junction in the purine riboswitch Journal Article
- Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-β signaling Journal Article
- Ligand-mediated protection against phage lysis as a positive selection strategy for the enrichment of epitopes displayed on the surface of E-coli cells Journal Article
- MODELS FOR COPPER-CONTAINING PROTEINS - STRUCTURE AND PROPERTIES OF NOVEL 5-COORDINATE COPPER(I) COMPLEXES Journal Article
- Measuring TGF-β Ligand Dynamics in Culture Medium Journal Article
- Mix-and-match riboswitches Journal Article
- Modifying network chemistry in thiol-acrylate photopolymers through postpolymerization functionalization to control cell-material interactions Journal Article
- Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection Journal Article
- Monitoring RNA-ligand interactions using isothermal titration calorimetry. Journal Article
- Monodispersity Increases Adhesion Efficiency and Specificity for Ultrasound-Targeted Microbubbles Journal Article
- Mutational analysis of the purine riboswitch aptamer domain Journal Article
- NMR Chemical Exchange as a Probe for Ligand-Binding Kinetics in a Theophylline-Binding RNA Aptamer Journal Article
- Nanocomposite "Superhighways" by Solution Assembly of Semiconductor Nanostructures with Ligand-Functionalized Conjugated Polymers Journal Article
- Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking Journal Article
- Novel methods of generating specific oligonucleotide inhibitors of viral polymerases Journal Article
- Nucleotides Adjacent to the Ligand-Binding Pocket are Linked to Activity Tuning in the Purine Riboswitch Journal Article
- On-Chip Acousto Thermal Shift Assay for Rapid and Sensitive Assessment of Protein Thermodynamic Stability Journal Article
- Overview of the SAMPL5 host-guest challenge: Are we doing better? Journal Article
- Parallelized-over-parts computation of absolute binding free energy with docking and molecular dynamics Journal Article
- Patterning of Self-Assembled Monolayers of Amphiphilic Multisegment Ligands on Nanoparticles and Design Parameters for Protein Interactions Journal Article
- Photo-Click Living Strategy for Controlled, Reversible Exchange of Biochemical Ligands Journal Article
- Post-SELEX combinatorial optimization of aptamers Journal Article
- Quantifying a light- induced energetic change in bacteriorhodopsin by force spectroscopy Journal Article
- Quantitation of free energy profiles in RNA-ligand interactions by nucleotide analog interference mapping Journal Article
- Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: Development of a heterogeneous two-state model Journal Article
- RNA LIGANDS TO HUMAN NERVE GROWTH-FACTOR Journal Article
- RNA PSEUDOKNOTS THAT INHIBIT HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE Journal Article
- RNA aptamers as pathway-specific MAP kinase inhibitors Journal Article
- RNA replication by Q beta replicase: A working model Journal Article
- RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme Journal Article
- RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers Journal Article
- Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds Journal Article
- Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate Journal Article
- Rationalizing Diverse Binding Mechanisms to the Same Protein Fold: Insights for Ligand Recognition and Biosensor Design Journal Article
- Reflections on mirrors Journal Article
- Regulation of Gene Expression Through Effector-dependent Conformational Switching by Cobalamin Riboswitches Journal Article
- Replication Protein A Utilizes Differential Engagement of Its DNA- Binding Domains to Bind Biologically Relevant ssDNAs in Diverse Binding Modes Journal Article
- Requirements for efficient ligand-gated co-transcriptional switching in designed variants of the B. subtilis pbuE adenine-responsive riboswitch in E. coli Journal Article
- Riboswitches: Fold and function Journal Article
- Role of a heterogeneous free state in the formation of a specific RNA-theophylline complex Journal Article
- Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA Journal Article
- SELECTION OF HIGH-AFFINITY RNA LIGANDS TO REVERSE-TRANSCRIPTASE - INHIBITION OF CDNA SYNTHESIS AND RNASE-H ACTIVITY Journal Article
- SELECTION OF HIGH-AFFINITY RNA LIGANDS TO THE BACTERIOPHAGE-R17 COAT PROTEIN Journal Article
- SELECTIVE ENRICHMENT OF RNA SPECIES FOR TIGHT-BINDING TO ESCHERICHIA-COLI RHO-FACTOR Journal Article
- SELEXION - SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT WITH INTEGRATED OPTIMIZATION BY NONLINEAR-ANALYSIS Journal Article
- SITEHOUND-web: a server for ligand binding site identification in protein structures Journal Article
- SPRINT: a Cas13a-based platform for detection of small molecules Journal Article
- SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT - RNA LIGANDS TO BACTERIOPHAGE-T4 DNA-POLYMERASE Journal Article
- Self-assembly of linear arrays of semiconductor nanoparticles on carbon single-walled nanotubes Journal Article
- Single-Molecule Conformational Dynamics of a Biologically Functional Hydroxocobalamin Riboswitch Journal Article
- Single-Molecule Studies of the Lysine Riboswitch Reveal Effector-Dependent Conformational Dynamics of the Aptamer Domain Journal Article
- Site-directed mutagenesis reveals the thermodynamic requirements for single-stranded DNA recognition by the telomere-binding protein Cdc13 Journal Article
- SnoN and Ski protooncoproteins ave rapidly degraded in response to transforming growth factor β signaling Journal Article
- Solvent-Driven Reductive Activation of Carbon Dioxide by Gold Anions Journal Article
- Sticky surface: sphere-sphere adhesion dynamics Journal Article
- Structural basis for 2′-deoxyguanosine recognition by the 2′-dG-II class of riboswitches Journal Article
- Structural studies of the purine and SAM binding riboswitches Journal Article
- Structure and mechanism of ArnA: Conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance Journal Article
- Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine Journal Article
- Structure of the S-adenosylmethionine riboswitch regulatory mRNA element Journal Article
- Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch Journal Article
- Structure-Assisted Functional Anchor Implantation in Robust Metal-Organic Frameworks with Ultra large Pores Journal Article
- Studies of targeting and intracellular trafficking of an anti-androgen doxorubicin-formaldehyde conjugate in PC-3 prostate cancer cells bearing androgen receptor-GFP chimera Journal Article
- Targeting Riboswitches with Beta-Axial-Substituted Cobalamins Journal Article
- Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance Journal Article
- Tetranuclear iron(III) complexes of an octadentate pyridine-carboxylate ligand and their catalytic activity in alkane oxidation by hydrogen peroxide Journal Article
- The SAMPL6 SAMPLing challenge: assessing the reliability and efficiency of binding free energy calculations Journal Article
- The SELEX process: a surprising source of therapeutic and diagnostic compounds. Journal Article
- The Structure of a Tetrahydrofolate-Sensing Riboswitch Reveals Two Ligand Binding Sites in a Single Aptamer Journal Article
- The effects of hydroxyapatite nanoparticles embedded in a MMP-sensitive photoclickable PEG hydrogel on encapsulated MC3T3-E1 pre-osteoblasts Journal Article
- The mathematics of SELEX against complex targets Journal Article
- The use of aptamers in large arrays for molecular diagnostics. Journal Article
- The β3 nicotinic receptor subunit:: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors Journal Article
- Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain Journal Article
- Thermosensitive P(AAc-co-NIPAm) Hydrogels Display Enhanced Toughness and Self-Healing via Ion-Ligand Interactions Journal Article
- Time-resolved photoconductivity of PbSe nanocrystal arrays Journal Article
- Toehold-Mediated Displacement of an Adenosine-Binding Aptamer from a DNA Duplex by its Ligand Journal Article
- Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant Journal Article
- Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta 2 subunit Journal Article
- Two-step Ligand Binding in a (βα)8 Barrel Enzyme SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA Journal Article
- Use of a partial-filling technique in affinity capillary electrophoresis for determining binding constants of ligands to receptors. Journal Article
- Using in vitro selection to direct the covalent attachment of human immunodeficiency virus type 1 Rev protein to high-affinity RNA ligands Journal Article
- Vascular Grafts with Tailored Stiffness and a Ligand Environment via Multiarmed Polymer Sheath for Expeditious Regeneration Journal Article
- Versatile derivatives of carbohydrate-binding modules for imaging of complex carbohydrates approaching the molecular level of resolution Journal Article
- Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase Journal Article
- Zebraf ish fgf24 functions with fgf8 to promote posterior mesodermal development Journal Article
- p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice Journal Article